Search Results - "Zhu, Jiankun"

Next generation of tumor-activating type I IFN enhances anti-tumor immune responses to overcome therapy resistance by Cao, Xuezhi, Liang, Yong, Hu, Zhenxiang, Li, Huiyu, Yang, Jiaming, Hsu, Eric J., Zhu, Jiankun, Zhou, Jin, Fu, Yang-Xin

“…Type I interferon is promising in treating different kinds of tumors, but has been limited by its toxicity, lack of tumor targeting, and very short half-life…”
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Toll-Like Receptor Signaling Pathways-Therapeutic Opportunities by Zhu, Jiankun, Mohan, Chandra

“…Toll-like receptors (TLRs) are transmembrane proteins acting mainly as sensors of microbial components. Triggering TLRs results in increased expression of…”
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Tumor-conditional IL-15 pro-cytokine reactivates anti-tumor immunity with limited toxicity by Guo, Jingya, Liang, Yong, Xue, Diyuan, Shen, Jiao, Cai, Yueqi, Zhu, Jiankun, Fu, Yang-Xin, Peng, Hua

“…IL-15 is a promising cytokine to expand NK and CD8 +  T cells for cancer immunotherapy, but its application is limited by dose-limiting, on-target off-tumor…”
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DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity by Lu, Changzheng, Guan, Junhong, Lu, Steve, Jin, Qihuang, Rousseau, Benoit, Lu, Tianshi, Stephens, Dennis, Zhang, Hongyi, Zhu, Jiankun, Yang, Mingming, Ren, Zhenhua, Liang, Yong, Liu, Zhida, Han, Chuanhui, Liu, Longchao, Cao, Xuezhi, Zhang, Anli, Qiao, Jian, Batten, Kimberly, Chen, Mingyi, Castrillon, Diego H., Wang, Tao, Li, Bo, Diaz, Luis A., Li, Guo-Min, Fu, Yang-Xin

“…Increased neoantigens in hypermutated cancers with DNA mismatch repair deficiency (dMMR) are proposed as the major contributor to the high objective response…”
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Development and validation of a TRIM27-based nomogram for predicting metachronous liver metastasis and prognosis in postoperative colorectal cancer patients by Zhu, Jiankun, Zhi, Shilin, Zeng, Jintao, Zhou, Shengning, Ji, Yong, Han, Fanghai

“…Colorectal cancer ranks among the most prevalent malignancies globally. Accurate prediction of metachronous liver metastasis is crucial for optimizing…”
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Curcumin Attenuates Both Acute and Chronic Immune Nephritis by Wu, Tianfu, Marakkath, Bindiya, Ye, Yujin, Khobahy, Elhaum, Yan, Mei, Hutcheson, Jack, Zhu, Jiankun, Zhou, Xinjin, Mohan, Chandra

“…Curcumin is known to have immunomodulatory potential in addition to anti-oxidant, anti-inflammatory and anti-carcinogenic effects. The aim of the present study…”
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Plasmon-induced transparency effect for ultracompact on-chip devices by Niu, Xinxiang, Hu, Xiaoyong, Yan, Qiuchen, Zhu, Jiankun, Cheng, Haotian, Huang, Yifan, Lu, Cuicui, Fu, Yulan, Gong, Qihuang

“…On-chip plasmon-induced transparency (PIT) possessing the unique properties of controlling light propagation states is a promising way to on-chip ultrafast…”
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Efficacy and Safety of Once-Weekly Dulaglutide in Elderly Chinese Patients with Type 2 Diabetes: A Post Hoc Analysis of AWARD-CHN Studies by Kuang, Jian, Zhu, Jiankun, Liu, Siying, Li, Quanmin

“…Introduction This analysis evaluated the efficacy and safety of dulaglutide in Chinese patients with type 2 diabetes (T2D) aged ≥ 60 and < 60 years. Methods…”
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Efficient Management and Scheduling of Massive Remote Sensing Image Datasets by Zhu, Jiankun, Zhang, Zhen, Zhao, Fei, Su, Haoran, Gu, Zhengnan, Wang, Leilei

“…The rapid development of remote sensing image sensor technology has led to exponential increases in available image data. The real-time scheduling of…”
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Prevention of Murine Lupus Nephritis by Targeting Multiple Signaling Axes and Oxidative Stress Using a Synthetic Triterpenoid by Wu, Tianfu, Ye, Yujin, Min, So‐Youn, Zhu, Jiankun, Khobahy, Elhaum, Zhou, Jason, Yan, Mei, Hemachandran, Sriram, Pathak, Simanta, Zhou, Xin J., Andreeff, Michael, Mohan, Chandra

“…Objective Current treatment options for lupus are far from optimal. Previously, we reported that phosphatidylinositol 3‐kinase/Akt/mammalian target of…”
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Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus by Jacob, Chaim O, Zhu, Jiankun, Armstrong, Don L, Yan, Mei, Han, Jie, Zhou, Xin J, Thomas, James A, Reiff, Andreas, Myones, Barry L, Ojwang, Joshua O, Kaufman, Kenneth M, Klein-Gitelman, Marisa, McCurdy, Deborah, Wagner-Weiner, Linda, Silverman, Earl, Ziegler, Julie, Kelly, Jennifer A, Merrill, Joan T, Harley, John B, Ramsey-Goldman, Rosalind, Vila, Luis M, Bae, Sang-Cheol, Vyse, Timothy J, Gilkeson, Gary S, Gaffney, Patrick M, Moser, Kathy L, Langefeld, Carl D, Zidovetzki, Raphael, Mohan, Chandra

“…A combined forward and reverse genetic approach was undertaken to test the candidacy of IRAK1 (interleukin-1 receptor associated kinase-1) as an X…”
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Adverse effects of simulated hyper- and hypo-phosphatemia on endothelial cell function and viability by Peng, Ai, Wu, Tianfu, Zeng, Caihong, Rakheja, Dinesh, Zhu, Jiankun, Ye, Ting, Hutcheson, Jack, Vaziri, Nosratola D, Liu, Zhihong, Mohan, Chandra, Zhou, Xin J

“…Dysregulation of phosphate homeostasis as occurs in chronic kidney disease is associated with cardiovascular complications. It has been suggested that both…”
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A Pragmatic Study of Basal and Mid-Mixture Insulins as Starter Insulins in Chinese Patients With Type 2 Diabetes: Observations From Long-Term, Real-World Experience by Zeng, Tianshu, Yuan, Huijuan, Ren, Jiangong, Li, Yuanyuan, Hou, Jianing, Du, Liying, Zhu, Jiankun, Chen, Lulu, Ji, Linong

“…Introduction According to Chinese guidelines, basal insulin (BI) or premixed insulins are recommended insulin starters following the failure of oral…”
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Effects of milling methods on the dielectric and the mechanical properties of hot-pressed sintered MoSi2/Al2O3 composites by Huang, Zhibin, Zhou, Wancheng, Tang, Xiufeng, Zhu, Jiankun

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Magnetic resonance neuroimaging promotes the preservation of pelvic autonomic nerves in laparoscopic total mesorectal excision: a comparative study by Zhong, Guangyu, Yang, Bin, Zhong, Jinglian, Zhong, Yingkui, Zhi, Shilin, Shen, Jun, Zhou, Shengning, Tan, Jia'nan, Huang, Jing, Zhu, Jiankun, Wang, Dongye, Han, Fanghai

“…How to preserve pelvic autonomic nerves system (PANS) in total mesorectal excision (TME) is still a technical challenge for gastrointestinal surgeons, and…”
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Peritoneal catheter implantation elicits IL-10-producing immune-suppressor macrophages through a MyD88-dependent pathway by Min, So-Youn, Fu, Yuyang, Hutcheson, Jack, Wu, Tianfu, Khobahy, Elhaum, Zhu, Jiankun, Vanarsa, Kamala, Du, Yong, Park, Min-Jung, Park, Hyun-Sil, Saxena, Ramesh, Kim, Ho-Youn, Mohan, Chandra

“…Abstract Catheters are implanted into the peritoneal cavity during the process of peritoneal dialysis. Though these catheters may be effective and beneficial,…”
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Strain distribution pattern of immune nephritis—a follow-up study by Xie, Chun, Rahman, Ziaur S. M., Xie, Shangkui, Zhu, Jiankun, Du, Yong, Qin, Xiangmei, Zhou, Hui, Zhou, Xin J., Mohan, Chandra

“…Previous studies have indicated that the NZW, DBA/1, 129/sv and BUB strains are particularly sensitive to experimental anti-glomerular basement membrane…”
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Logical thinking in pattern differentiation of traditional Chinese medicine by Zhou, Jing, Zhu, Jiankun, Chen, Meijuan, Jiang, Miao, Zhang, Zongming, Zhan, Zhen, Zhang, Xu

“…To discuss the application of logic to pattern differentiation for treatment in Traditional Chinese Medicine (TCM). Comparing logic reasoning of syllogism with…”
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The Lupus-Susceptibility Locus, Sle3, Mediates Enhanced Resistance to Bacterial Infections by Mehrad, Borna, Park, Stacy J, Akangire, Gangaram, Standiford, Theodore J, Wu, Tianfu, Zhu, Jiankun, Mohan, Chandra

“…The genetic predisposition to many autoimmune diseases is inherited as a polygenic trait. It is conceivable that some of the causative alleles in these…”
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Abstract Tu148: cGAS-STING pathway promotes granulopoiesis and neutrophil differentiation in acute ischemia by Zhu, Jiankun, Parra, pablo, Luo, Xiang, Cao, Dian

“…Abstract only Contemporary evidence supports neutrophils' complex roles beyond being the simple and powerful destruction tools in MI. However, our…”
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