Search Results - "Zhu, Lucía"
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1
STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis
Published in Nature medicine (01-07-2018)“…The brain microenvironment imposes a particularly intense selective pressure on metastasis-initiating cells, but successful metastases bypass this control…”
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2
Incidental pulmonary nodule management in Canada: exploring current state through a narrative literature review and expert interviews
Published in Journal of thoracic disease (29-02-2024)“…Incidental pulmonary nodules (IPNs) are common and increasingly detected with the overall rise of radiologic imaging. Effective IPN management is necessary to…”
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3
Protocol to generate murine organotypic brain cultures for drug screening and evaluation of anti-metastatic efficacy
Published in STAR protocols (16-06-2023)“…Organotypic brain cultures are short-term assays that phenotypically and functionally recapitulate brain metastatic cells in vivo. Here, we present a protocol…”
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Impact of poor medication adherence on clinical outcomes and health resource utilization in patients with hypertension and/or dyslipidemia: systematic review
Published in Expert review of pharmacoeconomics & outcomes research (2024)“…We aimed to summarize evidence on the effect of poor medication adherence on clinical outcomes and health resource utilization (HRU) among patients with…”
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5
Dianhydrogalactitol Overcomes Multiple Temozolomide Resistance Mechanisms in Glioblastoma
Published in Molecular cancer therapeutics (01-06-2021)“…Glioblastoma (GBM) is the most frequent and aggressive primary tumor type in the central nervous system in adults. Resistance to chemotherapy remains one of…”
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6
Growth exponents reflect evolutionary processes and treatment response in brain metastases
Published in NPJ systems biology and applications (21-07-2023)“…Tumor growth is the result of the interplay of complex biological processes in huge numbers of individual cells living in changing environments. Effective…”
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Abstract 2746: Stat3 labels a subpopulation of reactive astrocytes required for brain metastasis
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract The diagnosis of brain metastasis involves high morbidity and mortality and remains as an unmet clinical need in spite of being the most common tumor…”
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Human Tear Fluid Reduces Culturability of Contact Lens Associated Pseudomonas aeruginosa Biofilms but Induces Expression of the Virulence Associated Type III Secretion System
Published in The ocular surface (01-01-2017)“…Abstract Purpose The type III secretion system (T3SS) is a significant virulence determinant for Pseudomonas aeruginosa . Using a rodent model, we found that…”
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Pseudomonas aeruginosa Survival at Posterior Contact Lens Surfaces after Daily Wear
Published in Optometry and vision science (01-06-2015)“…PURPOSEPseudomonas aeruginosa keratitis is a sight-threatening complication of contact lens wear, yet mechanisms by which lenses predispose to infection remain…”
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10
Universal scaling laws rule explosive growth in human cancers
Published in Nature physics (01-12-2020)“…Most physical and other natural systems are complex entities that are composed of a large number of interacting individual elements. It is a surprising fact…”
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Transcriptomic Hallmarks of Tumor Plasticity and Stromal Interactions in Brain Metastasis
Published in Cell reports (Cambridge) (23-04-2019)“…The brain is a major site of relapse for several cancers, yet deciphering the mechanisms of brain metastasis remains a challenge because of the complexity of…”
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Transcriptomic Hallmarks of Tumor Plasticity and Stromal Interactions in Brain Metastasis
Published in The FASEB journal (01-04-2019)“…Purpose Brain metastasis remains a major site of relapse for several cancer types. However, the molecular mechanisms of brain metastasis are largely unknown…”
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A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis
Published in EMBO molecular medicine (07-03-2022)“…We report a medium‐throughput drug‐screening platform (METPlatform) based on organotypic cultures that allows to evaluate inhibitors against metastases growing…”
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Author Correction: STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis
Published in Nature medicine (01-09-2018)“…In the version of this article originally published, the names of three authors were incorrect. The authors were listed as “Coral Fustero-Torres”, “Elena…”
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BSCI-02. METPlatform identifies brain metastasis vulnerabilities and predicts patient response to therapy
Published in Neuro-oncology advances (09-08-2021)“…Abstract The diagnosis of brain metastasis involves high morbidity and mortality and remains an unmet clinical need in spite of being the most common tumor in…”
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42. IDENTIFICATION OF BRAIN METASTASIS VULNERABILITIES USING METPLATFORM
Published in Neuro-oncology advances (04-08-2020)“…Abstract The diagnosis of brain metastasis involves high morbidity and mortality and remains an unmet clinical need in spite of being the most common tumor in…”
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17
Pseudomonas aeruginosa Survival at Posterior Contact Lens Surfaces after Daily Wear
Published in Optometry and vision science (01-06-2015)Get full text
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18
Impact of topical corticosteroid pretreatment on susceptibility of the injured murine cornea to Pseudomonas aeruginosa colonization and infection
Published in Experimental eye research (01-02-2019)“…Research with animal models of Pseudomonas aeruginosa keratitis has shown that use of a topical corticosteroid alone against an established infection can…”
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19
Universal scaling laws rule explosive growth inhuman cancers
Published 22-04-2021“…Nat.Phys. 16 (2020) 1232-1237 Most physical and other natural systems are complex entities composed of a large number of interacting individual elements. It is…”
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