Search Results - "Zhu, Mei J"

Maternal Obesity, Inflammation, and Fetal Skeletal Muscle Development by Du, Min, Yan, Xu, Tong, Jun F, Zhao, Junxing, Zhu, Mei J

“…Maternal obesity coupled with Western-style high-energy diets represents a special problem that can result in poor fetal development, leading to harmful,…”
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Maternal obesity markedly increases placental fatty acid transporter expression and fetal blood triglycerides at midgestation in the ewe by Zhu, Mei J, Ma, Yan, Long, Nathan M, Du, Min, Ford, Stephen P

“…Obesity of women at conception is increasing, a condition associated with offspring obesity. We hypothesized that maternal obesity increases placental fatty…”
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Maternal nutrient restriction affects properties of skeletal muscle in offspring by Zhu, Mei J., Ford, Stephen P., Means, Warrie J., Hess, Bret W., Nathanielsz, Peter W., Du, Min

“…Maternal nutrient restriction (NR) affects fetal development with long-term consequences on postnatal health of offspring, including predisposition to obesity…”
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AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes by Tong, Jun F., Yan, Xu, Zhu, Mei J., Du, Min

“…Two muscle‐specific ubiquitin ligases (UL), muscle atrophy F box (MAFbx) and muscle RING finger 1 (MuRF1), are crucial for myofibrillar protein breakdown. The…”
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AMP-activated protein kinase signalling pathways are down regulated and skeletal muscle development impaired in fetuses of obese, over-nourished sheep by Zhu, Mei J., Han, Bin, Tong, Junfeng, Ma, Changwei, Kimzey, Jessica M., Underwood, Keith R., Xiao, Yao, Hess, Bret W., Ford, Stephen P., Nathanielsz, Peter W., Du, Min

“…Maternal obesity and over-nutrition give rise to both obstetric problems and neonatal morbidity. The objective of this study was to evaluate effects of…”
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Rat hindlimb unloading down-regulates insulin like growth factor-1 signaling and AMP-activated protein kinase, and leads to severe atrophy of the soleus muscle by Han, Bing, Zhu, Mei J, Ma, Changwei, Du, Min

“…Inactivity is known to induce muscle atrophy, which is associated with insulin and insulin-like growth factor-1 (IGF-1) resistance, but the associated…”
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Cellular signaling pathways regulating the initial stage of adipogenesis and marbling of skeletal muscle by Du, Min, Yin, Jingdong, Zhu, Mei J.

“…Due to extensive efforts to increase lean growth, intramuscular fat (marbling) is reducing in beef, pork and chicken breast, which impairs the eating quality…”
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AMP-activated protein kinase (AMPK) cross-talks with canonical Wnt signaling via phosphorylation of β-catenin at Ser 552 by Zhao, Junxing, Yue, Wanfu, Zhu, Mei J., Sreejayan, Nair, Du, Min

“…AMP-activated protein kinase (AMPK) is a key regulator of energy metabolism; its activity is regulated by a plethora of physiological conditions, exercises and…”
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Angiotensin II promotes smooth muscle cell proliferation and migration through release of heparin-binding epidermal growth factor and activation of EGF-receptor pathway by Yang, Xiaoping, Zhu, Mei J, Sreejayan, N, Ren, J, Du, Min

“…Transactivation of EGF-receptor (EGFR) by G-protein coupled receptors (GPCRs) is emerging as an important pathway in cell proliferation, which plays a crucial…”
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Maternal obesity downregulates myogenesis and beta-catenin signaling in fetal skeletal muscle by Tong, Jun F, Yan, Xu, Zhu, Mei J, Ford, Stephen P, Nathanielsz, Peter W, Du, Min

“…Skeletal muscle is one of the primary tissues responsible for insulin resistance and type 2 diabetes (T2D). The fetal stage is crucial for skeletal muscle…”
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Up-Regulation of Toll-Like Receptor 4/Nuclear Factor-κB Signaling Is Associated with Enhanced Adipogenesis and Insulin Resistance in Fetal Skeletal Muscle of Obese Sheep at Late Gestation by Yan, Xu, Zhu, Mei J, Xu, Wei, Tong, Jun F, Ford, Stephen P, Nathanielsz, Peter W, Du, Min

“…Maternal obesity is increasing at an alarming rate. We previously showed that maternal obesity induces an inflammatory response and enhances adipogenesis in…”
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Ca2+/calmodulin-dependent protein kinase kinase is involved in AMP-activated protein kinase activation by alpha-lipoic acid in C2C12 myotubes by Shen, Qingwu W, Zhu, Mei J, Tong, Junfeng, Ren, Jun, Du, Min

“…alpha-Lipoic acid (ALA) widely exists in foods and is an antidiabetic agent. ALA stimulates glucose uptake and increases insulin sensitivity by the activation…”
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Maternal obesity induces fibrosis in fetal myocardium of sheep by Huang, Yan, Yan, Xu, Zhao, Jun X, Zhu, Mei J, McCormick, Richard J, Ford, Stephen P, Nathanielsz, Peter W, Ren, Jun, Du, Min

“…Maternal obesity (MO) has harmful effects on both fetal development and subsequent offspring health. The impact of MO on fetal myocardium development has…”
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Maternal obesity and overnutrition alter fetal growth rate and cotyledonary vascularity and angiogenic factor expression in the ewe by Ma, Yan, Zhu, Mei J, Zhang, Liren, Hein, Sarah M, Nathanielsz, Peter W, Ford, Stephen P

“…In pregnant sheep, maternal:fetal exchange occurs across placentomes composed of placental cotyledonary and uterine caruncular tissues. Recently, we reported…”
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Insulin-like growth factor-1 (IGF-1) and leucine activate pig myogenic satellite cells through mammalian target of rapamycin (mTOR) pathway by Han, Bing, Tong, Junfeng, Zhu, Mei J., Ma, Changwei, Du, Min

“…Myogenic satellite cells are adult stem cells and have important roles in skeletal muscle growth, repair, and regeneration. Both insulin‐like growth factor‐1…”
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Enhanced transforming growth factor-beta signaling and fibrogenesis in ovine fetal skeletal muscle of obese dams at late gestation by Huang, Yan, Yan, Xu, Zhu, Mei J, McCormick, Richard J, Ford, Stephen P, Nathanielsz, Peter W, Du, Min

“…Maternal obesity (MO) is increasing at an alarming rate. The objective of this study was to evaluate the effect of MO on fibrogenesis in fetal skeletal muscle…”
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Early Post-mortem AMP-Activated Protein Kinase (AMPK) Activation Leads to Phosphofructokinase-2 and -1 (PFK-2 and PFK-1) Phosphorylation and the Development of Pale, Soft, and Exudative (PSE) Conditions in Porcine Longissimus Muscle by Shen, Qingwu W, Means, Warrie J, Underwood, Keith R, Thompson, Shane A, Zhu, Mei J, McCormick, Richard J, Ford, Stephen P, Ellis, Mickel, Du, Min

“…Pale, soft, and exudative (PSE) meat has been recognized for decades. Fast glycolysis during early post-mortem stage while the muscle temperature is still high…”
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Maternal Obesity, Inflammation, and Fetal Skeletal Muscle Development1 by Du, Min, Yan, Xu, Tong, Jun F, Zhao, Junxing, Zhu, Mei J

“…Maternal obesity coupled with Western-style high-energy diets represents a special problem that can result in poor fetal development, leading to harmful,…”
Get full text

Relationship between Kinase Phosphorylation, Muscle Fiber Typing, and Glycogen Accumulation in Longissimus Muscle of Beef Cattle with High and Low Intramuscular Fat by Underwood, Keith R, Tong, Junfeng, Zhu, Mei J, Shen, Qingwu W, Means, Warrie J, Ford, Stephen P, Paisley, Steven I, Hess, Bret W, Du, Min

“…The objective of this study was to examine the association of adenosine monophosphate (AMP)-activated protein kinase (AMPK) with glycogen content in bovine…”
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Role of β-Adrenoceptor Signaling and AMP-Activated Protein Kinase in Glycolysis of Postmortem Skeletal Muscle by Du, Min, Shen, Qingwu W, Zhu, Mei J

“…Postmortem glycolysis is directly linked to the incidences of PSE (pale, soft, and exudative) and DFD (dark, firm, and dry) meats, which cause significant…”
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