Search Results - "Zhou, Yabo"
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Mucus production stimulated by IFN-AhR signaling triggers hypoxia of COVID-19
Published in Cell research (01-12-2020)“…Silent hypoxia has emerged as a unique feature of coronavirus disease 2019 (COVID-19). In this study, we show that mucins are accumulated in the…”
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Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype
Published in Nature communications (28-02-2018)“…Resetting tumor-associated macrophages (TAMs) is a promising strategy to ameliorate the immunosuppressive tumor microenvironment and improve innate and…”
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IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor
Published in Nature immunology (01-03-2021)“…CD8 + T cell exhaustion dampens antitumor immunity. Although several transcription factors have been identified that regulate T cell exhaustion, the molecular…”
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Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program
Published in Cancer research (Chicago, Ill.) (15-07-2018)“…Dormancy is recognized as a critical biological event for tumorigenic cells surviving in an extremely harsh environment. Understanding the molecular process of…”
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Gasdermin E mediates resistance of pancreatic adenocarcinoma to enzymatic digestion through a YBX1–mucin pathway
Published in Nature cell biology (01-03-2022)“…Pancreatic ductal adenocarcinoma (PDAC) originates from normal pancreatic ducts where digestive juice is regularly produced. It remains unclear how PDAC can…”
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Numerical and theoretical analysis of multi-pillar instability under elastic beams
Published in Geomatics, natural hazards and risk (31-12-2024)“…AbstractWith the increase of mining scale and depth, the cascading pillar failure (CPF) disaster has gradually become one of the core technical challenges for…”
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SARS-CoV-2 treatment effects induced by ACE2-expressing microparticles are explained by the oxidized cholesterol-increased endosomal pH of alveolar macrophages
Published in Cellular & molecular immunology (01-02-2022)“…Exploring the cross-talk between the immune system and advanced biomaterials to treat SARS-CoV-2 infection is a promising strategy. Here, we show that…”
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Visualization of perforin/gasdermin/complement-formed pores in real cell membranes using atomic force microscopy
Published in Cellular & molecular immunology (01-06-2019)“…Different types of pores ubiquitously form in cell membranes, leading to various types of cell death that profoundly influence the fate of inflammation and the…”
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Cell softness renders cytotoxic T lymphocytes and T leukemic cells resistant to perforin-mediated killing
Published in Nature communications (15-02-2024)“…Mechanical force contributes to perforin pore formation at immune synapses, thus facilitating the cytotoxic T lymphocytes (CTL)-mediated killing of tumor cells…”
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Metformin Use and Survival in Patients with Advanced Extrahepatic Cholangiocarcinoma: A Single-Center Cohort Study in Fuyang, China
Published in Gastroenterology research and practice (2021)“…Aims. Metformin is an oral antidiabetic agent that has been widely prescribed for the treatment of type II diabetes. In recent years, anticancer properties of…”
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Remediation of grassland subsidence and reduction of land occupation with tailings backfill technology: a case study of lead-zinc mine in Inner Mongolia, China
Published in Frontiers in environmental science (11-05-2023)“…The mining industry provides essential mineral resources for human society’s development. However, this industry generates a large quantity of waste material…”
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ACE2 expression is regulated by AhR in SARS-CoV-2-infected macaques
Published in Cellular & molecular immunology (01-05-2021)Get full text
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Subtyping of microsatellite stability colorectal cancer reveals guanylate binding protein 2 (GBP2) as a potential immunotherapeutic target
Published in Journal for immunotherapy of cancer (01-04-2022)“…BackgroundsProficient-mismatch-repair or microsatellite stability (pMMR/MSS) colorectal cancer (CRC) has limited efficacy for immune checkpoint blockade (ICB)…”
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Escaping alveolar macrophage endosomal retention explains massive expansion of SARS-CoV-2 delta variant
Published in Signal transduction and targeted therapy (17-12-2021)Get full text
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Cell softness regulates tumorigenicity and stemness of cancer cells
Published in The EMBO journal (15-01-2021)Get full text
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YAP Inactivation by Soft Mechanotransduction Relieves MAFG for Tumor Cell Dedifferentiation
Published in Research (Washington) (22-08-2023)“…Solid tumor cells live in a highly dynamic mechanical microenvironment. How the extracellular-matrix-generated mechanotransduction regulates tumor cell…”
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Comparative Analysis of Theoretical, Observational, and Modeled Deformation of Ground Subsidence: The Case of the Alhada Pb-Zn Mine
Published in Minerals (Basel) (01-08-2022)“…In this study, the probability integral method, Synthetic Aperture Radar Interferometry (InSAR), and the Okada dislocation model were collaboratively used to…”
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Publisher Correction: Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype
Published in Nature communications (01-05-2018)“…In the originally published version of this Article, images in Fig. 5n were inadvertently replaced with duplicates of images in Fig. 5o during the production…”
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Research on the evolution of the wheel polygon based on the iterative model of long-term wear on both sides of the wheelset
Published in Vehicle system dynamics (03-10-2023)“…The high-frequency excitation generated by the wheel polygon seriously affects the safety of the train. In order to explore the evolution mechanism of wheel…”
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