Search Results - "Zhu, Wensi"

Predicting the structure of large protein complexes using AlphaFold and Monte Carlo tree search by Bryant, Patrick, Pozzati, Gabriele, Zhu, Wensi, Shenoy, Aditi, Kundrotas, Petras, Elofsson, Arne

“…AlphaFold can predict the structure of single- and multiple-chain proteins with very high accuracy. However, the accuracy decreases with the number of chains,…”
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Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9 by Zhu, Wensi, Han, Linxiao, Wu, Yuanyuan, Tong, Lin, He, Ludan, Wang, Qin, Yan, Yu, Pan, Ting, Shen, Jie, Song, Yuanlin, Shen, Yao, Zhu, Qiaoliang, Zhou, Jian

“…Chronic obstructive pulmonary disease (COPD), a chronic inflammatory lung disease, is a leading cause of morbidity and mortality worldwide. Prolonged cigarette…”
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Involvement of Smad3 pathway in atrial fibrosis induced by elevated hydrostatic pressure by Wei, Wei, Rao, Fang, Liu, Fangzhou, Xue, Yumei, Deng, Chunyu, Wang, Zhaoyu, Zhu, Jiening, Yang, Hui, Li, Xin, Zhang, Mengzhen, Fu, Yongheng, Zhu, Wensi, Shan, Zhixin, Wu, Shulin

“…Hypertension is a main risk factor for atrial fibrillation, but the direct effects of hydrostatic pressure on the atrial fibrosis are still unknown. The…”
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Lyophilized powder of mesenchymal stem cell supernatant attenuates acute lung injury through the IL-6-p-STAT3-p63-JAG2 pathway by Peng, Wenjun, Chang, Meijia, Wu, Yuanyuan, Zhu, Wensi, Tong, Lin, Zhang, Ge, Wang, Qin, Liu, Jie, Zhu, Xiaoping, Cheng, Tingting, Li, Yijia, Chen, Xi, Weng, Dong, Liu, Sanhong, Zhang, Hongwei, Su, Yao, Zhou, Jian, Li, Huayin, Song, Yuanlin

“…Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are syndromes of acute respiratory failure with extremely high mortality and few…”
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Lianhua Qingke ameliorates lipopolysaccharide‐induced lung injury by inhibiting neutrophil extracellular traps formation and pyroptosis by Peng, Wenjun, Qi, Hui, Zhu, Wensi, Tong, Lin, Rouzi, Ainiwaer, Wu, Yuanyuan, Han, Linxiao, He, Ludan, Yan, Yu, Pan, Ting, Liu, Jie, Wang, Qin, Jia, Zhenhua, Song, Yuanlin, Zhu, Qiaoliang, Zhou, Jian

“…LHQK is a patented Traditional Chinese Medicine (TCM) which is clinically used for acute tracheobronchitis, cough, and other respiratory diseases. Recent…”
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The traditional Chinese patented medicine Qingke Pingchuan granules alleviate acute lung injury by regenerating club cells by Wu, Yuanyuan, Zhu, Wensi, Rouzi, Ainiwaer, Tong, Lin, Han, Linxiao, Song, Juan, Ding, Jianwen, Yan, Yu, Li, Miao, Pan, Ting, Liu, Jie, Wang, Qin, Song, Yuanlin, Shen, Jie, Zhou, Jian

“…Qingke Pingchuan granules (QKPCG), a patented traditional Chinese medicine, clinically, are recommended for acute tracheobronchitis, cough, community‐acquired…”
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Evaluation of AlphaFold-Multimer prediction on multi-chain protein complexes by Zhu, Wensi, Shenoy, Aditi, Kundrotas, Petras, Elofsson, Arne

“…Abstract Motivation Despite near-experimental accuracy on single-chain predictions, there is still scope for improvement among multimeric predictions. Methods…”
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Limits and potential of combined folding and docking by Pozzati, Gabriele, Zhu, Wensi, Bassot, Claudio, Lamb, John, Kundrotas, Petras, Elofsson, Arne

“…Abstract Motivation In the last decade, de novo protein structure prediction accuracy for individual proteins has improved significantly by utilising deep…”
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Towards a structurally resolved human protein interaction network by Burke, David F., Bryant, Patrick, Barrio-Hernandez, Inigo, Memon, Danish, Pozzati, Gabriele, Shenoy, Aditi, Zhu, Wensi, Dunham, Alistair S., Albanese, Pascal, Keller, Andrew, Scheltema, Richard A., Bruce, James E., Leitner, Alexander, Kundrotas, Petras, Beltrao, Pedro, Elofsson, Arne

“…Cellular functions are governed by molecular machines that assemble through protein-protein interactions. Their atomic details are critical to studying their…”
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A structural biology community assessment of AlphaFold2 applications by Akdel, Mehmet, Pires, Douglas E. V., Pardo, Eduard Porta, Jänes, Jürgen, Zalevsky, Arthur O., Mészáros, Bálint, Bryant, Patrick, Good, Lydia L., Laskowski, Roman A., Pozzati, Gabriele, Shenoy, Aditi, Zhu, Wensi, Kundrotas, Petras, Serra, Victoria Ruiz, Rodrigues, Carlos H. M., Dunham, Alistair S., Burke, David, Borkakoti, Neera, Velankar, Sameer, Frost, Adam, Basquin, Jérôme, Lindorff-Larsen, Kresten, Bateman, Alex, Kajava, Andrey V., Valencia, Alfonso, Ovchinnikov, Sergey, Durairaj, Janani, Ascher, David B., Thornton, Janet M., Davey, Norman E., Stein, Amelie, Elofsson, Arne, Croll, Tristan I., Beltrao, Pedro

“…Most proteins fold into 3D structures that determine how they function and orchestrate the biological processes of the cell. Recent developments in…”
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The cuproptosis-related gene glutaminase promotes alveolar macrophage copper ion accumulation in chronic obstructive pulmonary disease by Han, Linxiao, Zhu, Wensi, Qi, Hui, He, Ludan, Wang, Qin, Shen, Jie, Song, Yuanlin, Shen, Yao, Zhu, Qiaoliang, Zhou, Jian

“…•The contribution of cuproptosis to the onset or progression of chronic obstructive pulmonary disease.•Cuproptosis-related gene glutaminase (GLS) was firstly…”
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CDK6 mediates the effect of attenuation of miR-1 on provoking cardiomyocyte hypertrophy by Yuan, Weiwei, Tang, Chunmei, Zhu, Wensi, Zhu, Jiening, Lin, Qiuxiong, Fu, Yongheng, Deng, Chunyu, Xue, Yumei, Yang, Min, Wu, Shulin, Shan, Zhixin

“…MicroRNA-1 (miR-1) is approved involved in cardiac hypertrophy, but the underlying molecular mechanisms of miR-1 in cardiac hypertrophy are not well…”
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GLIPRI Protects Against Cigarette Smoke-Induced Airway Inflammation via PLAU/EGFR Signaling by Peng, Wenjun, Wu, Yuanyuan, Zhang, Ge, Zhu, Wensi, Chang, Meijia, Rouzi, Ainiwaer, Jiang, Weipeng, Tong, Lin, Wang, Qin, Liu, Jie, Song, Yuanlin, Li, Huayin, Li, Ka, Zhou, Jian

“…Background: Chronic obstructive pulmonary disease (COPD) is a major health problem associated with high mortality worldwide. Cigarette smoke (CS) exposure is…”
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N-terminal truncation mutations of adenomatous polyposis coli are associated with primary cilia defects by Song, Li, Jia, Yuxin, Zhu, Wensi, Newton, Ian P., Li, Zhuoyu, Li, Wenling

“…•Expression of N-terminal APC fragments cause primary cilia defects.•A loop of β-catenin/PI3K/AKT/GSK-3β mediates APC mutations-induced cilia loss.•Elevated…”
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A novel Ku-band microstrip triple-mode filter using stub-loaded resonator by Zhu Wensi, Zhang Junru, Yu Mengxia

“…This paper presents a novel Ku-band microstrip triple-mode bandpass filters with good square ratio and wide stopband rejection. The proposed novel triple-mode…”
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Macrophage migration inhibitory factor promotes expression of GLUT4 glucose transporter through MEF2 and Zac1 in cardiomyocytes by Liang, Yeyou, Yuan, Weiwei, Zhu, Wensi, Zhu, Jiening, Lin, Qiuxiong, Zou, Xiao, Deng, Chunyu, Fu, Yongheng, Zheng, Xilong, Yang, Min, Wu, Shulin, Yu, Xiyong, Shan, Zhixin

“…Abstract Objective Evidence shows that both macrophage migration inhibitory factor (MIF) and GLUT4 glucose transporter are involved in diabetic cardiomyopathy…”
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GLIPR1 Protects Against Cigarette Smoke-Induced Airway Inflammation via PLAU/EGFR Signaling by Peng, Wenjun, Wu, Yuanyuan, Zhang, Ge, Zhu, Wensi, Chang, Meijia, Rouzi, Ainiwaer, Jiang, Weipeng, Tong, Lin, Wang, Qin, Liu, Jie, Song, Yuanlin, Li, Huayin, Li, Ka, Zhou, Jian

“…Chronic obstructive pulmonary disease (COPD) is a major health problem associated with high mortality worldwide. Cigarette smoke (CS) exposure is the main…”
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Design of ultra wide band transition connector for GTEM cell by Zhang Junru, Zhu Wensi, Yu Mengxia, Wang Yuanyuan

“…The transition connector plays a vital role in the study of Gigahertz Transverse Electro Magnetic cell (GTEM Cell). An ultra wide band transition connector is…”
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MicroRNA-199a-3p enhances expressions of fibrosis-associated genes through targeting Smad1 in mouse cardiac fibroblasts by Liang, Jingnan, Zhu, Wensi, Zhang, Zhuo, Zhu, Jiening, Fu, Yongheng, Lin, Qiuxiong, Kuang, Sujuan, Zhang, Mengzhen, Shan, Zhixin

“…To investigate the role of miR-199a-3p in cardiac fibrosis and the potential target of miR-199a-3p. Cardiac fibroblasts were isolated from C57BL/6 mice and…”
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IEEE 1588 implementation with FLL vs. PLL by Zhu, Wensi

“…This paper discusses the IEEE 1588 implementation with Frequency Locked Loop (FLL) and Phase Locked Loop (PLL). The work was supported by a Telecom technology…”
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