Search Results - "Zhu, Linyan"
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Progress in research on paclitaxel and tumor immunotherapy
Published in Cellular & molecular biology letters (13-06-2019)“…Paclitaxel is a well-known anticancer agent with a unique mechanism of action. It is considered to be one of the most successful natural anticancer drugs…”
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Aptly chosen, effectively emphasizing the action and mechanism of antimycin A1
Published in Frontiers in microbiology (03-04-2024)“…Rhizoctonia solani Kühn, a plant pathogenic fungus that can cause diseases in multiple plant species is considered one of the common and destructive pathogens…”
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Prenatal detection of novel compound heterozygous variants of the PLD1 gene in a fetus with congenital heart disease
Published in Frontiers in genetics (01-11-2024)“…Background Congenital heart disease (CHD) is the most common birth defect and heart valve defects are the most common cardiac defect, accounting for over 25%…”
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Research on Optimal Design of Civil Sensors Based on Agglomerative Hierarchical Clustering Algorithm
Published in Tehnički vjesnik (01-10-2024)“…In practical engineering, the sensor measurement points will have obvious clustering characteristics. Therefore, the cohesive hierarchical clustering algorithm…”
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Retrieval of Atmospheric Water Vapor Content in the Environment from AHI/H8 Using Both Physical and Random Forest Methods—A Case Study for Typhoon Maria (201808)
Published in Remote sensing (Basel, Switzerland) (01-01-2023)“…The advanced imagers onboard the new generation of geostationary satellites could provide multilayer atmospheric moisture information with unprecedented high…”
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NORMAN guidance on suspect and non-target screening in environmental monitoring
Published in Environmental sciences Europe (04-09-2023)“…Increasing production and use of chemicals and awareness of their impact on ecosystems and humans has led to large interest for broadening the knowledge on the…”
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ClC-3 promotes paclitaxel resistance via modulating tubulins polymerization in ovarian cancer cells
Published in Biomedicine & pharmacotherapy (01-06-2021)“…Epithelial ovarian cancers (EOC) present as malignant tumors with high mortality in the female reproductive system diseases. Acquired resistance to paclitaxel…”
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Antitumor effects of disulfiram/copper complex in the poorly-differentiated nasopharyngeal carcinoma cells via activating ClC-3 chloride channel
Published in Biomedicine & pharmacotherapy (01-12-2019)“…The enhancement of the anticancer activity by disulfiram (DSF) chelated with copper (DSF/Cu2+) has been investigated recently, while the underlying molecular…”
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Limb girdle muscular dystrophy 23 caused by compound heterozygous mutations of LAMA2 gene
Published in Frontiers in pediatrics (19-06-2023)“…Mutations of gene are associated with congenital muscular dystrophy (CMD). The -related CMD mainly consists of two diseases, merosin deficient congenital…”
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Mechano-regulation of GLP-1 production by Piezo1 in intestinal L cells
Published in eLife (07-11-2024)“…Glucagon-like peptide 1 (GLP-1) is a gut-derived hormone secreted by intestinal L cells and vital for postprandial glycemic control. As open-type…”
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The selective cytotoxicity of DSF-Cu attributes to the biomechanical properties and cytoskeleton rearrangements in the normal and cancerous nasopharyngeal epithelial cells
Published in The international journal of biochemistry & cell biology (01-03-2017)“…Cancer initiation and progression follow complex changes of cellular architecture and biomechanical property. Cancer cells with more submissive (or “softer”)…”
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MiR-486-5p Act as a Biomarker in Endometrial Carcinoma: Promotes Cell Proliferation, Migration, Invasion by Targeting MARK1
Published in OncoTargets and therapy (01-01-2020)“…miRNA expression acts as a potential biomarker in many diseases including endometrial carcinoma (EC). miR-486-5p dysregulation is observed in several tumor…”
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Overview of the structure-based non-genomic effects of the nuclear receptor RXRα
Published in Cellular & molecular biology letters (07-08-2018)“…The nuclear receptor RXRα (retinoid X receptor-α) is a transcription factor that regulates the expression of multiple genes. Its non-genomic function is…”
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What is in the fish? Collaborative trial in suspect and non-target screening of organic micropollutants using LC- and GC-HRMS
Published in Environment international (01-11-2023)“…[Display omitted] •Collaborative trial of 16 laboratories on suspect and non-target screening (NTS) in fish.•Comparison of test extracts by in-house and…”
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A chloride channel in rat pancreatic acinar AR42J cells is sensitive to extracellular acidification and dependent on ROS
Published in Biochemical and biophysical research communications (04-06-2020)“…Extracellular acidification, playing a promoting role in the process of acute pancreatitis, has been reported to activate Cl− channels in several types of…”
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Case report: A compound heterozygous mutations in ASNS broadens the spectrum of asparagine synthetase deficiency in the prenatal diagnosis
Published in Frontiers in pediatrics (13-10-2023)“…Asparagine synthetase deficiency (ASNSD) is a rare congenital disorder characterized by severe progressive microcephaly, global developmental delay, spastic…”
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Genomic characterization of Chinese ovarian clear cell carcinoma identifies driver genes by whole exome sequencing
Published in Neoplasia (New York, N.Y.) (01-09-2020)“…Little is known about the genetic alterations characteristic of ovarian clear cell carcinoma (OCCC). Our aim was to identify targetable genomic alterations in…”
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Multiomics analysis of homologous recombination deficiency across cancer types
Published in Biomolecules & biomedicine (28-07-2024)“…There remains ongoing debate regarding the association of homologous recombination deficiency (HRD) with patient survival across various malignancies,…”
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Differential expression and roles of volume-activated chloride channels in control of growth of normal and cancerous nasopharyngeal epithelial cells
Published in Biochemical pharmacology (01-02-2012)“…We have previously shown that chloride channel activities were cell cycle-dependent and were involved in cell proliferation in nasopharyngeal carcinoma cells…”
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CTHRC1 is associated with BRAF (V600E) mutation and correlates with prognosis, immune cell infiltration, and drug resistance in colon cancer, thyroid cancer, and melanoma
Published in Biomolecules & biomedicine (23-07-2024)“…Colon cancer, thyroid cancer, and melanoma are common malignant tumors that seriously threaten human health globally. The B-Raf proto-oncogene,…”
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