Search Results - "Zhu, Qiangyuan"
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Self-priming compartmentalization digital LAMP for point-of-care
Published in Lab on a chip (21-11-2012)“…Digital nucleic acid amplification provides unprecedented opportunities for absolute nucleic acid quantification by counting of single molecules. This…”
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Digital PCR on an integrated self-priming compartmentalization chip
Published in Lab on a chip (21-03-2014)“…An integrated on-chip valve-free and power-free microfluidic digital PCR device is for the first time developed by making use of a novel self-priming…”
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Microfluidics Facilitates the Development of Single-Cell RNA Sequencing
Published in Biosensors (Basel) (24-06-2022)“…Single-cell RNA sequencing (scRNA-seq) technology provides a powerful tool for understanding complex biosystems at the single-cell and single-molecule level…”
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Single-cell damagenome profiling unveils vulnerable genes and functional pathways in human genome toward DNA damage
Published in Science advances (02-07-2021)“…We report a novel single-cell whole-genome amplification method (LCS-WGA) that can efficiently capture spontaneous DNA damage existing in single cells. We…”
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5
Digital PCR for Single-Cell Analysis
Published in Biosensors (Basel) (01-01-2024)“…Single-cell analysis provides an overwhelming strategy for revealing cellular heterogeneity and new perspectives for understanding the biological function and…”
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CRISPR-Based Biosensors for Medical Diagnosis: Readout from Detector-Dependence Detection Toward Naked Eye Detection
Published in Biosensors (Basel) (28-07-2024)“…The detection of biomarkers (such as DNA, RNA, and protein) plays a vital role in medical diagnosis. The CRISPR-based biosensors utilize the CRISPR/Cas system…”
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A Specific and Sensitive Aptamer-Based Digital PCR Chip for Salmonella typhimurium Detection
Published in Biosensors (Basel) (26-06-2022)“…Food poisoning and infectious diseases caused by Salmonella typhimurium (S. typhimurium) are serious public health concerns for human health and food safety…”
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Spatial Omics Sequencing Based on Microfluidic Array Chips
Published in Biosensors (Basel) (06-07-2023)“…Spatial profiling technologies fill the gap left by the loss of spatial information in traditional single-cell sequencing, showing great application prospects…”
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Single-cell Damagenome Profiling by Linear Copying and Splitting based Whole Genome Amplification (LCS-WGA)
Published in Bio-protocol (20-03-2022)“…Spontaneous DNA damage frequently occurs on the human genome, and it could alter gene expression by inducing mutagenesis or epigenetic changes. Therefore, it…”
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Integrated Glass Microdevice for Nucleic Acid Purification, Loop-Mediated Isothermal Amplification, and Online Detection
Published in Analytical chemistry (Washington) (01-05-2011)“…A microdevice made of glass for genetic analysis has been fabricated, for the first time, for integration of extraction of nucleic acids and loop-mediated…”
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Single cell digital polymerase chain reaction on self-priming compartmentalization chip
Published in Biomicrofluidics (01-01-2017)“…Single cell analysis provides a new framework for understanding biology and disease, however, an absolute quantification of single cell gene expression still…”
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Glucose-driven transformable complex eliminates biofilm and alleviates inflamm-aging for diabetic periodontitis therapy
Published in Materials today bio (01-06-2023)“…Diabetic periodontitis is a major complication of diabetes, which has a deep involvement in teeth loss and more serious systematic diseases, including…”
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13
Extremal k‐uniform hypertrees on incidence energy
Published in International journal of quantum chemistry (05-05-2021)“…For a k‐uniform hypergraph H = (V(H), E(H)), let B(H) be its incidence matrix, Q(H) = B(H)B(H)T be its signless Laplacian matrix. Let S(H) be the subdivision…”
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Droplet-based transcriptome profiling of individual synapses
Published in Nature biotechnology (01-09-2023)“…Synapses are crucial structures that mediate signal transmission between neurons in complex neural circuits and display considerable morphological and…”
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A new method for polydimethylsiloxane (PDMS) microfluidic chips to maintain vacuum-driven power using Parylene C
Published in Sensors and actuators. B, Chemical (01-03-2018)“…•Extend the working time of the vacuum-driven microfluidics from 1day to 30days.•Biochemical detections won’t be influenced in the Parylene C-coated chips.•The…”
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A scalable self-priming fractal branching microchannel net chip for digital PCR
Published in Lab on a chip (07-05-2017)“…As an absolute quantification method at the single-molecule level, digital PCR has been widely used in many bioresearch fields, such as next generation…”
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A fully automatic dPCR microfluidic system for detection of large-volume and low-abundance bacteria sample
Published in Sensors and actuators. B, Chemical (15-04-2024)“…Digital polymerase chain reaction (dPCR) has become a key technology for bacteria detection with superior sensitivity and accuracy, enabling in reducing the…”
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Mixed-Dye-Based Label-Free and Sensitive Dual Fluorescence for the Product Detection of Nucleic Acid Isothermal Multiple-Self-Matching-Initiated Amplification
Published in Analytical chemistry (Washington) (20-10-2015)“…Visual detections based on fluorescence and the color changes under natural light are two promising product detections for isothermal nucleic acid…”
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Co-detection of ALDH1A1, ABCG2, ALCAM and CD133 in three A549 subpopulations at the single cell level by one-step digital RT-PCR
Published in Integrative biology (Cambridge) (18-06-2018)“…Cancer stem-like cells (CSCs) displaying the properties of normal stem cells have become the main culprit associated with cancer transportation and recurrence…”
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Co-detection of ALDH1A1, ABCG2, ALCAM and CD133 in three A549 subpopulations at the single cell level by one-step digital RT-PCRElectronic supplementary information (ESI) available. See DOI: 10.1039/c8ib00042e
Published 18-06-2018“…Cancer stem-like cells (CSCs) displaying the properties of normal stem cells have become the main culprit associated with cancer transportation and recurrence…”
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