Search Results - "Zhu, Jieping"

Construction of Quaternary Stereocenters by Palladium‐Catalyzed Carbopalladation‐Initiated Cascade Reactions by Ping, Yuanyuan, Li, Yuxiu, Zhu, Jieping, Kong, Wangqing

“…The enantioselective synthesis of molecules containing quaternary stereocenters is a field of intense research interest and development. Among the known…”
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Copper-catalyzed remote C(sp3)–H azidation and oxidative trifluoromethylation of benzohydrazides by Bao, Xu, Wang, Qian, Zhu, Jieping

“…The Hofmann-Löffler-Freytag (HLF) reaction is a prototypical example of radical-based remote functionalization of unactivated C( sp 3 )–H bond. While…”
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Dual Photoredox/Copper Catalysis for the Remote C(sp3)−H Functionalization of Alcohols and Alkyl Halides by N‐Alkoxypyridinium Salts by Bao, Xu, Wang, Qian, Zhu, Jieping

“…Under mild dual photoredox/copper catalysis, the reaction of N‐alkoxypyridinium salts with readily available silyl reagents (TMSN3, TMSCN, TMSNCS) afforded…”
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Copper‐Catalyzed Arylation of Remote C(sp3)−H Bonds in Carboxamides and Sulfonamides by Li, Zhaodong, Wang, Qian, Zhu, Jieping

“…Reported herein is an unprecedented copper‐catalyzed arylation of remote C(sp3)−H bonds. Stirring a trifluorotoluene solution of either N‐fluorocarboxamides or…”
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Water as a Hydride Source in Palladium‐Catalyzed Enantioselective Reductive Heck Reactions by Kong, Wangqing, Wang, Qian, Zhu, Jieping

“…Pd‐catalyzed intramolecular asymmetric carbopalladation of N‐aryl acrylamides followed by reduction of C(sp3)‐Pd intermediate using diboron–water as a hydride…”
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Unified divergent strategy towards the total synthesis of the three sub-classes of hasubanan alkaloids by Li, Guang, Wang, Qian, Zhu, Jieping

“…Elegant asymmetric synthesis of hasubanan alkaloids have been developed over the past decades. However, a divergent approach leading to all three sub-classes…”
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Palladium-Catalyzed Enantioselective Domino Heck/Intermolecular C–H Bond Functionalization: Development and Application to the Synthesis of (+)-Esermethole by Kong, Wangqing, Wang, Qian, Zhu, Jieping

“…Intramolecular asymmetric carbopalladation of N-aryl acrylamides followed by intermolecular trapping of the resulting σ-C­(sp3)–Pd complex by azoles afforded…”
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Asymmetric Total Synthesis of (−)-Arborisidine and (−)-19-epi-Arborisidine Enabled by a Catalytic Enantioselective Pictet–Spengler Reaction by Andres, Rémi, Wang, Qian, Zhu, Jieping

“…A five-step total synthesis of arborisidine, a caged pentacyclic monoterpene indole alkaloid, has been accomplished in both racemic and enantioselective…”
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Catalytic Enantioselective Pinacol and Meinwald Rearrangements for the Construction of Quaternary Stereocenters by Wu, Hua, Wang, Qian, Zhu, Jieping

“…The development of enantioselective pinacol rearrangement is extremely challenging due to the likelihood involvement of the carbenium intermediate that renders…”
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Palladium‐Catalyzed Enantioselective Narasaka–Heck Reaction/Direct C−H Alkylation of Arenes: Iminoarylation of Alkenes by Bao, Xu, Wang, Qian, Zhu, Jieping

“…A palladium‐catalyzed reaction of γ,δ‐unsaturated oxime esters with oxadiazoles afforded dihydropyrroles in good to excellent yields through an intramolecular…”
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Functionalization of remote C(sp3)-H bonds enabled by copper-catalyzed coupling of O-acyloximes with terminal alkynes by Li, Zhaodong, Torres-Ochoa, Rubén O., Wang, Qian, Zhu, Jieping

“…Transition metal catalyzed Sonogashira cross-coupling of terminal alkynes with aryl(vinyl) (pseudo)halides has been successfully extended to alkyl halides for…”
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Palladium‐Catalyzed Enantioselective Cacchi Reaction: Asymmetric Synthesis of Axially Chiral 2,3‐Disubstituted Indoles by He, Yu‐Ping, Wu, Hua, Wang, Qian, Zhu, Jieping

“…We report herein the first examples of a palladium‐catalyzed enantioselective Cacchi reaction for the synthesis of indoles bearing a chiral C2‐aryl axis. In…”
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C–C bond activation enabled by dyotropic rearrangement of Pd(iv) species by Cao, Jian, Wu, Hua, Wang, Qian, Zhu, Jieping

“…The weak carbon–metal bond combined with the kinetic inertness of the carbon–carbon bond renders metal-catalysed C–C bond activation to be highly challenging…”
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Chiral Phosphoric Acid-Catalyzed Enantioselective Three-Component Povarov Reaction Using Enecarbamates as Dienophiles: Highly Diastereo- and Enantioselective Synthesis of Substituted 4-Aminotetrahydroquinolines by Dagousset, Guillaume, Zhu, Jieping, Masson, Géraldine

“…A chiral phosphoric acid (5)-catalyzed three-component Povarov reaction of aldehydes 2, anilines 3, and enecarbamates 4 afforded…”
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Enantioselective Synthesis of (+)-Peganumine A by Piemontesi, Cyril, Wang, Qian, Zhu, Jieping

“…A gram-scale enantioselective total synthesis of (+)-peganumine A was accomplished in 7 steps from commercially available 6-methoxytryptamine. Key steps…”
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Palladium-Catalyzed Through-Space C(sp3)H and C(sp2)H Bond Activation by 1,4-Palladium Migration: Efficient Synthesis of [3,4]-Fused Oxindoles by Piou, Tiffany, Bunescu, Ala, Wang, Qian, Neuville, Luc, Zhu, Jieping

“…Palladium two step: Linear anilides were converted into the title compounds in good to excellent yields through a palladium‐catalyzed domino…”
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Enantioselective Total Syntheses of Leuconolam–Leuconoxine–Mersicarpine Group Monoterpene Indole Alkaloids by Xu, Zhengren, Wang, Qian, Zhu, Jieping

“…A unified strategy allowing enantioselective total syntheses of (−)-mersicarpine, (−)-scholarisine G, (+)-melodinine E, (−)-leuconoxine, and (−)-leuconolam…”
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Total Synthesis of (±)-Strictamine by Ren, Weiwu, Wang, Qian, Zhu, Jieping

“…The total synthesis of strictamine has been achieved in nine steps from a known enol triflate. Characteristic features of our approach included: a) creation of…”
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Recent Developments in the Isonitrile-Based Multicomponent Synthesis of Heterocycles by Zhu, Jieping

“…Although the synthesis of β‐lactams by means of tethered Ugi reactions has been known since the early 1960s, the 1995 report from Ugi’s group could be regarded…”
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Aqueous Titanium Trichloride Promoted Reductive Cyclization of o-Nitrostyrenes to Indoles: Development and Application to the Synthesis of Rizatriptan and Aspidospermidine by Tong, Shuo, Xu, Zhengren, Mamboury, Mathias, Wang, Qian, Zhu, Jieping

“…Treatment of o‐nitrostyrenes with aqueous TiCl3 solution at room temperature afforded indoles through a formal reductive C(sp2)–H amination process. A range of…”
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