Search Results - "Zhu, Lucía"

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    Incidental pulmonary nodule management in Canada: exploring current state through a narrative literature review and expert interviews by Digby, Geneviève C, Habert, Jeffrey, Sahota, Jyoti, Zhu, Lucía, Manos, Daria

    Published in Journal of thoracic disease (29-02-2024)
    “…Incidental pulmonary nodules (IPNs) are common and increasingly detected with the overall rise of radiologic imaging. Effective IPN management is necessary to…”
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    Journal Article
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    Protocol to generate murine organotypic brain cultures for drug screening and evaluation of anti-metastatic efficacy by Zhu, Lucía, Miarka, Lauritz, Baena, Patricia, Perea-García, María, Valiente, Manuel

    Published in STAR protocols (16-06-2023)
    “…Organotypic brain cultures are short-term assays that phenotypically and functionally recapitulate brain metastatic cells in vivo. Here, we present a protocol…”
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    Dianhydrogalactitol Overcomes Multiple Temozolomide Resistance Mechanisms in Glioblastoma by Jiménez-Alcázar, Miguel, Curiel-García, Álvaro, Nogales, Paula, Perales-Patón, Javier, Schuhmacher, Alberto J, Galán-Ganga, Marcos, Zhu, Lucía, Lowe, Scott W, Al-Shahrour, Fátima, Squatrito, Massimo

    Published in Molecular cancer therapeutics (01-06-2021)
    “…Glioblastoma (GBM) is the most frequent and aggressive primary tumor type in the central nervous system in adults. Resistance to chemotherapy remains one of…”
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    Human Tear Fluid Reduces Culturability of Contact Lens Associated Pseudomonas aeruginosa Biofilms but Induces Expression of the Virulence Associated Type III Secretion System by Wu, Yvonne T., OD, PhD, Tam, Connie, PhD, Zhu, Lucia S., BA, Evans, David J., PhD, Fleiszig, Suzanne M.J., OD, PhD

    Published in The ocular surface (01-01-2017)
    “…Abstract Purpose The type III secretion system (T3SS) is a significant virulence determinant for Pseudomonas aeruginosa . Using a rodent model, we found that…”
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    Pseudomonas aeruginosa Survival at Posterior Contact Lens Surfaces after Daily Wear by Wu, Yvonne T, Zhu, Lucia S, Tam, K. P Connie, Evans, David J, Fleiszig, Suzanne M J

    Published in Optometry and vision science (01-06-2015)
    “…PURPOSEPseudomonas aeruginosa keratitis is a sight-threatening complication of contact lens wear, yet mechanisms by which lenses predispose to infection remain…”
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    Transcriptomic Hallmarks of Tumor Plasticity and Stromal Interactions in Brain Metastasis by Wingrove, Emily, Liu, Zongzhi Z., Patel, Kiran D., Arnal-Estapé, Anna, Cai, Wesley L., Melnick, Mary-Ann, Politi, Katerina, Monteiro, Cátia, Zhu, Lucía, Valiente, Manuel, Kluger, Harriet M., Chiang, Veronica L., Nguyen, Don X.

    Published in Cell reports (Cambridge) (23-04-2019)
    “…The brain is a major site of relapse for several cancers, yet deciphering the mechanisms of brain metastasis remains a challenge because of the complexity of…”
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    Transcriptomic Hallmarks of Tumor Plasticity and Stromal Interactions in Brain Metastasis by Wingrove, Emily, Liu, Zongzhi Z, Patel, Kiran D, Arnal‐Estape, Anna, Melnick, Mary‐Ann, Politi, Katerina, Monteiro, Cátia, Zhu, Lucía, Valiente, Manuel, Kluger, Harriet M, Chiang, Veronica L, Nguyen, Don X

    Published in The FASEB journal (01-04-2019)
    “…Purpose Brain metastasis remains a major site of relapse for several cancer types. However, the molecular mechanisms of brain metastasis are largely unknown…”
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    A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis by Zhu, Lucía, Retana, Diana, García‐Gómez, Pedro, Álvaro‐Espinosa, Laura, Priego, Neibla, Masmudi‐Martín, Mariam, Yebra, Natalia, Miarka, Lauritz, Hernández‐Encinas, Elena, Blanco‐Aparicio, Carmen, Martínez, Sonia, Sobrino, Cecilia, Ajenjo, Nuria, Artiga, Maria‐Jesus, Ortega‐Paino, Eva, Torres‐Ruiz, Raúl, Rodríguez‐Perales, Sandra, Soffietti, Riccardo, Bertero, Luca, Cassoni, Paola, Weiss, Tobias, Muñoz, Javier, Sepúlveda, Juan Manuel, González‐León, Pedro, Jiménez‐Roldán, Luis, Moreno, Luis Miguel, Esteban, Olga, Pérez‐Núñez, Ángel, Hernández‐Laín, Aurelio, Toldos, Oscar, Ruano, Yolanda, Alcázar, Lucía, Blasco, Guillermo, Fernández‐Alén, José, Caleiras, Eduardo, Lafarga, Miguel, Megías, Diego, Graña‐Castro, Osvaldo, Nör, Carolina, Taylor, Michael D, Young, Leonie S, Varešlija, Damir, Cosgrove, Nicola, Couch, Fergus J, Cussó, Lorena, Desco, Manuel, Mouron, Silvana, Quintela‐Fandino, Miguel, Weller, Michael, Pastor, Joaquín, Valiente, Manuel, de la Lama‐Zaragoza, Adolfo, Calero‐Felix, Lourdes, Fiaño‐Valverde, Concepcion, Delgado‐López, Pedro David, Montalvo‐Afonso, Antonio, Pascual‐Llorente, Mar, Díaz‐Piqueras, Ángela, Nam‐Cha, SH, Barrena López, Cristina, Plans Ahicart, Gerard, Martínez‐Saez, Elena, Ramón y Cajal, Santiago, Nicolás, Pilar

    Published in EMBO molecular medicine (07-03-2022)
    “…We report a medium‐throughput drug‐screening platform (METPlatform) based on organotypic cultures that allows to evaluate inhibitors against metastases growing…”
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    BSCI-02. METPlatform identifies brain metastasis vulnerabilities and predicts patient response to therapy by Zhu, Lucía, Blanco-Aparicio, Carmen, Bertero, Luca, Soffietti, Riccardo, Weiss, Tobias, Muñoz, Javier, Sepúlveda, Juan Manuel, Weller, Michael, Pastor, Joaquín, Valiente, Manuel

    Published in Neuro-oncology advances (09-08-2021)
    “…Abstract The diagnosis of brain metastasis involves high morbidity and mortality and remains an unmet clinical need in spite of being the most common tumor in…”
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    Impact of topical corticosteroid pretreatment on susceptibility of the injured murine cornea to Pseudomonas aeruginosa colonization and infection by Wu, Yvonne T., Truong, Tan N., Tam, Connie, Mendoza, Myra N., Zhu, Lucia, Evans, David J., Fleiszig, Suzanne M.J.

    Published in Experimental eye research (01-02-2019)
    “…Research with animal models of Pseudomonas aeruginosa keratitis has shown that use of a topical corticosteroid alone against an established infection can…”
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