Search Results - "Zhou, Yile"
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Parent-child Interactions in Numeracy Activities: Parental Scaffolding, Mathematical Talk, and Game Format
Published in Early childhood research quarterly (01-01-2022)“…•Examined the game format effect on parent-preschooler interactions•Compared technology-based game format with traditional board game format•Focused on…”
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2
SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints
Published in Leukemia (01-11-2019)“…SETD2 , an epigenetic tumor suppressor, is frequently mutated in MLL-rearranged (MLLr) leukemia and relapsed acute leukemia (AL). To clarify the impact of…”
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The regulatory effect of microRNA-21a-3p on the promotion of telocyte angiogenesis mediated by PI3K (p110α)/AKT/mTOR in LPS induced mice ARDS
Published in Journal of translational medicine (26-12-2019)“…Telocytes (TCs) are newly identified interstitial cells that participate in tissue protection and repair. The present study investigated the mechanisms…”
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4
Lys694Arg polymorphism leads to blunted responses to LPS by interfering TLR4 with recruitment of MyD88
Published in Innate immunity (London, England) (01-08-2021)“…TLR4 polymorphisms such as Asp299Gly and Thr399Ile related to Gram-negative sepsis have been reported to result in significantly blunted responsiveness to LPS…”
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5
Tregs dysfunction aggravates postoperative cognitive impairment in aged mice
Published in Journal of neuroinflammation (17-03-2023)“…Enhanced neuroinflammation is an important mechanism underlying perioperative neurocognitive disorders. Regulatory T cells (Tregs) play a crucial role in…”
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Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC
Published in Haematologica (Roma) (01-01-2020)“…Homoharringtonine, a plant alkaloid, has been reported to suppress protein synthesis and has been approved by the US Food and Drug Administration for the…”
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Enhancement of oral bioavailability and anti-Parkinsonian efficacy of resveratrol through a nanocrystal formulation
Published in Asian journal of pharmceutical sciences (01-07-2020)“…Resveratrol (RES), a non-flavonoid polyphenol extracted from a wide variety of plants, exhibits neuroprotective activities against Parkinson's disease (PD)…”
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Metformin Protects Against Diabetes-Induced Cognitive Dysfunction by Inhibiting Mitochondrial Fission Protein DRP1
Published in Frontiers in pharmacology (22-03-2022)“…Diabetes is an independent risk factor for dementia. Mitochondrial dysfunction is a critical player in diabetes and diabetic complications. The present study…”
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Telocytes reduce oxidative stress by downregulating DUOX2 expression in inflamed lungs of mice
Published in Acta biochimica et biophysica Sinica (25-04-2022)“…Telocytes (TCs), a novel type of interstitial cells, have been found to participate in tissue protection and repair. In this study, we investigated the…”
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10
Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation
Published in Haematologica (Roma) (01-07-2018)“…( ), encoding a histone methyltransferase, is associated with many hematopoietic diseases when mutated. By generating a novel exon 6 conditional knockout mouse…”
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BIG1 controls macrophage pro-inflammatory responses through ARF3-mediated PI(4,5)P2 synthesis
Published in Cell death & disease (15-05-2020)“…Sepsis is caused by a dysregulated host inflammatory response to serious infections resulting in life-threatening organ dysfunction. The high morbidity and…”
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Influence of gene modification in biological behaviors and responses of mouse lung telocytes to inflammation
Published in Journal of translational medicine (15-05-2019)“…Telocytes play key roles in maintenance of organ/tissue function and prevention of organ injury. However, there are great challenges to investigate telocytes…”
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Inactivated vaccine dosage and serum IgG levels correlate with persistent COVID-19 infections in hematologic malignancy patients during the Omicron Surge in China
Published in BMC infectious diseases (11-10-2024)“…The essence of this scholarly work was to carefully outline the key factors intensifying the virulence and protracted contagion of COVID-19, particularly among…”
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The high NRF2 expression confers chemotherapy resistance partly through up-regulated DUSP1 in myelodysplastic syndromes
Published in Haematologica (Roma) (01-03-2019)“…Although cytarabine has been widely considered as one of the chemotherapy drugs for high-risk myelodysplastic syndromes (MDS), the overall response rate is…”
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High PARP-1 expression predicts poor survival in acute myeloid leukemia and PARP-1 inhibitor and SAHA-bendamustine hybrid inhibitor combination treatment synergistically enhances anti-tumor effects
Published in EBioMedicine (01-12-2018)“…PARP-1 plays a critical role in DNA damage repair and contributes to progression of cancer. To explore the role of PARP-1 in acute myeloid leukemia (AML), we…”
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Co-mutation landscape and its prognostic impact on newly diagnosed adult patients with NPM1-mutated de novo acute myeloid leukemia
Published in Blood cancer journal (New York) (22-07-2024)Get full text
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Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes
Published in Cancer discovery (01-11-2018)“…Myelodysplastic syndromes (MDS) are heterogeneous hematopoietic disorders that are incurable with conventional therapy. Their incidence is increasing with…”
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Repressing HIF-1α-induced HDAC9 contributes to the synergistic effect of venetoclax and MENIN inhibitor in KMT2Ar AML
Published in Biomarker research (05-12-2023)“…Abstract KMT2A -rearranged acute myeloid leukemia ( KMT2A r-AML) is an aggressive subtype of AML with poor response and prognosis. KMT2A r-AML has been…”
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Clinical characteristics and prognostic values of 1p32.3 deletion detected through fluorescence in situ hybridization in patients with newly diagnosed multiple myeloma: a single-center study in China
Published in Frontiers of medicine (01-06-2020)“…This study aimed to investigate the prevalence, clinical characteristics, and prognostic impact of 1p32.3 deletion in patients with newly diagnosed multiple…”
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HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis
Published in Haematologica (Roma) (01-11-2017)“…Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome characterized by overwhelming immune activation. A steroid and chemotherapy-based…”
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