Search Results - "Zhu, Gaohui"
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Genetic causes of growth hormone insensitivity beyond GHR
Published in Reviews in endocrine & metabolic disorders (01-03-2021)“…Growth hormone insensitivity (GHI) syndrome, first described in 1966, is classically associated with monogenic defects in the GH receptor ( GHR ) gene which…”
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2
Skeletal overgrowth in a pre-pubescent child treated with pan-FGFR inhibitor
Published in Heliyon (15-06-2024)“…Fibroblast growth factors and their receptors (FGFR) have major roles in both human growth and oncogenesis. In adults, therapeutic FGFR inhibitors have been…”
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3
Noggin resistance contributes to the potent osteogenic capability of BMP9 in mesenchymal stem cells
Published in Journal of orthopaedic research (01-11-2013)“…Mesenchymal stem cells (MSCs) are multipotent progenitors and can differentiate into osteogenic, chondrogenic, and adipogenic lineages. Bone morphogenetic…”
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4
Effects of Aquatic Exercise and Floor Curling on Balance Ability and Lower Limb Muscle Strength in Children with Intellectual Disabilities: A Pilot Study in China
Published in Children (Basel) (01-01-2024)“…Children with intellectual disabilities often face challenges in balance ability and lower limb muscle strength, which negatively impact their daily lives and…”
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Four novel mutations identification in 17 beta-hydroxysteroid dehydrogenase-3 deficiency and our clinical experience: possible benefits of early treatment
Published in Frontiers in endocrinology (Lausanne) (15-02-2024)“…Individuals with 17-beta-hydroxysteroid dehydrogenase type 3 (17β-HSD3) deficiency face a multitude of challenges, primarily concerning genital appearance,…”
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6
Growth hormone synergizes with BMP9 in osteogenic differentiation by activating the JAK/STAT/IGF1 pathway in murine multilineage cells
Published in Journal of bone and mineral research (01-07-2012)“…Growth hormone (GH) is usually released by somatotrophs in the anterior pituitary in response to the GH‐releasing hormone and plays an important role in…”
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BMP-9 induced osteogenic differentiation of mesenchymal stem cells: molecular mechanism and therapeutic potential
Published in Current gene therapy (01-06-2011)“…Promoting osteogenic differentiation and efficacious bone regeneration have the potential to revolutionize the treatment of orthopaedic and musculoskeletal…”
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Defective Osteogenic Differentiation in the Development of Osteosarcoma
Published in Sarcoma (2011)“…Osteosarcoma (OS) is associated with poor prognosis due to its high incidence of metastasis and chemoresistance. It often arises in areas of rapid bone growth…”
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9
Mesenchymal Progenitor Cells and Their Orthopedic Applications : Forging a Path towards Clinical Trials
Published in Stem cells international (01-01-2010)“…Mesenchymal progenitor cells (MPCs) are nonhematopoietic multipotent cells capable of differentiating into mesenchymal and nonmesenchymal lineages. While they…”
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10
Effects of aquatic exercise intervention on executive function and brain-derived neurotrophic factor of children with autism spectrum disorder
Published in Research in developmental disabilities (01-07-2024)“…Limited knowledge exists regarding the effectiveness of aquatic exercise intervention for improving executive function (EF) in children with autism spectrum…”
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11
Three cases of 3β-hydroxysteroid dehydrogenase deficiency: Clinical analysis
Published in Advances in clinical and experimental medicine : official organ Wroclaw Medical University (01-03-2021)“…3β-HSD deficiency is a rare type of congenital adrenal hyperplasia (CAH), which is caused by HSD3B2 gene mutations. In order to improve the understanding and…”
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12
Analysis of bone mass and its relationship with body composition in school-aged children and adolescents based on stage of puberty and site specificity: A retrospective case-control study
Published in Medicine (Baltimore) (01-02-2019)“…The aim of this study was to better understand the relationship of bone mass with body composition based on different stages of puberty and to illuminate the…”
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13
Immunopeptidome mining reveals a novel ERS-induced target in T1D
Published in Cellular & molecular immunology (01-06-2024)“…Autoreactive CD8 + T cells play a key role in type 1 diabetes (T1D), but the antigen spectrum that activates autoreactive CD8 + T cells remains unclear…”
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14
Reference centiles for evaluating total body fat development and fat distribution by dual-energy x-ray absorptiometry among children and adolescents aged 3–18 years
Published in Clinical nutrition (Edinburgh, Scotland) (01-03-2021)“…The rise in the prevalence of childhood obesity has increased the demand for accurately evaluating body fatness in pediatric population. The aim of this study…”
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Regional Adipose Compartments Confer Different Cardiometabolic Risk in Children and Adolescents: The China Child and Adolescent Cardiovascular Health Study
Published in Mayo Clinic proceedings (01-10-2019)“…Objective: To investigate the associations of fat mass in specific regions with cardiometabolic risk factors in Chinese children and adolescents.Patients and…”
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En masse organoid phenotyping informs metabolic-associated genetic susceptibility to NASH
Published in Cell (27-10-2022)“…Genotype-phenotype associations for common diseases are often compounded by pleiotropy and metabolic state. Here, we devised a pooled human organoid-panel of…”
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Cross‐talk between EGF and BMP9 signalling pathways regulates the osteogenic differentiation of mesenchymal stem cells
Published in Journal of cellular and molecular medicine (01-09-2013)“…Mesenchymal stem cells (MSCs) are multipotent progenitors, which give rise to several lineages, including bone, cartilage and fat. Epidermal growth factor…”
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18
Regional Adipose Compartments Confer Different Cardiometabolic Risk in Children and Adolescents
Published in Mayo Clinic proceedings (01-10-2019)“…To investigate the associations of fat mass in specific regions with cardiometabolic risk factors in Chinese children and adolescents. This cross-sectional…”
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19
Interaction between the gut microbiota and colonic enteroendocrine cells regulates host metabolism
Published in Nature metabolism (01-06-2024)“…Nutrient handling is an essential function of the gastrointestinal tract. Hormonal responses of small intestinal enteroendocrine cells (EECs) have been…”
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Anti-diabetic compounds from the seeds of Psoralea corylifolia
Published in Fitoterapia (01-11-2019)“…A new aurone named (2Z)-2-[(4′-hydroxyphenyl) methylene]-6-hydroxy-7-prenyl-3(2H)-benzofurane (1), two new flavonoids named…”
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