Search Results - "Zhou, Xiao Xiong"
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Red meat consumption and risk for dyslipidaemia and inflammation: A systematic review and meta-analysis
Published in Frontiers in cardiovascular medicine (30-09-2022)“…Aim The study (PROSPERO: CRD42021240905) aims to reveal the relationships among red meat, serum lipids and inflammatory biomarkers. Methods and results PubMed,…”
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Discovery of 4′-azido-2′-deoxy-2′-C-methyl cytidine and prodrugs thereof: A potent inhibitor of Hepatitis C virus replication
Published in Bioorganic & medicinal chemistry letters (01-05-2012)“…4′-Azido-2′-deoxy-2′-methylcytidine (14) is a potent nucleoside inhibitor of the HCV NS5B RNA-dependent RNA polymerase, displaying an EC50 value of 1.2μM and…”
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Nucleoside analogs as anti-HBV agents
Published in Current topics in medicinal chemistry (01-05-2006)“…Chronic hepatitis B virus (HBV) infection affects about 400 million people worldwide. The development of nucleoside analogs that inhibit HBV polymerase…”
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The Design, Synthesis, and Antiviral Activity of Monofluoro and Difluoro Analogues of 4′-Azidocytidine against Hepatitis C Virus Replication: The Discovery of 4′-Azido-2′-deoxy-2′-fluorocytidine and 4′-Azido-2′-dideoxy-2′,2′-difluorocytidine
Published in Journal of medicinal chemistry (14-05-2009)“…The discovery of 4′-azidocytidine (3) (R1479) ( J. Biol. Chem. 2006, 281, 3793 ; Bioorg. Med. Chem. Lett. 2007, 17, 2570 ) as a potent inhibitor of RNA…”
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The Design, Synthesis, and Antiviral Activity of 4′-Azidocytidine Analogues against Hepatitis C Virus Replication: The Discovery of 4′-Azidoarabinocytidine
Published in Journal of medicinal chemistry (08-01-2009)“…4′-Azidocytidine 3 (R1479) has been previously discovered as a potent and selective inhibitor of HCV replication targeting the RNA-dependent RNA polymerase of…”
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β-Branched acyclic nucleoside analogues as inhibitors of Plasmodium falciparum dUTPase
Published in Bioorganic & medicinal chemistry (01-04-2011)“…We report a series of β-branched acyclic tritylated deoxyuridine analogues as inhibitors of Plasmodium falciparum deoxyuridine-5′-triphosphate…”
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Outside blockholders and corporate performance: Evidence from China IPO firms
Published in 2008 International Conference on Management Science and Engineering 15th Annual Conference Proceedings (01-09-2008)“…Based on Chinese firms initially publicly offering (IPO) in 2000 and 2001, we investigate the relationship between outside blockholderspsila ownership and…”
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Relationships between tunneling parameters of TBM and rock chip characteristics based on image analysis
Published in Yan tu li xue (01-04-2024)Get full text
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Validation of Microdialysis Sampling for Oral Availability Studies by Means of a New Ganciclovir Prodrug
Published in Pharmacology & toxicology (01-06-2002)“…: Microdialysis sampling was validated for oral availability studies using ganciclovir (9‐(1, 3‐dihydroxy‐2‐propoxymethyl) guanine) and a ganciclovir prodrug…”
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Anti-HBV Activities of Novel 2′,3′-C-substituted beta- l-nucleoside Analogues
Published in Antiviral research (01-05-2011)Get full text
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Apoptosis of human pancreatic cancer cells induced by Triptolide
Published in World journal of gastroenterology : WJG (14-03-2008)“…AIM: To investigate apoptosis in human pancreatic cancer cells induced by Triptolide (TL), and the relationship between this apoptosis and expression of…”
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Modified 5′-Trityl Nucleosides as Inhibitors of Plasmodium falciparum dUTPase
Published in ChemMedChem (07-02-2011)“…2′‐Deoxyuridine triphosphate nucleotidohydrolase (dUTPase) is a potential drug target for the treatment of malaria. We previously reported the discovery of…”
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Phenethylthiazolethiourea (PETT) Compounds, a New Class of HIV-1 Reverse Transcriptase Inhibitors. 1. Synthesis and Basic Structure-Activity Relationship Studies of PETT Analogs
Published in Journal of medicinal chemistry (01-12-1995)“…A novel series of potent specific HIV-1 inhibitory compounds is described. The lead compound in the series, N-(2-phenethyl)-N'-(2-thiazolyl)thiourea (1),…”
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Cover Picture: Synthesis and Evaluation of Indatraline-Based Inhibitors for Trypanothione Reductase / Design, Synthesis and Biological Evaluation of Novel Inhibitors of Trypanosoma brucei Pteridine Reductase 1 / Modified 5′-Trityl Nucleosides as Inhibitors of Plasmodium falciparum dUTPase (ChemMedChem 2/2011)
Published in ChemMedChem (07-02-2011)Get full text
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Effect of primary percutaneous coronary intervention on plasma B-type natriuretic peptide in patients with acute myocardial infarction
Published in Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA (01-12-2005)“…To observe the effect of primary percutaneous coronary intervention (PCI) on plasma B-type natriuretc peptide (BNP) in patients with acute myocardial…”
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Predicting heavy metals' adsorption edges and adsorption isotherms on MnO2 with the parameters determined from Langmuir kinetics
Published in Journal of environmental sciences (China) (2015)“…Although surface complexation models have been widely used to describe the adsorption of heavy metals, few studies have verified the feasibility of modeling…”
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Aminoglycoside ototoxicity in three murine strains and effects on NKCC1 of stria vascularis
Published in Chinese medical journal (20-06-2006)“…Background After establishing a murine model of aminoglycoside antibiotic (AmAn) induced ototoxicity, the sensitivity of AmAn induced ototoxicity in three…”
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Pathological Changes in Heroin-induced Spongiform Leukoencephalopathy and Therapeutic Effect of Comprehensive Rehabilitation: A Follow-up Study (Abstract)
Published in Journal of acupuncture and tuina science (2005)“…Objective: To explore the pathological mechanism and effective comprehensive rehabilitation protocol of heroin-induced spongiform leukoencephalopathy (HSLE)…”
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Journal Article