Search Results - "Zhou, Weiyin"

Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study by Shi, Jianxin, Hua, Xing, Zhu, Bin, Ravichandran, Sarangan, Wang, Mingyi, Nguyen, Cu, Brodie, Seth A, Palleschi, Alessandro, Alloisio, Marco, Pariscenti, Gianluca, Jones, Kristine, Zhou, Weiyin, Bouk, Aaron J, Boland, Joseph, Hicks, Belynda, Risch, Adam, Bennett, Hunter, Luke, Brian T, Song, Lei, Duan, Jubao, Liu, Pengyuan, Kohno, Takashi, Chen, Qingrong, Meerzaman, Daoud, Marconett, Crystal, Laird-Offringa, Ite, Mills, Ian, Caporaso, Neil E, Gail, Mitchell H, Pesatori, Angela C, Consonni, Dario, Bertazzi, Pier Alberto, Chanock, Stephen J, Landi, Maria Teresa

“…Lung adenocarcinoma (LUAD) is the most common histologic subtype of lung cancer and has a high risk of distant metastasis at every disease stage. We aimed to…”
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Lack of transgenerational effects of ionizing radiation exposure from the Chernobyl accident by Yeager, Meredith, Machiela, Mitchell J, Kothiyal, Prachi, Dean, Michael, Bodelon, Clara, Suman, Shalabh, Wang, Mingyi, Mirabello, Lisa, Nelson, Chase W, Zhou, Weiyin, Palmer, Cameron, Ballew, Bari, Colli, Leandro M, Freedman, Neal D, Dagnall, Casey, Hutchinson, Amy, Vij, Vibha, Maruvka, Yosi, Hatch, Maureen, Illienko, Iryna, Belayev, Yuri, Nakamura, Nori, Chumak, Vadim, Bakhanova, Elena, Belyi, David, Kryuchkov, Victor, Golovanov, Ivan, Gudzenko, Natalia, Cahoon, Elizabeth K, Albert, Paul, Drozdovitch, Vladimir, Little, Mark P, Mabuchi, Kiyohiko, Stewart, Chip, Getz, Gad, Bazyka, Dimitry, Berrington de Gonzalez, Amy, Chanock, Stephen J

“…Effects of radiation exposure from the Chernobyl nuclear accident remain a topic of interest. We investigated germline de novo mutations (DNMs) in children…”
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Whole genome sequencing of skull-base chordoma reveals genomic alterations associated with recurrence and chordoma-specific survival by Bai, Jiwei, Shi, Jianxin, Li, Chuzhong, Wang, Shuai, Zhang, Tongwu, Hua, Xing, Zhu, Bin, Koka, Hela, Wu, Ho-Hsiang, Song, Lei, Wang, Difei, Wang, Mingyi, Zhou, Weiyin, Ballew, Bari J., Zhu, Bin, Hicks, Belynda, Mirabello, Lisa, Parry, Dilys M., Zhai, Yixuan, Li, Mingxuan, Du, Jiang, Wang, Junmei, Zhang, Shuheng, Liu, Qian, Zhao, Peng, Gui, Songbai, Goldstein, Alisa M., Zhang, Yazhuo, Yang, Xiaohong R.

“…Chordoma is a rare bone tumor with an unknown etiology and high recurrence rate. Here we conduct whole genome sequencing of 80 skull-base chordomas and…”
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Mosaic chromosome Y loss is associated with alterations in blood cell counts in UK Biobank men by Lin, Shu-Hong, Loftfield, Erikka, Sampson, Josh N., Zhou, Weiyin, Yeager, Meredith, Freedman, Neal D., Chanock, Stephen J., Machiela, Mitchell J.

“…Mosaic loss of Y chromosome (mLOY) is the most frequently detected somatic copy number alteration in leukocytes of men. In this study, we investigate blood…”
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Genome-wide association study identifies multiple new loci associated with Ewing sarcoma susceptibility by Machiela, Mitchell J., Grünewald, Thomas G. P., Surdez, Didier, Reynaud, Stephanie, Mirabeau, Olivier, Karlins, Eric, Rubio, Rebeca Alba, Zaidi, Sakina, Grossetete-Lalami, Sandrine, Ballet, Stelly, Lapouble, Eve, Laurence, Valérie, Michon, Jean, Pierron, Gaelle, Kovar, Heinrich, Gaspar, Nathalie, Kontny, Udo, González-Neira, Anna, Picci, Piero, Alonso, Javier, Patino-Garcia, Ana, Corradini, Nadège, Bérard, Perrine Marec, Freedman, Neal D., Rothman, Nathaniel, Dagnall, Casey L., Burdett, Laurie, Jones, Kristine, Manning, Michelle, Wyatt, Kathleen, Zhou, Weiyin, Yeager, Meredith, Cox, David G., Hoover, Robert N., Khan, Javed, Armstrong, Gregory T., Leisenring, Wendy M., Bhatia, Smita, Robison, Leslie L., Kulozik, Andreas E., Kriebel, Jennifer, Meitinger, Thomas, Metzler, Markus, Hartmann, Wolfgang, Strauch, Konstantin, Kirchner, Thomas, Dirksen, Uta, Morton, Lindsay M., Mirabello, Lisa, Tucker, Margaret A., Tirode, Franck, Chanock, Stephen J., Delattre, Olivier

“…Ewing sarcoma (EWS) is a pediatric cancer characterized by the EWSR1 - FLI1 fusion. We performed a genome-wide association study of 733 EWS cases and 1346…”
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Detectable chromosome X mosaicism in males is rarely tolerated in peripheral leukocytes by Zhou, Weiyin, Lin, Shu-Hong, Khan, Sairah M., Yeager, Meredith, Chanock, Stephen J., Machiela, Mitchell J.

“…Age-related male Y and female X chromosome mosaicism is commonly observed in large population-based studies. To investigate the frequency of male X chromosome…”
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Mosaic chromosomal alterations in peripheral blood leukocytes of children in sub-Saharan Africa by Zhou, Weiyin, Fischer, Anja, Ogwang, Martin D., Luo, Wen, Kerchan, Patrick, Reynolds, Steven J., Tenge, Constance N., Were, Pamela A., Kuremu, Robert T., Wekesa, Walter N., Masalu, Nestory, Kawira, Esther, Kinyera, Tobias, Otim, Isaac, Legason, Ismail D., Nabalende, Hadijah, Ayers, Leona W., Bhatia, Kishor, Goedert, James J., Gouveia, Mateus H., Cole, Nathan, Hicks, Belynda, Jones, Kristine, Hummel, Michael, Schlesner, Mathias, Chagaluka, George, Mutalima, Nora, Borgstein, Eric, Liomba, George N., Kamiza, Steve, Mkandawire, Nyengo, Mitambo, Collins, Molyneux, Elizabeth M., Newton, Robert, Glaser, Selina, Kretzmer, Helene, Manning, Michelle, Hutchinson, Amy, Hsing, Ann W., Tettey, Yao, Adjei, Andrew A., Chanock, Stephen J., Siebert, Reiner, Yeager, Meredith, Prokunina-Olsson, Ludmila, Machiela, Mitchell J., Mbulaiteye, Sam M.

“…In high-income countries, mosaic chromosomal alterations in peripheral blood leukocytes are associated with an elevated risk of adverse health outcomes,…”
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Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue by Shi, Jianxin, Marconett, Crystal N., Duan, Jubao, Hyland, Paula L., Li, Peng, Wang, Zhaoming, Wheeler, William, Zhou, Beiyun, Campan, Mihaela, Lee, Diane S., Huang, Jing, Zhou, Weiyin, Triche, Tim, Amundadottir, Laufey, Warner, Andrew, Hutchinson, Amy, Chen, Po-Han, Chung, Brian S. I., Pesatori, Angela C., Consonni, Dario, Bertazzi, Pier Alberto, Bergen, Andrew W., Freedman, Mathew, Siegmund, Kimberly D., Berman, Benjamin P., Borok, Zea, Chatterjee, Nilanjan, Tucker, Margaret A., Caporaso, Neil E., Chanock, Stephen J., Laird-Offringa, Ite A., Landi, Maria Teresa

“…The genetic regulation of the human epigenome is not fully appreciated. Here we describe the effects of genetic variants on the DNA methylome in human lung…”
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Evaluation of alcohol-free mouthwash for studies of the oral microbiome by Yano, Yukiko, Vogtmann, Emily, Shreves, Alaina H, Weinstein, Stephanie J, Black, Amanda, Diaz-Mayoral, Norma, Wan, Yunhu, Zhou, Weiyin, Hua, Xing, Dagnall, Casey L, Hutchinson, Amy, Jones, Kristine, Hicks, Belynda D, Wyatt, Kathleen, Brotzman, Michelle, Gerlanc, Nicole, Huang, Wen-Yi, Albert, Paul S, Wentzensen, Nicolas, Abnet, Christian C

“…Oral bacteria play important roles in human health and disease. Oral samples collected using ethanol-containing mouthwash are widely used for oral microbiome…”
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Genome Analysis of Latin American Cervical Cancer: Frequent Activation of the PIK3CA Pathway by Lou, Hong, Villagran, Guillermo, Boland, Joseph F, Im, Kate M, Polo, Sarita, Zhou, Weiyin, Odey, Ushie, Juárez-Torres, Eligia, Medina-Martínez, Ingrid, Roman-Basaure, Edgar, Mitchell, Jason, Roberson, David, Sawitzke, Julie, Garland, Lisa, Rodríguez-Herrera, Maria, Wells, David, Troyer, Jennifer, Pinto, Francisco Castillo, Bass, Sara, Zhang, Xijun, Castillo, Miriam, Gold, Bert, Morales, Hesler, Yeager, Meredith, Berumen, Jaime, Alvirez, Enrique, Gharzouzi, Eduardo, Dean, Michael

“…Cervical cancer is one of the most common causes of cancer mortality for women living in poverty, causing more than 28,000 deaths annually in Latin America and…”
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Germline-somatic JAK2 interactions are associated with clonal expansion in myelofibrosis by Brown, Derek W., Zhou, Weiyin, Wang, Youjin, Jones, Kristine, Luo, Wen, Dagnall, Casey, Teshome, Kedest, Klein, Alyssa, Zhang, Tongwu, Lin, Shu-Hong, Lee, Olivia W., Khan, Sairah, Vo, Jacqueline B., Hutchinson, Amy, Liu, Jia, Wang, Jiahui, Zhu, Bin, Hicks, Belynda, Martin, Andrew St, Spellman, Stephen R., Wang, Tao, Deeg, H. Joachim, Gupta, Vikas, Lee, Stephanie J., Freedman, Neal D., Yeager, Meredith, Chanock, Stephen J., Savage, Sharon A., Saber, Wael, Gadalla, Shahinaz M., Machiela, Mitchell J.

“…Myelofibrosis is a rare myeloproliferative neoplasm (MPN) with high risk for progression to acute myeloid leukemia. Our integrated genomic analysis of up to…”
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Imaging incorporation of circulating docosahexaenoic acid into the human brain using positron emission tomography by Umhau, John C., Zhou, Weiyin, Carson, Richard E., Rapoport, Stanley I., Polozova, Alla, Demar, James, Hussein, Nahed, Bhattacharjee, Abesh K., Ma, Kaizong, Esposito, Giuseppe, Majchrzak, Sharon, Herscovitch, Peter, Eckelman, William C., Kurdziel, Karen A., Salem, Norman

“…Docosahexaenoic acid (DHA; 22:6n-3) is a critical constituent of the brain, but its metabolism has not been measured in the human brain in vivo. In monkeys,…”
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Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma by Lin, Shu-Hong, Sampson, Joshua N., Grünewald, Thomas G. P., Surdez, Didier, Reynaud, Stephanie, Mirabeau, Olivier, Karlins, Eric, Rubio, Rebeca Alba, Zaidi, Sakina, Grossetête-Lalami, Sandrine, Ballet, Stelly, Lapouble, Eve, Laurence, Valérie, Michon, Jean, Pierron, Gaelle, Kovar, Heinrich, Kontny, Udo, González-Neira, Anna, Alonso, Javier, Patino-Garcia, Ana, Corradini, Nadège, Bérard, Perrine Marec, Miller, Jeremy, Freedman, Neal D., Rothman, Nathaniel, Carter, Brian D., Dagnall, Casey L., Burdett, Laurie, Jones, Kristine, Manning, Michelle, Wyatt, Kathleen, Zhou, Weiyin, Yeager, Meredith, Cox, David G., Hoover, Robert N., Khan, Javed, Armstrong, Gregory T., Leisenring, Wendy M., Bhatia, Smita, Robison, Leslie L., Kulozik, Andreas E., Kriebel, Jennifer, Meitinger, Thomas, Metzler, Markus, Krumbholz, Manuela, Hartmann, Wolfgang, Strauch, Konstantin, Kirchner, Thomas, Dirksen, Uta, Mirabello, Lisa, Tucker, Margaret A., Tirode, Franck, Morton, Lindsay M., Chanock, Stephen J., Delattre, Olivier, Machiela, Mitchell J.

“…Background Ewing sarcoma (EwS) is a rare, aggressive solid tumor of childhood, adolescence and young adulthood associated with pathognomonic EWSR1-ETS fusion…”
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Evolution of multiple cell clones over a 29-year period of a CLL patient by Zhao, Zhikun, Goldin, Lynn, Liu, Shiping, Wu, Liang, Zhou, Weiyin, Lou, Hong, Yu, Qichao, Tsang, Shirley X., Jiang, Miaomiao, Li, Fuqiang, McMaster, MaryLou, Li, Yang, Lin, Xinxin, Wang, Zhifeng, Xu, Liqin, Marti, Gerald, Li, Guibo, Wu, Kui, Yeager, Meredith, Yang, Huanming, Xu, Xun, Chanock, Stephen J., Li, Bo, Hou, Yong, Caporaso, Neil, Dean, Michael

“…Chronic lymphocytic leukaemia (CLL) is a frequent B-cell malignancy, characterized by recurrent somatic chromosome alterations and a low level of point…”
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Genomic profiles and clinical presentation of chordoma by Koka, Hela, Zhou, Weiyin, McMaster, Mary L, Bai, Jiwei, Luo, Wen, Klein, Alyssa, Zhang, Tongwu, Hua, Xing, Li, Xin, Wang, Difei, Xiong, Yujia, Jones, Kristine, Vogt, Aurelie, Hicks, Belynda, Parry, Dilys, Goldstein, Alisa M, Yang, Xiaohong R

“…Chordoma is a rare bone cancer with variable clinical outcomes. Here, we recruited 184 sporadic chordoma patients from the US and Canada and collected their…”
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Prognostic impact of pre-transplant chromosomal aberrations in peripheral blood of patients undergoing unrelated donor hematopoietic cell transplant for acute myeloid leukemia by Wang, Youjin, Zhou, Weiyin, McReynolds, Lisa J., Katki, Hormuzd A., Griffiths, Elizabeth A., Thota, Swapna, Machiela, Mitchell J., Yeager, Meredith, McCarthy, Philip, Pasquini, Marcelo, Wang, Junke, Karaesmen, Ezgi, Rizvi, Abbas, Preus, Leah, Tang, Hancong, Wang, Yiwen, Pooler, Loreall, Sheng, Xin, Haiman, Christopher A., Van Den Berg, David, Spellman, Stephen R., Wang, Tao, Kuxhausen, Michelle, Chanock, Stephen J., Lee, Stephanie J., Hahn, Theresa E., Sucheston-Campbell, Lara E., Gadalla, Shahinaz M.

“…To improve risk stratification and treatment decisions for patients with acute myeloid leukemia (AML) undergoing hematopoietic cell transplantation (HCT). We…”
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Successful use of whole genome amplified DNA from multiple source types for high-density Illumina SNP microarrays by Dagnall, Casey L, Morton, Lindsay M, Hicks, Belynda D, Li, Shengchao, Zhou, Weiyin, Karlins, Eric, Teshome, Kedest, Chowdhury, Salma, Lashley, Kerrie S, Sampson, Joshua N, Robison, Leslie L, Armstrong, Gregory T, Bhatia, Smita, Radloff, Gretchen A, Davies, Stella M, Tucker, Margaret A, Yeager, Meredith, Chanock, Stephen J

“…The recommended genomic DNA input requirements for whole genome single nucleotide polymorphism microarrays can limit the scope of molecular epidemiological…”
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Reply to ‘Mosaic loss of chromosome Y in leukocytes matters’ by Zhou, Weiyin, Machiela, Mitchell J., Freedman, Neal D., Rothman, Nathaniel, Malats, Nuria, Dagnall, Casey, Caporaso, Neil, Teras, Lauren T., Gaudet, Mia M., Gapstur, Susan M., Stevens, Victoria L., Jacobs, Kevin B., Sampson, Joshua, Albanes, Demetrius, Weinstein, Stephanie, Virtamo, Jarmo, Berndt, Sonja, Hoover, Robert N., Black, Amanda, Silverman, Debra, Figueroa, Jonine, Garcia-Closas, Montserrat, Real, Francisco X., Earl, Julie, Marenne, Gaelle, Rodriguez-Santiago, Benjamin, Karagas, Margaret, Johnson, Alison, Schwenn, Molly, Wu, Xifeng, Gu, Jian, Ye, Yuanqing, Hutchinson, Amy, Tucker, Margaret, Perez-Jurado, Luis A., Dean, Michael, Yeager, Meredith, Chanock, Stephen J.

“…[...] it was an observation from our laboratory that first identified the presence of genetic mosaicism in a population sample of 'healthy' individuals7…”
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Alternative Splicing of the G Protein-Coupled Receptor Superfamily in Human Airway Smooth Muscle Diversifies the Complement of Receptors by Einstein, Richard, Jordan, Heather, Zhou, Weiyin, Brenner, Michael, Moses, Esther G., Liggett, Stephen B.

“…G protein-coupled receptors (GPCRs) are the largest signaling family in the genome, serve an expansive array of functions, and are targets for ≈50% of current…”
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XAF1 as a modifier of p53 function and cancer susceptibility by Pinto, Emilia M, Figueiredo, Bonald C, Chen, Wenan, Galvao, Henrique C R, Formiga, Maria Nirvana, Fragoso, Maria Candida B V, Ashton-Prolla, Patricia, Ribeiro, Enilze M S F, Felix, Gabriela, Costa, Tatiana E B, Savage, Sharon A, Yeager, Meredith, Palmero, Edenir I, Volc, Sahlua, Salvador, Hector, Fuster-Soler, Jose Luis, Lavarino, Cinzia, Chantada, Guillermo, Vaur, Dominique, Odone-Filho, Vicente, Brugières, Laurence, Else, Tobias, Stoffel, Elena M, Maxwell, Kara N, Achatz, Maria Isabel, Kowalski, Luis, de Andrade, Kelvin C, Pappo, Alberto, Letouze, Eric, Latronico, Ana Claudia, Mendonca, Berenice B, Almeida, Madson Q, Brondani, Vania B, Bittar, Camila M, Soares, Emerson W S, Mathias, Carolina, Ramos, Cintia R N, Machado, Moara, Zhou, Weiyin, Jones, Kristine, Vogt, Aurelie, Klincha, Payal P, Santiago, Karina M, Komechen, Heloisa, Paraizo, Mariana M, Parise, Ivy Z S, Hamilton, Kayla V, Wang, Jinling, Rampersaud, Evadnie, Clay, Michael R, Murphy, Andrew J, Lalli, Enzo, Nichols, Kim E, Ribeiro, Raul C, Rodriguez-Galindo, Carlos, Korbonits, Marta, Zhang, Jinghui, Thomas, Mark G, Connelly, Jon P, Pruett-Miller, Shondra, Diekmann, Yoan, Neale, Geoffrey, Wu, Gang, Zambetti, Gerard P

“…Cancer risk is highly variable in carriers of the common R337H founder allele, possibly due to the influence of modifier genes. Whole-genome sequencing…”
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