Search Results - "Zhu, Chune"
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PLGA microsphere-based composite hydrogel for dual delivery of ciprofloxacin and ginsenoside Rh2 to treat Staphylococcus aureus-induced skin infections
Published in Drug delivery (01-01-2020)“…When antibiotic-resistant pathogenic bacteria pose a high threat to human health, bacterial multidrug efflux pumps become major contributors to the high-level…”
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2
microRNA Temporal-Specific Expression Profiles Reveal longissimus dorsi Muscle Development in Tianzhu White Yak
Published in International journal of molecular sciences (21-09-2024)“…As a class of regulatory factors, microRNAs (miRNAs) play an important role in regulating normal muscle development and fat deposition. Muscle and adipose…”
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3
TPGS/hyaluronic acid dual-functionalized PLGA nanoparticles delivered through dissolving microneedles for markedly improved chemo-photothermal combined therapy of superficial tumor
Published in Acta pharmaceutica Sinica. B (01-10-2021)“…Nanoparticles (NPs) have shown potential in cancer therapy, while a single administration conferring a satisfactory outcome is still unavailable. To address…”
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4
Mutations in the FOXO3 Gene and Their Effects on Meat Traits in Gannan Yaks
Published in International journal of molecular sciences (06-02-2024)“…The gene, a prominent member of the FOXO family, has been identified as a potential quantitative trait locus for muscle atrophy and lipid metabolism in…”
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5
Variation in Acetyl-CoA Carboxylase Beta Gene and Its Effect on Carcass and Meat Traits in Gannan Yaks
Published in International journal of molecular sciences (01-10-2023)“…Acetyl-CoA carboxylase beta (ACACB) is a functional candidate gene that impacts fat deposition. In the present study, we sequenced exon 37–intron 37, exon…”
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6
Improving the stability and transdermal permeability of phycocyanin loaded cubosomes
Published in Frontiers in nanotechnology (11-04-2024)“…Instability and low transdermal permeability of protein antioxidants are major obstacles to resist oxidative stress in transdermal drug delivery system. To…”
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Influence of Polymers on the Physical and Chemical Stability of Spray-dried Amorphous Solid Dispersion: Dipyridamole Degradation Induced by Enteric Polymers
Published in AAPS PharmSciTech (01-08-2018)“…Amorphous solid dispersions (ASDs) are inherently unstable because of high internal energy. Evaluating physical and chemical stability during the process and…”
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Development of composite PLGA microspheres containing exenatide-encapsulated lecithin nanoparticles for sustained drug release
Published in Asian journal of pharmceutical sciences (01-05-2020)“…•PLGA microspheres based on exenatide encapsulated in nanoparticles were developed.•Ex-NPs-PLGA-Ms was prepared by modified S/O/W method with a low initial…”
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9
Variation in the HSL Gene and Its Association with Carcass and Meat Quality Traits in Yak
Published in Animals (Basel) (01-12-2023)“…Hormone-sensitive lipase ( ) is involved in the breakdown of triacylglycerols in adipose tissue, which influences muscle tenderness and juiciness by affecting…”
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Anhydrous reverse micelle nanoparticles: new strategy to overcome sedimentation instability of peptide-containing pressurized metered-dose inhalers
Published in Drug delivery (01-01-2017)“…The objective of this study was to develop a novel anhydrous reverse micelle nanoparticles (ARM-NPs) system to overcome the sedimentation instability of…”
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11
Data on the drug release profiles and powder characteristics of the ethyl cellulose based microparticles prepared by the ultra-fine particle processing system
Published in Data in brief (01-04-2020)“…Ethyl cellulose (EC) based microparticles (MPs) could provide sustained release for Huperzine A. The drug release mechanism of MPs was exploited to achieve an…”
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Anhydrous reverse micelle lecithin nanoparticles/PLGA composite microspheres for long-term protein delivery with reduced initial burst
Published in Colloids and surfaces, B, Biointerfaces (01-03-2018)“…[Display omitted] •Reverse lecithin micelle/PLGA microspheres were developed by S/O/W technique.•Properties of microspheres prepared by S/O/W and W/O/W methods…”
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13
Enhanced stability of an emulsion enriched in unsaturated fatty acids by dual natural antioxidants fortified in both the aqueous and oil phases
Published in Food hydrocolloids (01-09-2018)“…Emulsions containing unsaturated fatty acids (UFAs) have potential in the treatment of clinical malnutrition. However, the stability of UFAs is a major problem…”
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14
Silk fibroin nanoparticles for enhanced bio-macromolecule delivery to the retina
Published in Pharmaceutical development and technology (28-05-2019)“…The aim of this study was to investigate intravitreal injection of silk fibroin nanoparticles (SFNs) encapsulating bio-macromolecules, achieving enhanced drug…”
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Novel strategy for immunomodulation: Dissolving microneedle array encapsulating thymopentin fabricated by modified two-step molding technology
Published in European journal of pharmaceutics and biopharmaceutics (01-01-2018)“…[Display omitted] •TP5-DMNA was developed using a two-step molding technology for immunomodulation.•BSA was used as co-material to fabricate TP5-DMNA for…”
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16
Long-stranded non-coding RNAs temporal-specific expression profiles reveal longissimus dorsi muscle development and intramuscular fat deposition in Tianzhu white yak
Published in Journal of animal science (03-01-2023)“…Abstract The process of muscle development and intramuscular fat (IMF) deposition is quite complex and controlled by both mRNAs and ncRNAs. Long-stranded…”
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The practical self-targeted oncolytic adenoviral nanosphere based on immuno-obstruction method via polyprotein surface precipitation technique enhances transfection efficiency for virotherapy
Published in Biochemical and biophysical research communications (15-01-2019)“…Recent developments in tumour treatment had focused on virotherapies that were currently revolutionising new innovated treatment pathways. This study focused…”
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In vitro evaluation of drug delivery behavior for inhalable amorphous nanoparticle formulations in a human lung epithelial cell model
Published in International journal of pharmaceutics (01-03-2021)“…[Display omitted] Respiratory tract infections caused by multidrug-resistant (MDR) Gram-negative bacteria such as Pseudomonas aeruginosa are serious burdens to…”
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Formation Mechanism, In vitro and In vivo Evaluation of Dimpled Exenatide Loaded PLGA Microparticles Prepared by Ultra-Fine Particle Processing System
Published in AAPS PharmSciTech (01-02-2019)“…Spherical poly (D, L-lactic-co-glycolic acid) microparticles (PLGA-MPs) have long been investigated in order to achieve sustained delivery of…”
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20
Mutations in the IFOXO3/I Gene and Their Effects on Meat Traits in Gannan Yaks
Published in International journal of molecular sciences (01-02-2024)“…The FOXO3 gene, a prominent member of the FOXO family, has been identified as a potential quantitative trait locus for muscle atrophy and lipid metabolism in…”
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