Search Results - "Zhu, Guoqi"

cAMP-PKA cascade: An outdated topic for depression? by Gao, Feng, Yang, Shaojie, Wang, Juan, Zhu, Guoqi

“…Depression is a common neuropsychiatric disorder characterized by persistent depressed mood and causes serious socioeconomic burden worldwide. Hyperactivity of…”
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7,8-Dihydroxyflavone and Neuropsychiatric Disorders: A Translational Perspective from the Mechanism to Drug Development by Yang, Shaojie, Zhu, Guoqi

“…7,8-Dihydroxyflavone (7,8-DHF) is a kind of natural flavonoid with the potential to cross the blood-brain barrier. 7,8-DHF effectively mimics the effect of…”
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Ginsenoside Rg1 Prevents PTSD-Like Behaviors in Mice Through Promoting Synaptic Proteins, Reducing Kir4.1 and TNF-α in the Hippocampus by Zhang, Zhengrong, Song, Zhujin, Shen, Fengming, Xie, Pan, Wang, Juan, Zhu, Ai-song, Zhu, Guoqi

“…Ginsenoside Rg1 is efficient to prevent or treat mental disorders. However, the mechanisms underlying the effects of ginsenoside Rg1 on post-traumatic stress…”
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Synaptic modification by L-theanine, a natural constituent in green tea, rescues the impairment of hippocampal long-term potentiation and memory in AD mice by Zhu, Guoqi, Yang, Sanjuan, Xie, Zhongwen, Wan, Xiaochun

“…Synaptic refinement improves synaptic efficiency, which provides a possibility to improve memory in Alzheimer's disease (AD). In the current study, we aimed to…”
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MPTP‐induced changes in hippocampal synaptic plasticity and memory are prevented by memantine through the BDNF‐TrkB pathway by Zhu, Guoqi, Li, Junyao, He, Ling, Wang, Xuncui, Hong, Xiaoqi

“…Background and Purpose Mild cognitive deficit in early Parkinson's disease (PD) has been widely studied. Here we have examined the effects of memantine in…”
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Different patterns of electrical activity lead to long-term potentiation by activating different intracellular pathways by Zhu, Guoqi, Liu, Yan, Wang, Yubin, Bi, Xiaoning, Baudry, Michel

“…Deciphering and storing information coded in different firing patterns are important properties of neuronal networks, as they allow organisms to respond and…”
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Use of Steaming Process to Improve Biochemical Activity of Polygonatum sibiricum Polysaccharides against D-Galactose-Induced Memory Impairment in Mice by Bian, Zhijuan, Li, Congting, Peng, Daiyin, Wang, Xuncui, Zhu, Guoqi

“…Polysaccharide from Polygonatum sibiricum (PSP) possesses antioxidant, antiaging, and neuroprotective activities. However, whether and how the steaming process…”
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Distribution of lipid levels and prevalence of hyperlipidemia: data from the NHANES 2007–2018 by Li, Zhenhan, Zhu, Guoqi, Chen, Guo, Luo, Mei, Liu, Xuebo, Chen, Zhongpei, Qian, Jun

“…Abstract Background Lipid-lowering therapy is important, and the distribution of lipid levels and the incidence of hyperlipidemia may vary in different…”
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Ginsenoside Rg1 Prevents Cognitive Impairment and Hippocampal Neuronal Apoptosis in Experimental Vascular Dementia Mice by Promoting GPR30 Expression by Shen, Fengming, Wang, Juan, Gao, Feng, Wang, Jingji, Zhu, Guoqi

“…This study is aimed at investigating the potential roles of G protein-coupled estrogen receptor 1 (GPER, also known as GPR30) in the preventive effect of…”
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Involvement of activation of PI3K/Akt pathway in the protective effects of puerarin against MPP+-induced human neuroblastoma SH-SY5Y cell death by Zhu, Guoqi, Wang, Xuncui, Wu, Shengbing, Li, Qinglin

“…► Puerarin prevents against MPP+-induced cell death through PI3K/Akt signal pathway. ► Puerarin-activated PI3K/Akt signal pathway blocks MPP+-induced p53…”
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Astrocytes and Memory: Implications for the Treatment of Memory-related Disorders by Wang, Juan, Cheng, Ping, Qu, Yan, Zhu, Guoqi

“…Memory refers to the imprint accumulated in the brain by life experiences and represents the basis for humans to engage in advanced psychological activities…”
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Neuroprotective Effects of Puerarin on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine induced Parkinson's Disease Model in Mice by Zhu, Guoqi, Wang, Xuncui, Wu, Shengbing, Li, Xiaoxiang, Li, Qinglin

“…Puerarin, an active component of Pueraria montana var. lobata (Willd.) Sanjappa & Pradeep is well‐known for its anti‐oxidative and neuroprotective activities…”
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PKA and Ube3a regulate SK2 channel trafficking to promote synaptic plasticity in hippocampus: Implications for Angelman Syndrome by Sun, Jiandong, Liu, Yan, Zhu, Guoqi, Cato, Caleb, Hao, Xiaoning, Qian, Li, Lin, Weiju, Adhikari, Rachana, Luo, Yun, Baudry, Michel, Bi, Xiaoning

“…The ubiquitin ligase, Ube3a, plays important roles in brain development and functions, since its deficiency results in Angelman Syndrome (AS) while its…”
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Exploring the effects of moxibustion on cognitive function in rats with multiple cerebral infarctions from the perspective of glial vascular unit repairing by Wang, Jingji, Du, Kunrui, Liu, Chang, Chen, Xiaoyu, Ban, Wenming, Zhu, Guoqi, Yang, Jun

“…Objective This study aimed to explore the effect of moxibustion at Governor Vessel (GV) acupoints, including Baihui (GV 20), Shenting (GV 24) and Dazhui (GV…”
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Clinical Efficacy and Mechanistic Insights of Anshen Dingzhi Prescription on Breast Cancer-Related PTSD Through Network Pharmacology and Molecular Docking by Zhang, Hao, Zhu, Yongfu, Zhu, Guoqi, Yang, Shaojie

“…Anshen Dingzhi prescription (ADP) is a classic prescription of traditional Chinese medicine, which has been used in the treatment of neuropsychiatric diseases…”
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A molecular brake controls the magnitude of long-term potentiation by Wang, Yubin, Zhu, Guoqi, Briz, Victor, Hsu, Yu-Tien, Bi, Xiaoning, Baudry, Michel

“…Overexpression of suprachiasmatic nucleus circadian oscillatory protein (SCOP), a negative ERK regulator, blocks long-term memory encoding. Inhibition of…”
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UBE3A Regulates Synaptic Plasticity and Learning and Memory by Controlling SK2 Channel Endocytosis by Sun, Jiandong, Zhu, Guoqi, Liu, Yan, Standley, Steve, Ji, Angela, Tunuguntla, Rashmi, Wang, Yubin, Claus, Chad, Luo, Yun, Baudry, Michel, Bi, Xiaoning

“…Gated solely by activity-induced changes in intracellular calcium, small-conductance potassium channels (SKs) are critical for a variety of functions in the…”
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New Concepts on the Pathophysiology of Acute Coronary Syndrome by Yuan, Deqiang, Chu, Jiapeng, Qian, Jun, Lin, Hao, Zhu, Guoqi, Chen, Fei, Liu, Xuebo

“…Acute coronary syndrome (ACS) is the most severe form of ischemic heart disease. Although it is caused by atherosclerotic plaque thrombosis or…”
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Mechanism of homocysteine-mediated endothelial injury and its consequences for atherosclerosis by Yuan, Deqiang, Chu, Jiapeng, Lin, Hao, Zhu, Guoqi, Qian, Jun, Yu, Yunan, Yao, Tongqing, Ping, Fan, Chen, Fei, Liu, Xuebo

“…Homocysteine (Hcy) is an intermediate amino acid formed during the conversion from methionine to cysteine. When the fasting plasma Hcy level is higher than 15…”
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Single-Cell RNA Sequencing of Peripheral Blood Mononuclear Cells From Acute Myocardial Infarction by Qian, Jun, Gao, Yanhua, Lai, Yan, Ye, Zi, Yao, Yian, Ding, Keke, Tong, Jing, Lin, Hao, Zhu, Guoqi, Yu, Yunan, Ding, Haoran, Yuan, Deqiang, Chu, Jiapeng, Chen, Fei, Liu, Xuebo

“…Acute myocardial infarction (AMI) can occur in patients with atherosclerotic disease, with or without plaque rupture. Previous studies have indicated a set of…”
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