Search Results - "Zhu, Heng"
-
1
Transcription factors as readers and effectors of DNA methylation
Published in Nature reviews. Genetics (01-09-2016)“…Key Points Epigenetic profiling has been extensively undertaken in different systems, including development and disease. However, functional characterization…”
Get full text
Journal Article -
2
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases
Published in Nature communications (17-06-2021)“…Fibrotic skin disease represents a major global healthcare burden, characterized by fibroblast hyperproliferation and excessive accumulation of extracellular…”
Get full text
Journal Article -
3
Why Do Countries Respond Differently to COVID-19? A Comparative Study of Sweden, China, France, and Japan
Published in American review of public administration (01-08-2020)“…Nonpharmaceutical interventions (NPIs) are important public health tools to fight against COVID-19. Governments around the world have instituted a variety of…”
Get full text
Journal Article -
4
Economic Impacts of the COVID−19 Lockdown in a Remittance‐Dependent Region
Published in American journal of agricultural economics (01-03-2021)“…The economic impacts of COVID‐19 lockdowns on poor and vulnerable households living in rural areas of developing countries are not well understood due to a…”
Get full text
Journal Article -
5
EnhancerAtlas: a resource for enhancer annotation and analysis in 105 human cell/tissue types
Published in Bioinformatics (Oxford, England) (01-12-2016)“…Multiple high-throughput approaches have recently been developed and allowed the discovery of enhancers on a genome scale in a single experiment. However, the…”
Get full text
Journal Article -
6
Self‐Assembled Wavy Optical Microfiber for Stretchable Wearable Sensor
Published in Advanced optical materials (01-06-2021)“…Smart wearable devices have made remarkable success in medical‐grade human vital signal monitoring and have promoted the realization of precision medicine and…”
Get full text
Journal Article -
7
Ground fissure development regularity and formation mechanism of shallow buried coal seam mining with Karst landform in Jiaozi coal mine: a case study
Published in Journal of mountain science (01-10-2023)“…A comprehensive study was undertaken at Jiaozi coal mine to investigate the development regularity of ground fissures in shallow buried coal seam mining with…”
Get full text
Journal Article -
8
Protein Array-based Approaches for Biomarker Discovery in Cancer
Published in Genomics, proteomics & bioinformatics (01-04-2017)“…Biomarkers are deemed to be potential tools in early diagnosis, therapeutic monitoring, and prognosis evaluation for cancer, with simplicity as well as…”
Get full text
Journal Article -
9
Therapeutic potential of tLyp-1-EV-shCTCF in inhibiting liver cancer stem cell self-renewal and immune escape via SALL3 modulation in hepatocellular carcinoma
Published in Translational oncology (01-11-2024)“…•Sparse SALL3 expression in HCC foretells undesirable patient outcomes.•Boosting SALL3 impedes DNMT3A-facilitated mtDNA methylation and glycolytic…”
Get full text
Journal Article -
10
Preparation of Flame-Retardant Rigid Polyurethane Foams by Combining Modified Melamine–Formaldehyde Resin and Phosphorus Flame Retardants
Published in ACS omega (05-05-2020)“…In this work, ethylene glycol-modified melamine–formaldehyde resin (EMF) was synthesized from ethylene glycol, paraformaldehyde, and melamine, and then rigid…”
Get full text
Journal Article -
11
PARP inhibitors in pancreatic cancer: molecular mechanisms and clinical applications
Published in Molecular cancer (02-03-2020)“…Pancreatic cancer is a highly lethal disease with a poor prognosis, and existing therapies offer only limited effectiveness. Mutation gene sequencing has shown…”
Get full text
Journal Article -
12
Integrating unsupervised language model with triplet neural networks for protein gene ontology prediction
Published in PLoS computational biology (01-12-2022)“…Accurate identification of protein function is critical to elucidate life mechanisms and design new drugs. We proposed a novel deep-learning method, ATGO, to…”
Get full text
Journal Article -
13
Preparation and fire behavior of rigid polyurethane foams synthesized from modified urea-melamine-formaldehyde resins
Published in RSC advances (01-01-2018)“…In this study, a series of ethylene glycol modified urea-melamine-formaldehyde resins (EUMFs) were synthesized from urea, melamine, paraformaldehyde and…”
Get full text
Journal Article -
14
Quercetin inhibits growth of hepatocellular carcinoma by apoptosis induction in part via autophagy stimulation in mice
Published in The Journal of nutritional biochemistry (01-07-2019)“…Quercetin (QCT) has been shown to have anticancer activities associated with apoptosis and autophagy induction. However, whether autophagy is functionally…”
Get full text
Journal Article -
15
Lithium‐Ion Batteries Participating in Frequency Regulation through Low‐Destructive Bidirectional Pulsed Current Operation
Published in Advanced energy materials (01-07-2023)“…Lithium‐ion batteries (LIBs) have enormous potential to participate in the frequency regulation (FR) of future high‐penetration renewable energy grids. This…”
Get full text
Journal Article -
16
MiR-543 Promotes Proliferation and Epithelial-Mesenchymal Transition in Prostate Cancer via Targeting RKIP
Published in Cellular physiology and biochemistry (01-01-2017)“…Background/Aims: MicroRNAs (miRNAs, miRs) have emerged as important post-transcriptional regulators in various cancers. miR-543 has been reported to play…”
Get full text
Journal Article -
17
A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone
Published in Nature protocols (01-03-2010)“…Unlike humans, mouse bone marrow-derived mesenchymal stem cells (MSCs) cannot be easily harvested by adherence to plastic owing to the contamination of…”
Get full text
Journal Article -
18
TiGER: a database for tissue-specific gene expression and regulation
Published in BMC bioinformatics (09-06-2008)“…Understanding how genes are expressed and regulated in different tissues is a fundamental and challenging question. However, most of currently available…”
Get full text
Journal Article -
19
Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain
Published in Nature neuroscience (01-02-2014)“…This study maps the DNA methylome profile of adult mouse dentate gyrus neurons at the single-base resolution and finds prevalent methylation of both CpG…”
Get full text
Journal Article -
20
Opposing Roles for the lncRNA Haunt and Its Genomic Locus in Regulating HOXA Gene Activation during Embryonic Stem Cell Differentiation
Published in Cell stem cell (07-05-2015)“…Long noncoding RNAs (lncRNAs) have been implicated in controlling various aspects of embryonic stem cell (ESC) biology, although the functions of specific…”
Get full text
Journal Article