Search Results - "Zhu, Guizhi"

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics by Zhu, Guizhi, Zheng, Jing, Song, Erqun, Donovan, Michael, Zhang, Kejing, Liu, Chen, Tan, Weihong

“…Nanotechnology has allowed the construction of various nanostructures for applications, including biomedicine. However, a simple target-specific, economical,…”
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DNA Nanoflowers for Multiplexed Cellular Imaging and Traceable Targeted Drug Delivery by Hu, Rong, Zhang, Xiaobing, Zhao, Zilong, Zhu, Guizhi, Chen, Tao, Fu, Ting, Tan, Weihong

“…We present a facile approach to make aptamer‐conjugated FRET (fluorescent resonance energy transfer) nanoflowers (NFs) through rolling circle replication for…”
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Noncanonical Self-Assembly of Multifunctional DNA Nanoflowers for Biomedical Applications by Zhu, Guizhi, Hu, Rong, Zhao, Zilong, Chen, Zhuo, Zhang, Xiaobing, Tan, Weihong

“…DNA nanotechnology has been extensively explored to assemble various functional nanostructures for versatile applications. Mediated by Watson–Crick…”
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Fenton-Reaction-Acceleratable Magnetic Nanoparticles for Ferroptosis Therapy of Orthotopic Brain Tumors by Shen, Zheyu, Liu, Ting, Li, Yan, Lau, Joseph, Yang, Zhen, Fan, Wenpei, Zhou, Zijian, Shi, Changrong, Ke, Chaomin, Bregadze, Vladimir I., Mandal, Swadhin K., Liu, Yijing, Li, Zihou, Xue, Ting, Zhu, Guizhi, Munasinghe, Jeeva, Niu, Gang, Wu, Aiguo, Chen, Xiaoyuan

“…Cancer is one of the leading causes of morbidity and mortality in the world, but more cancer therapies are needed to complement existing regimens due to…”
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Intertwining DNA-RNA nanocapsules loaded with tumor neoantigens as synergistic nanovaccines for cancer immunotherapy by Zhu, Guizhi, Mei, Lei, Vishwasrao, Harshad D., Jacobson, Orit, Wang, Zhantong, Liu, Yijing, Yung, Bryant C., Fu, Xiao, Jin, Albert, Niu, Gang, Wang, Qin, Zhang, Fuwu, Shroff, Hari, Chen, Xiaoyuan

“…Nanomedicines that co-deliver DNA, RNA, and peptide therapeutics are highly desirable yet remain underdeveloped for cancer theranostics. Herein, we report…”
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Nanovaccines for cancer immunotherapy by Zhang, Yu, Lin, Shuibin, Wang, Xiang‐Yang, Zhu, Guizhi

“…The past few decades have witnessed the booming field of cancer immunotherapy. Cancer therapeutic vaccines, either alone or in combination with other…”
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Curvature-Dependent Selectivity of CO2 Electrocatalytic Reduction on Cobalt Porphyrin Nanotubes by Zhu, Guizhi, Li, Yawei, Zhu, Haiyan, Su, Haibin, Chan, Siew Hwa, Sun, Qiang

“…The selective electrocatalytic conversion of CO2 into useful products is a major challenge in facilitating a closed carbon cycle. Here, on the basis of…”
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Building a Multifunctional Aptamer-Based DNA Nanoassembly for Targeted Cancer Therapy by Wu, Cuichen, Han, Da, Chen, Tao, Peng, Lu, Zhu, Guizhi, You, Mingxu, Qiu, Liping, Sefah, Kwame, Zhang, Xiaobing, Tan, Weihong

“…The ability to self-assemble one-dimensional DNA building blocks into two- and three-dimensional nanostructures via DNA/RNA nanotechnology has led to broad…”
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Transformative Nanomedicine of an Amphiphilic Camptothecin Prodrug for Long Circulation and High Tumor Uptake in Cancer Therapy by Zhang, Fuwu, Zhu, Guizhi, Jacobson, Orit, Liu, Yi, Chen, Kai, Yu, Guocan, Ni, Qianqian, Fan, Jing, Yang, Zhen, Xu, Frederick, Fu, Xiao, Wang, Zhe, Ma, Ying, Niu, Gang, Zhao, Xiaobin, Chen, Xiaoyuan

“…We report a camptothecin (CPT) prodrug that was well formulated in solution and rapidly transformed into long-circulating nanocomplexes in vivo for highly…”
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Preparation and biomedical applications of programmable and multifunctional DNA nanoflowers by Lv, Yifan, Hu, Rong, Zhu, Guizhi, Zhang, Xiaobing, Mei, Lei, Liu, Qiaoling, Qiu, Liping, Wu, Cuichen, Tan, Weihong

“…This protocol describes how to prepare multifunctional DNA nanoflowers. Rolling-circle amplification of a designed template containing drug binding, cell…”
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Automated Modular Synthesis of Aptamer–Drug Conjugates for Targeted Drug Delivery by Wang, RuoWen, Zhu, Guizhi, Mei, Lei, Xie, Yan, Ma, Haibin, Ye, Mao, Qing, Feng-Ling, Tan, Weihong

“…Aptamer–drug conjugates (ApDCs) are promising targeted drug delivery systems for reducing toxicity while increasing the efficacy of chemotherapy. However,…”
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In vitro selection with artificial expanded genetic information systems by Sefah, Kwame, Yang, Zunyi, Bradley, Kevin M., Hoshika, Shuichi, Jiménez, Elizabeth, Zhang, Liqin, Zhu, Guizhi, Shanker, Savita, Yu, Fahong, Turek, Diane, Tan, Weihong, Benner, Steven A.

“…Artificially expanded genetic information systems (AEGISs) are unnatural forms of DNA that increase the number of independently replicating nucleotide building…”
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Double‐Layered Plasmonic–Magnetic Vesicles by Self‐Assembly of Janus Amphiphilic Gold–Iron(II,III) Oxide Nanoparticles by Song, Jibin, Wu, Binghui, Zhou, Zijian, Zhu, Guizhi, Liu, Yijing, Yang, Zhen, Lin, Lisen, Yu, Guocan, Zhang, Fuwu, Zhang, Guofeng, Duan, Hongwei, Stucky, Galen D., Chen, Xiaoyuan

“…Janus nanoparticles (JNPs) offer unique features, including the precisely controlled distribution of compositions, surface charges, dipole moments, modular and…”
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Albumin/vaccine nanocomplexes that assemble in vivo for combination cancer immunotherapy by Zhu, Guizhi, Lynn, Geoffrey M., Jacobson, Orit, Chen, Kai, Liu, Yi, Zhang, Huimin, Ma, Ying, Zhang, Fuwu, Tian, Rui, Ni, Qianqian, Cheng, Siyuan, Wang, Zhantong, Lu, Nan, Yung, Bryant C., Wang, Zhe, Lang, Lixin, Fu, Xiao, Jin, Albert, Weiss, Ido D., Vishwasrao, Harshad, Niu, Gang, Shroff, Hari, Klinman, Dennis M., Seder, Robert A., Chen, Xiaoyuan

“…Subunit vaccines have been investigated in over 1000 clinical trials of cancer immunotherapy, but have shown limited efficacy. Nanovaccines may improve…”
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Responsive DNA-Based Hydrogels and Their Applications by Xiong, Xiangling, Wu, Cuichen, Zhou, Cuisong, Zhu, Guizhi, Chen, Zhuo, Tan, Weihong

“…The term hydrogel describes a type of soft and wet material formed by cross‐linked hydrophilic polymers. The distinct feature of hydrogels is their ability to…”
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Self-assembled multifunctional DNA nanoflowers for the circumvention of multidrug resistance in targeted anticancer drug delivery by Mei, Lei, Zhu, Guizhi, Qiu, Liping, Wu, Cuichen, Chen, Huapei, Liang, Hao, Cansiz, Sena, Lv, Yifan, Zhang, Xiaobing, Tan, Weihong

“…Cancer chemotherapy has been limited by its side effects and multidrug resistance （MDR）, the latter of which is partially caused by drug efflux from cancer…”
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Responsive Multivesicular Polymeric Nanovaccines that Codeliver STING Agonists and Neoantigens for Combination Tumor Immunotherapy by Su, Ting, Cheng, Furong, Qi, Jialong, Zhang, Yu, Zhou, Shurong, Mei, Lei, Fu, Shiwei, Zhang, Fuwu, Lin, Shuibin, Zhu, Guizhi

“…Immune checkpoint blockade (ICB) has significantly advanced cancer immunotherapy, yet its patient response rates are generally low. Vaccines, including…”
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Combinatorial Screening of DNA Aptamers for Molecular Imaging of HER2 in Cancer by Zhu, Guizhi, Zhang, Huimin, Jacobson, Orit, Wang, Zhantong, Chen, Haojun, Yang, Xiangyu, Niu, Gang, Chen, Xiaoyuan

“…HER2, a cell membrane protein overexpressed in many types of cancers, is correlated with poor diagnosis, suboptimal treatment outcome, and low survival rate…”
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Engineering a Cell-Surface Aptamer Circuit for Targeted and Amplified Photodynamic Cancer Therapy by Han, Da, Zhu, Guizhi, Wu, Cuichen, Zhu, Zhi, Chen, Tao, Zhang, Xiaobing, Tan, Weihong

“…Photodynamic therapy is one of the most promising and noninvasive methods for clinical treatment of different malignant diseases. Here, we present a novel…”
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Near-Infrared Light-Responsive Core–Shell Nanogels for Targeted Drug Delivery by Kang, Huaizhi, Trondoli, Anna Carolina, Zhu, Guizhi, Chen, Yan, Chang, Ya-Jen, Liu, Haipeng, Huang, Yu-Fen, Zhang, Xiaoling, Tan, Weihong

“…A near-infrared light-responsive drug delivery platform based on Au–Ag nanorods (Au–Ag NRs) coated with DNA cross-linked polymeric shells was constructed. DNA…”
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