Search Results - "Zhou, Xiuxia"

Targeting the ubiquitin pathway for cancer treatment by Liu, Jia, Shaik, Shavali, Dai, Xiangpeng, Wu, Qiong, Zhou, Xiuxia, Wang, Zhiwei, Wei, Wenyi

“…Proteasome-mediated degradation is a common mechanism by which cells renew their intracellular proteins and maintain protein homeostasis. In this process, the…”
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Antitumor activity of curcumin is involved in down-regulation of YAP/TAZ expression in pancreatic cancer cells by Zhou, Xiuxia, Su, Jingna, Feng, Shaoyan, Wang, Lixia, Yin, Xuyuan, Yan, Jingzhe, Wang, Zhiwei

“…Pancreatic cancer (PC) is one of the most aggressive human malignancies worldwide and is the fourth leading cause of cancer-related deaths. Curcumin…”
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Regulation of RIP3 by the transcription factor Sp1 and the epigenetic regulator UHRF1 modulates cancer cell necroptosis by Yang, Chengkui, Li, Jun, Yu, Lu, Zhang, Zili, Xu, Feng, Jiang, Lang, Zhou, Xiuxia, He, Sudan

“…Receptor-interacting kinase-3 (RIP3) is a key regulator of necroptosis. It has been shown that the expression of RIP3 is silenced in most cancer cells and…”
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Dysfunctional ErbB2, an EGF receptor family member, hinders repair of airway epithelial cells from asthmatic patients by Inoue, Hideki, Hattori, Takeshi, Zhou, Xiuxia, Etling, Emily B., Modena, Brian D., Trudeau, John B., Holguin, Fernando, Wenzel, Sally E.

“…Genetic and genomic data increasingly point to the airway epithelium as critical to asthma pathogenesis. Epithelial growth factor (EGF) family members play a…”
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Compartmentalized mitochondrial ferroptosis converges with optineurin-mediated mitophagy to impact airway epithelial cell phenotypes and asthma outcomes by Yamada, Kazuhiro, St. Croix, Claudette, Stolz, Donna B., Tyurina, Yulia Y., Tyurin, Vladimir A., Bradley, Laura R., Kapralov, Alexander A., Deng, Yanhan, Zhou, Xiuxia, Wei, Qi, Liao, Bo, Fukuda, Nobuhiko, Sullivan, Mara, Trudeau, John, Ray, Anuradha, Kagan, Valerian E., Zhao, Jinming, Wenzel, Sally E.

“…A stable mitochondrial pool is crucial for healthy cell function and survival. Altered redox biology can adversely affect mitochondria through induction of a…”
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DDX5 facilitates HIV-1 replication as a cellular co-factor of Rev by Zhou, Xiuxia, Luo, Juan, Mills, Lisa, Wu, Shuangxin, Pan, Ting, Geng, Guannan, Zhang, Jim, Luo, Haihua, Liu, Chao, Zhang, Hui

“…HIV-1 Rev plays an important role in the late phase of HIV-1 replication, which facilitates export of unspliced viral mRNAs from the nucleus to cytoplasm in…”
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The functions of F-box proteins in regulating the epithelial to mesenchymal transition by Su, Jingna, Yin, Xuyuan, Zhou, Xiuxia, Wei, Wenyi, Wang, Zhiwei

“…Epithelial to mesenchymal transition (EMT) has been unraveled to regulate the tumor invasion and metastasis processes. In this review, in order to better…”
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MAPK regulation of IL-4/IL-13 receptors contributes to the synergistic increase in CCL11/eotaxin-1 in response to TGF-β1 and IL-13 in human airway fibroblasts by Zhou, Xiuxia, Hu, Haizhen, Balzar, Silvana, Trudeau, John B, Wenzel, Sally E

“…CCL11/eotaxin-1 is a potent eosinophilic CC chemokine expressed by primary human fibroblasts. The combination of TGF-β1 and IL-13 synergistically increases…”
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BRD4 PROTAC degrader MZ1 exhibits anti-B-cell acute lymphoblastic leukemia effects via targeting CCND3 by Ma, Li, Wang, Jianwei, Yang, Yang, Lu, Jun, Ling, Jing, Chu, Xinran, Zhang, Zimu, Tao, Yanfang, Li, Xiaolu, Tian, Yuanyuan, Li, Zhiheng, Zhang, Yongping, Sang, Xu, Lu, Lihui, Wan, Xiaomei, Zhang, Kunlong, Chen, Yanling, Yu, Juanjuan, Zhuo, Ran, Wu, Shuiyan, Pan, Jian, Zhou, Xiuxia, Hu, Yixin, Hu, Shaoyan

“…INTRODUCTIONB-cell acute lymphoblastic leukemia (B-ALL) is the most prevalent malignant tumor affecting children. While the majority of B-ALL patients (90%)…”
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Machine learning implicates the IL-18 signaling axis in severe asthma by Camiolo, Matthew J, Zhou, Xiuxia, Wei, Qi, Trejo Bittar, Humberto E, Kaminski, Naftali, Ray, Anuradha, Wenzel, Sally E

“…Asthma is a common disease with profoundly variable natural history and patient morbidity. Heterogeneity has long been appreciated, and much work has focused…”
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Genomic differences distinguish the myofibroblast phenotype of distal lung fibroblasts from airway fibroblasts by Zhou, Xiuxia, Wu, Wei, Hu, Haizhen, Milosevic, Jadranka, Konishi, Kazuhisa, Kaminski, Naftali, Wenzel, Sally E

“…Primary human distal lung/parenchymal fibroblasts (DLFs) exhibit a different phenotype from airway fibroblasts (AFs), including the expression of high levels…”
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Regional Fibroblast Heterogeneity in the Lung: Implications for Remodeling by Kotaru, Chakradhar, Schoonover, Kathryn J, Trudeau, John B, Huynh, Mai-Lan, Zhou, XiuXia, Hu, Haizhen, Wenzel, Sally E

“…Excessive deposition of extracellular matrix occurs in proximal airways of individuals with asthma, but fibrosis in distal lung has not been observed. Whether…”
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Mechanisms of tissue inhibitor of metalloproteinase 1 augmentation by IL-13 on TGF-β1–stimulated primary human fibroblasts by Zhou, Xiuxia, PhD, Hu, Haizhen, BS, Huynh, Mai-Lan N., MD, Kotaru, Chakradhar, MD, Balzar, Silvana, MD, Trudeau, John B., BA, Wenzel, Sally E., MD

“…Background TGF-β induces expression of tissue inhibitor of metalloproteinase 1 (TIMP-1), a potent inhibitor of matrix metalloproteinases that controls…”
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Targeting Cdc20 as a novel cancer therapeutic strategy by Wang, Lixia, Zhang, Jinfang, Wan, Lixin, Zhou, Xiuxia, Wang, Zhiwei, Wei, Wenyi

“…The Anaphase Promoting Complex (APC, also called APC/C) regulates cell cycle progression by forming two closely related, but functionally distinct E3 ubiquitin…”
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Smart Nanomedicine to Enable Crossing Blood–Brain Barrier Delivery of Checkpoint Blockade Antibody for Immunotherapy of Glioma by Wang, Hairong, Chao, Yu, Zhao, He, Zhou, Xiuxia, Zhang, Fuyong, Zhang, Zheng, Li, Zhiheng, Pan, Jian, Wang, Jian, Chen, Qian, Liu, Zhuang

“…Immune checkpoint blockade (ICB) therapy has shown tremendous promises in the treatment of various types of tumors. However, ICB therapy with antibodies…”
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Syntheses, characterization, and luminescence of two lanthanide complexes [Ln2(acetate)6(H2O)4]·4H2O (Ln=Tb(1), Sm(2)) by YU, Qiongyan, ZHOU, Xiuxia, LIU, Maosheng, CHEN, Jianqiao, ZHOU, Zhengyuan, YIN, Xia, CAI, Yuepeng

“…Two dinuclear compounds [Ln2(acetate)6(H2O)4]*4H2O (Ln=Tb(1), Sm(2)) were obtained by the hydrothermal reaction of Ln2O3 with malonic acid at 150 deg C. Both…”
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Heat transfer modeling and analysis of air-layer integrated radiant cooling unit by Zhang, Nan, Liang, Yuying, Wu, Huijun, Xu, Xinhua, Du, Ke, Shao, Zhenhua, Zhou, Xiuxia, Huang, Gongsheng

“…[Display omitted] •Heat transfer model of air-layer integrated radiant cooling unit was developed.•The developed two-flux model was validated to be reliable…”
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Multi-signaling pathway activation by pH responsive manganese particles for enhanced vaccination by Lv, Xinjing, Huang, Jie, Min, Jie, Wang, Hairong, Xu, Yunyun, Zhang, Zimu, Zhou, Xiuxia, Wang, Jian, Liu, Zhuang, Zhao, He

“…As metal ions play important roles in the process of immunomodulation, immunotherapy based on metal ions has attracted tremendous interests in recent years…”
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Furin Enzyme and pH Synergistically Triggered Aggregation of Gold Nanoparticles for Activated Photoacoustic Imaging and Photothermal Therapy of Tumors by Cheng, Xiaju, Zhou, Xiuxia, Xu, Jingwei, Sun, Rui, Xia, Huawei, Ding, Jianan, Chin, Y. Eugene, Chai, Zhifang, Shi, Haibin, Gao, Mingyuan

“…Specific and effective accumulation of nanoparticles within tumors is highly crucial for precise cancer diagnosis and treatment. Therefore, spatiotemporally…”
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The effects of curcumin on proliferation, apoptosis, invasion, and NEDD4 expression in pancreatic cancer by Su, Jingna, Zhou, Xiuxia, Yin, Xuyuan, Wang, Lixia, Zhao, Zhe, Hou, Yingying, Zheng, Nana, Xia, Jun, Wang, Zhiwei

“…[Display omitted] Pancreatic cancer (PC) is one of the most fatal cancers worldwide. The incidence and death rates are still increasing for PC. Curcumin is the…”
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