Search Results - "Zhu, Shuangli"

Combination strategies with PD-1/PD-L1 blockade: current advances and future directions by Yi, Ming, Zheng, Xiaoli, Niu, Mengke, Zhu, Shuangli, Ge, Hong, Wu, Kongming

“…Antibodies targeting programmed cell death protein-1 (PD-1) or its ligand PD-L1 rescue T cells from exhausted status and revive immune response against cancer…”
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Developing a hybrid model of Jaya algorithm-based extreme gradient boosting machine to estimate blast-induced ground vibrations by Zhou, Jian, Qiu, Yingui, Khandelwal, Manoj, Zhu, Shuangli, Zhang, Xiliang

“…Blasting is still being considered to be one the most important applicable alternatives for conventional excavations. Ground vibration generated due to…”
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Estimation of the TBM advance rate under hard rock conditions using XGBoost and Bayesian optimization by Zhou, Jian, Qiu, Yingui, Zhu, Shuangli, Armaghani, Danial Jahed, Khandelwal, Manoj, Mohamad, Edy Tonnizam

“…The advance rate (AR) of a tunnel boring machine (TBM) under hard rock conditions is a key parameter in the successful implementation of tunneling engineering…”
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Recent advances in targeted strategies for triple-negative breast cancer by Zhu, Shuangli, Wu, Yuze, Song, Bin, Yi, Ming, Yan, Yuheng, Mei, Qi, Wu, Kongming

“…Triple-negative breast cancer (TNBC), a highly aggressive subtype of breast cancer, negatively expresses estrogen receptor, progesterone receptor, and the…”
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Predicting tunnel squeezing using support vector machine optimized by whale optimization algorithm by Zhou, Jian, Zhu, Shuangli, Qiu, Yingui, Armaghani, Danial Jahed, Zhou, Annan, Yong, Weixun

“…The squeezing behavior of surrounding rock can be described as the time-dependent large deformation during tunnel excavation, which appears in special…”
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Combine and conquer: manganese synergizing anti-TGF-β/PD-L1 bispecific antibody YM101 to overcome immunotherapy resistance in non-inflamed cancers by Yi, Ming, Niu, Mengke, Zhang, Jing, Li, Shiyu, Zhu, Shuangli, Yan, Yongxiang, Li, Ning, Zhou, Pengfei, Chu, Qian, Wu, Kongming

“…Our previous work showed that the anti-TGF-β/PD-L1 bispecific antibody YM101 effectively overcame anti-PD-L1 resistance in immune-excluded tumor models…”
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Microenvironment responsive nanocomposite hydrogel with NIR photothermal therapy, vascularization and anti-inflammation for diabetic infected wound healing by Zhu, Shuangli, Zhao, Bangjiao, Li, Maocai, Wang, Hao, Zhu, Jiayi, Li, Qingtao, Gao, Huichang, Feng, Qi, Cao, Xiaodong

“…Bacterial infection, excessive inflammation and damaging blood vessels network are the major factors to delay the healing of diabetic ulcer. At present, most…”
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Recent advances and challenges of bispecific antibodies in solid tumors by Wu, Yuze, Yi, Ming, Zhu, Shuangli, Wang, Haiyong, Wu, Kongming

“…Cancer immunotherapy has made remarkable progress in the past decade. Bispecific antibodies (BsAbs) have acquired much attention as the next generation…”
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Isolation of 2019-nCoV from a Stool Specimen of a Laboratory-Confirmed Case of the Coronavirus Disease 2019 (COVID-19) by Zhang, Yong, Chen, Cao, Zhu, Shuangli, Shu, Chang, Wang, Dongyan, Song, Jingdong, Song, Yang, Zhen, Wei, Feng, Zijian, Wu, Guizhen, Xu, Jun, Xu, Wenbo

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Combination of oral STING agonist MSA-2 and anti-TGF-β/PD-L1 bispecific antibody YM101: a novel immune cocktail therapy for non-inflamed tumors by Yi, Ming, Niu, Mengke, Wu, Yuze, Ge, Hong, Jiao, Dechao, Zhu, Shuangli, Zhang, Jing, Yan, Yongxiang, Zhou, Pengfei, Chu, Qian, Wu, Kongming

“…Abstract Background Non-inflamed tumors, including immune-excluded and immune-desert tumors, are commonly resistant to anti-PD-1/PD-L1 (α-PD-1/PD-L1) therapy…”
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Anti-TGF-β/PD-L1 bispecific antibody promotes T cell infiltration and exhibits enhanced antitumor activity in triple-negative breast cancer by Yi, Ming, Wu, Yuze, Niu, Mengke, Zhu, Shuangli, Zhang, Jing, Yan, Yongxiang, Zhou, Pengfei, Dai, Zhijun, Wu, Kongming

“…BackgroundAgents blocking programmed cell death protein 1/programmed death-ligand 1 (PD-1/PD-L1) have been approved for triple-negative breast cancer (TNBC)…”
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MiRNA-mediated EMT and CSCs in cancer chemoresistance by Dong, Bing, Li, Shiyu, Zhu, Shuangli, Yi, Ming, Luo, Suxia, Wu, Kongming

“…Cancer stem cells (CSCs) are a small group of cancer cells, which contribute to tumorigenesis and cancer progression. Cancer cells undergoing…”
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Identification of MTHFD2 as a prognostic biomarker and ferroptosis regulator in triple-negative breast cancer by Zhang, Hao, Zhu, Shuangli, Zhou, Haiting, Li, Rui, Xia, Xiaohui, Xiong, Huihua

“…Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) is a mitochondrial bifunctional enzyme encoded in the nucleus. It plays a significant role in the regulation…”
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Persistent circulation of Coxsackievirus A6 of genotype D3 in mainland of China between 2008 and 2015 by Song, Yang, Zhang, Yong, Ji, Tianjiao, Gu, Xinrui, Yang, Qian, Zhu, Shuangli, Xu, Wen, Xu, Yi, Shi, Yong, Huang, Xueyong, Li, Qi, Deng, Hong, Wang, Xianjun, Yan, Dongmei, Yu, Wei, Wang, Shuang, Yu, Deshan, Xu, Wenbo

“…A total of 807 entire VP1 sequences of Coxsackievirus A6 (CV-A6) from mainland of China from 1992 to 2015, including 520 in this study and 287 from the GenBank…”
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An emerging recombinant human enterovirus 71 responsible for the 2008 outbreak of hand foot and mouth disease in Fuyang city of China by Zhang, Yan, Zhu, Zhen, Yang, Weizhong, Ren, Jun, Tan, Xiaojuan, Wang, Yu, Mao, Naiying, Xu, Songtao, Zhu, Shuangli, Cui, Aili, Zhang, Yong, Yan, Dongmei, Li, Qun, Dong, Xiaoping, Zhang, Jing, Zhao, Yueping, Wan, Junfeng, Feng, Zijian, Sun, Junling, Wang, Shiwen, Li, Dexin, Xu, Wenbo

“…Hand, foot and mouth disease (HFMD), a common contagious disease that usually affects children, is normally mild but can have life-threatening manifestations…”
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Focal adhesion kinase: from biological functions to therapeutic strategies by Tan, Ximin, Yan, Yuheng, Song, Bin, Zhu, Shuangli, Mei, Qi, Wu, Kongming

“…Focal adhesion kinase (FAK), a nonreceptor cytoplasmic tyrosine kinase, is a vital participant in primary cellular functions, such as proliferation, survival,…”
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Detection of multiple viruses potentially infecting humans in sewage water from Xinjiang Uygur Autonomous Region, China by Yang, Qian, Rivailler, Pierre, Zhu, Shuangli, Yan, Dongmei, Xie, Na, Tang, Haishu, Zhang, Yong, Xu, Wenbo

“…The progress of sequencing technologies has facilitated metagenomics projects on environmental samples like sewage water. The present study concerned the…”
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The prospect of combination therapies with the third-generation EGFR-TKIs to overcome the resistance in NSCLC by Li, Shiyu, Zhu, Shuangli, Wei, Hongqu, Zhu, Pengfei, Jiao, Ying, Yi, Ming, Gong, Juejun, Zheng, Kun, Zhang, Li

“…Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) bring significant benefits to non-small cell lung cancer patients with EGFR mutations,…”
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Prevalence of multiple enteroviruses associated with hand, foot, and mouth disease in Shijiazhuang City, Hebei province, China: outbreaks of coxsackieviruses a10 and b3 by Tian, Huifang, Zhang, Yong, Sun, Qiang, Zhu, Shuangli, Li, Xiujuan, Pan, Zhuo, Xu, Wenbo, Xu, Baohong

“…Hand, foot, and mouth disease (HFMD) has been one of the most common infectious diseases in Shijiazhuang City, as is the situation in China overall. In the…”
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The landscape of chimeric antigen receptor T cell therapy in breast cancer: Perspectives and outlook by Zhang, Hao, Zhu, Shuangli, Deng, Wanjun, Li, Rui, Zhou, Haiting, Xiong, Huihua

“…Chimeric antigen receptor-T (CAR-T) cell therapy is a revolutionary adoptive cell therapy, which could modify and redirect T cells to specific tumor cells…”
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