Search Results - "Zhu, Nian–Ling"
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Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice
Published in Hepatology (Baltimore, Md.) (01-01-2015)“…Alcoholic hepatitis (AH) is a distinct spectrum of alcoholic liver disease (ALD) with intense neutrophilic (polymorphonuclear; PMN) inflammation and high…”
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2
MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis
Published in Gastroenterology (New York, N.Y. 1943) (01-02-2010)“…Background & Aims Myofibroblast transdifferentiation generates hepatic myofibroblasts, which promote liver fibrogenesis. The peroxisome proliferator-activated…”
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3
Epigenetic cell fate regulation of hepatic stellate cells
Published in Hepatology research (01-07-2011)“…Research in the past three decades has identified key mediators and signaling mechanisms responsible for myofibroblastic transdifferentiation (MTD) of hepatic…”
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4
Morphogens and hepatic stellate cell fate regulation in chronic liver disease
Published in Journal of gastroenterology and hepatology (01-03-2012)“…Hepatic stellate cells (HSC) are the liver mesenchymal cell type which responds to hepatocellular damage and participates in wound healing. Although HSC…”
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5
Hepatic Stellate Cell-derived Delta-like Homolog 1 (DLK1) Protein in Liver Regeneration
Published in The Journal of biological chemistry (23-03-2012)“…Hepatic stellate cells (HSCs) undergo myofibroblastic activation in liver fibrosis and regeneration. This phenotypic switch is mechanistically similar to…”
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6
The Necdin-Wnt Pathway Causes Epigenetic Peroxisome Proliferator-activated Receptor γ Repression in Hepatic Stellate Cells
Published in The Journal of biological chemistry (01-10-2010)“…Hepatic stellate cells (HSCs), vitamin A-storing liver pericytes, undergo myofibroblastic trans-differentiation or “activation” to participate in liver wound…”
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7
Timeless in lung morphogenesis
Published in Developmental dynamics (01-09-2003)“…The Clock gene, timeless, regulates circadian rhythm in Drosophila, but its vertebrate homolog is critical to embryonic development. Timeless was shown to be…”
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8
Retargeting of adenoviral vector using basic fibroblast growth factor ligand for malignant glioma gene therapy
Published in Journal of neurosurgery (01-12-2005)“…Adenovirus vector (AdV)-mediated gene delivery has been recently demonstrated in clinical trials as a novel potential treatment for malignant gliomas. Combined…”
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9
Physical and Functional Interactions between Homeodomain NKX2.1 and Winged Helix/Forkhead FOXA1 in Lung Epithelial Cells
Published in Molecular and Cellular Biology (01-03-2007)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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10
Mutational Analysis of the Fusion Peptide of Moloney Murine Leukemia Virus Transmembrane Protein p15E
Published in Journal of Virology (01-02-1998)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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11
TNF-alpha represses transcription of human Bone Morphogenetic Protein-4 in lung epithelial cells
Published in Gene (15-05-2007)“…Bone Morphogenetic Proteins are key signaling molecules in vertebrate development. Little is known about Bmp gene regulation in any organ. In Drosophila, the…”
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12
Transforming Growth Factor-β Inhibits Pulmonary Surfactant Protein B Gene Transcription through SMAD3 Interactions with NKX2.1 and HNF-3 Transcription Factors
Published in The Journal of biological chemistry (11-10-2002)“…Transforming growth factor-β (TGF-β) represses surfactant protein B (Sp-B) gene transcription through a mechanism that remains unknown. A homeodomain and a…”
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13
NKX2.1 regulates transcription of the gene for human bone morphogenetic protein-4 in lung epithelial cells
Published in Gene (18-02-2004)“…Bone morphogenetic protein 4, BMP4, plays an important role in the development of various organs including the lungs. Little is known regarding the regulation…”
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14
Molecular engineering of matrix-targeted retroviral vectors incorporating a surveillance function inherent in von Willebrand factor
Published in Human gene therapy (01-05-2000)“…A major obstacle that limits the potential of human gene therapy is the inefficiency of gene delivery to appropriate sites in vivo. Previous studies…”
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15
Downregulation of cyclin G1 expression by retrovirus-mediated antisense gene transfer inhibits vascular smooth muscle cell proliferation and neointima formation
Published in Circulation (New York, N.Y.) (15-07-1997)“…The contemporary treatment of coronary athero-occlusive disease by percutaneous transluminal coronary angioplasty is hampered by maladaptive wound healing,…”
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16
Retroviral vector-mediated transfer of an antisense cyclin G1 construct inhibits osteosarcoma tumor growth in nude mice
Published in Human gene therapy (20-09-1997)“…Metastatic osteosarcoma is a potential target for gene therapy, because conventional therapies are only palliative and metastatic disease is invariably fatal…”
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17
Lesion-targeted injectable vectors for vascular restenosis
Published in Human gene therapy (01-07-2001)“…Pathologic lesions caused by catheter-based revascularization procedures for occlusive artery disease include disruption of the endothelium, exposure of…”
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18
The Necdin-Wnt Pathway Causes Epigenetic Peroxisome Proliferator-activated Receptor g Repression in Hepatic Stellate Cells
Published in The Journal of biological chemistry (01-10-2010)“…Hepatic stellate cells (HSCs), vitamin A-storing liver pericytes, undergo myofibroblastic trans-differentiation or 'activationa to participate in liver wound…”
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19
Transforming Growth Factor-β Inhibits Pulmonary Surfactant Protein B Gene Transcription through SMAD3 Interactions with NKX2.1 and HNF-3 Transcription Factors
Published in The Journal of biological chemistry (11-10-2002)“…Transforming growth factor-β (TGF-β) represses surfactant protein B ( Sp-B ) gene transcription through a mechanism that remains unknown. A homeodomain and a…”
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20
Targeting retroviral vectors to vascular lesions by genetic engineering of the MoMLV gp70 envelope protein
Published in Human gene therapy (10-12-1997)“…Targeted gene delivery to vascular lesions is a major challenge in the development of gene therapy protocols for cardiovascular diseases. One approach would be…”
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