Search Results - "Zhou, Xikun"
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Tumor-Associated Macrophages: Recent Insights and Therapies
Published in Frontiers in oncology (25-02-2020)“…Macrophages, which have functions of engulfing and digesting foreign substances, can clear away harmful matter, including cellular debris and tumor cells…”
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Lung microbiome: new insights into the pathogenesis of respiratory diseases
Published in Signal transduction and targeted therapy (17-01-2024)“…The lungs were long thought to be sterile until technical advances uncovered the presence of the lung microbial community. The microbiome of healthy lungs is…”
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3
Exo-circRNAs: a new paradigm for anticancer therapy
Published in Molecular cancer (30-03-2019)“…CircRNAs, as new members of long noncoding RNAs, have been the focus of recent investigation. CircRNAs feature a closed continuous loop structure without 5'-3'…”
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The Role of Circular RNAs in Immune-Related Diseases
Published in Frontiers in immunology (02-04-2020)“…Circular RNAs (circRNAs) are a novel class of RNAs with a covalently closed loop structure without a 3' polyadenylation [poly-(A)] tail or a 5' cap. They used…”
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5
Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin inflammation
Published in Autophagy (01-02-2021)“…The precise mechanism through which macroautophagy/autophagy affects psoriasis is poorly understood. Here, we found that keratinocyte (KC) autophagy, which was…”
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Extracellular Vesicles: Recent Insights Into the Interaction Between Host and Pathogenic Bacteria
Published in Frontiers in immunology (25-05-2022)“…Extracellular vesicles (EVs) are nanosized lipid particles released by virtually every living cell. EVs carry bioactive molecules, shuttle from cells to cells…”
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7
An integrated multi-omics analysis of identifies distinct molecular characteristics in pulmonary infections of Pseudomonas aeruginosa
Published in PLoS pathogens (29-08-2023)“…Pseudomonas aeruginosa ( P . aeruginosa ) can cause severe acute infections, including pneumonia and sepsis, and cause chronic infections, commonly in patients…”
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Extrachromosomal circular DNA (eccDNA): an emerging star in cancer
Published in Biomarker research (26-07-2022)“…Abstract Extrachromosomal circular DNA (eccDNA) is defined as a type of circular DNA that exists widely in nature and is independent of chromosomes. EccDNA has…”
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Intricate confrontation: Research progress and application potential of TRIM family proteins in tumor immune escape
Published in Journal of advanced research (01-12-2023)“…Tripartite motif (TRIM) family proteins have more than 80 members and are widely found in various eukaryotic cells. Most TRIM family proteins participate in…”
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IL-37 ameliorates the inflammatory process in psoriasis by suppressing proinflammatory cytokine production
Published in The Journal of immunology (1950) (15-02-2014)“…IL-37 is a potent inhibitor of innate immunity by shifting the cytokine equilibrium away from excessive inflammation. Psoriasis is thought to be initiated by…”
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Biofilm formation: mechanistic insights and therapeutic targets
Published in Molecular biomedicine (15-12-2023)“…Biofilms are complex multicellular communities formed by bacteria, and their extracellular polymeric substances are observed as surface-attached or…”
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Evolution of lasR mutants in polymorphic Pseudomonas aeruginosa populations facilitates chronic infection of the lung
Published in Nature communications (25-09-2023)“…Chronic infection with the bacterial pathogen Pseudomonas aeruginosa often leads to coexistence of heterogeneous populations carrying diverse mutations. In…”
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Atg7 enhances host defense against infection via downregulation of superoxide but upregulation of nitric oxide
Published in The Journal of immunology (1950) (01-02-2015)“…Pseudomonas aeruginosa is an opportunistic bacterium that can cause serious infection in immunocompromised individuals. Although autophagy may augment immune…”
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14
MicroRNA-302b negatively regulates IL-1β production in response to MSU crystals by targeting IRAK4 and EphA2
Published in Arthritis research & therapy (26-02-2018)“…Interleukin-1β (IL-1β) is a pivotal proinflammatory cytokine that is strongly associated with the inflammation of gout. However, the underlying mechanism…”
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15
Effect of Tree Quantity and Distribution on the Electric Field under Transmission Lines
Published in Applied sciences (01-09-2024)“…The electric field of transmission lines has serious negative impacts on residents’ production and life with the expansion of high voltage engineering. In…”
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DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia
Published in The Journal of immunology (1950) (01-04-2017)“…Oxygen is supplied as a supportive treatment for patients suffering from acute respiratory distress syndrome. Unfortunately, high oxygen concentration…”
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Applications of nanomaterials as treatments and diagnostic biosensors in microbial infections
Published in MedComm - Biomaterials and applications (01-12-2023)“…Microbial infection is a major medical problem that seriously threatens public health. The abuse of antibiotics that help evolve the emergence of new…”
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Identification of a BRAF/PA28γ/MEK1 signaling axis and its role in epithelial-mesenchymal transition in oral submucous fibrosis
Published in Cell death & disease (12-08-2022)“…Oral submucous fibrosis (OSF) is a chronic and insidious oral potentially malignant disorder associated with a 4–17% risk of oral squamous cell carcinoma…”
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Repurposing Dimetridazole and Ribavirin to disarm Pseudomonas aeruginosa virulence by targeting the quorum sensing system
Published in Frontiers in microbiology (15-08-2022)“…Pseudomonas aeruginosa relies on its complex cellular regulatory network to produce a series of virulence factors and to cause various acute and chronic…”
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Biodegradable thermosensitive hydrogel for SAHA and DDP delivery: therapeutic effects on oral squamous cell carcinoma xenografts
Published in PloS one (18-04-2012)“…OSCC is one of the most common malignancies and numerous clinical agents currently applied in combinative chemotherapy. Here we reported a novel therapeutic…”
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