Search Results - "Zhou, Qiyin"

SIRT1 deacetylated and stabilized XRCC1 to promote chemoresistance in lung cancer by Yousafzai, Neelum Aziz, Zhou, Qiyin, Xu, Wenxia, Shi, Qiqi, Xu, Jinye, Feng, Lifeng, Chen, Hui, Shin, Vivian Yvonne, Jin, Hongchuan, Wang, Xian

“…Chemoresistance is one of the most important challenges in the clinical management of lung cancer. SIRT1 is a NAD dependent protein deacetylase and implicated…”
Get full text

β-catenin represses miR455-3p to stimulate m6A modification of HSF1 mRNA and promote its translation in colorectal cancer by Song, Ping, Feng, Lifeng, Li, Jiaqiu, Dai, Dongjun, Zhu, Liyuan, Wang, Chaoqun, Li, Jingyi, Li, Ling, Zhou, Qiyin, Shi, Rongkai, Wang, Xian, Jin, Hongchuan

“…Abstract Background Heat shock transcription factor1 (HSF1) was overexpressed to promote glutaminolysis and activate mTOR in colorectal cancer (CRC). Here, we…”
Get full text

Neddylation regulation of mitochondrial structure and functions by Zhou, Qiyin, Zheng, Yawen, Sun, Yi

“…Mitochondria are the powerhouse of a cell. The structure and function of mitochondria are precisely regulated by multiple signaling pathways. Neddylation, a…”
Get full text

Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3SPOP E3 ligase in cancer cells by Zhou, Qiyin, Lin, Wenyu, Wang, Chaoqun, Sun, Fei, Ju, Siwei, Chen, Qian, Wang, Yi, Chen, Yongxia, Li, Haomin, Wang, Linbo, Hu, Zeping, Jin, Hongchuan, Wang, Xian, Sun, Yi

“…Abnormal neddylation activation is frequently observed in human cancers and neddylation inhibition has been proposed as a therapy for cancer. Here, we report…”
Get full text

Sirt1 deacetylates and stabilizes p62 to promote hepato-carcinogenesis by Feng, Lifeng, Chen, Miaoqin, Li, Yiling, Li, Muchun, Hu, Shiman, Zhou, Bingluo, Zhu, Liyuan, Yu, Lei, Zhou, Qiyin, Tan, Linghui, An, Huimin, Wang, Xian, Jin, Hongchuan

“…p62/SQSTM1 is frequently up-regulated in many cancers including hepatocellular carcinoma. Highly expressed p62 promotes hepato-carcinogenesis by activating…”
Get full text

MLN4924: additional activities beyond neddylation inhibition by Zhou, Qiyin, Sun, Yi

“…MLN4924, a small molecular inhibitor of NEDD8 (neuronal precursor cell-expressed developmentally downregulated protein 8) activating enzyme (NAE), blocks…”
Get full text

LncRNA LINC00942 promotes chemoresistance in gastric cancer by suppressing MSI2 degradation to enhance c‐Myc mRNA stability by Zhu, Yiran, Zhou, Bingluo, Hu, Xinyang, Ying, Shilong, Zhou, Qiyin, Xu, Wenxia, Feng, Lifeng, Hou, Tianlun, Wang, Xian, Zhu, Liyuan, Jin, Hongchuan

“…Background Chemoresistance to cisplatin (DDP) remains a major challenge in advanced gastric cancer (GC) treatment. Although accumulating evidence suggests an…”
Get full text

Publisher Correction: Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3SPOP E3 ligase in cancer cells by Zhou, Qiyin, Lin, Wenyu, Wang, Chaoqun, Sun, Fei, Ju, Siwei, Chen, Qian, Wang, Yi, Chen, Yongxia, Li, Haomin, Wang, Linbo, Hu, Zeping, Jin, Hongchuan, Wang, Xian, Sun, Yi

Get full text

Synthetic lethality of glutaminolysis inhibition, autophagy inactivation and asparagine depletion in colon cancer by Li, Jiaqiu, Song, Ping, Zhu, Liyuan, Aziz, Neelum, Zhou, Qiyin, Zhang, Yulong, Xu, Wenxia, Feng, Lifeng, Chen, Dingwei, Wang, Xian, Jin, Hongchuan

“…Cancer cells reprogram metabolism to coordinate their rapid growth. They addict on glutamine metabolism for adenosine triphosphate generation and macromolecule…”
Get full text

Tumor response and survival in patients with advanced non-small-cell lung cancer: the predictive value of chemotherapy-induced changes in fibrinogen by Zhao, Jun, Zhao, Mingfang, Jin, Bo, Yu, Ping, Hu, Xuejun, Teng, Yuee, Zhang, Jingdong, Luo, Ying, Zhang, Lingyun, Zheng, Shuang, Zhou, Qiyin, Li, Heming, Liu, Yunpeng, Qu, Xiujuan

“…Hyperfibrinogenemia is a common problem associated with various carcinomas, and is accompanied by hypercoagulablity. In advanced non-small-cell lung cancer…”
Get full text

Hypoxia Stimulates SUMOylation-Dependent Stabilization of KDM5B by Zhou, Bingluo, Zhu, Yiran, Xu, Wenxia, Zhou, Qiyin, Tan, Linghui, Zhu, Liyuan, Chen, Hui, Feng, Lifeng, Hou, Tianlun, Wang, Xian, Chen, Dingwei, Jin, Hongchuan

“…Hypoxia is an important characteristic of the tumor microenvironment. Tumor cells can survive and propagate under the hypoxia stress by activating a series of…”
Get full text

CK1δ stimulates ubiquitination‐dependent proteasomal degradation of ATF4 to promote chemoresistance in gastric Cancer by Feng, Lifeng, Li, Muchun, Hu, Xinyang, Li, Yiling, Zhu, Liyuan, Chen, Miaoqin, Wei, Qi, Xu, Wenxia, Zhou, Qiyin, Wang, Weikai, Chen, Dingwei, Wang, Xian, Jin, Hongchuan

“…Chemoresistance remains a major obstacle to successful cancer therapy, especially for advanced cancers. It used to be recognised as a stable outcome resulting…”
Get full text

MTO1 worked as a modifier in the aminoglycosides sensitivity of yeast carrying a mitochondrial 15S rRNA C1477G mutation by Zhu, Xiaoyu, He, Xiangyu, Wang, Wei, Zhou, Qiyin, Yu, Zhe, Dai, Yu, Zhu, Xufen, Yan, Qingfeng

“…MTO1, together with MSS1 and MTO2, is a gene involved in the pathway of encoding a mitochondria-specific RNA-modifying enzyme related to the…”
Get full text

Mechanistic study on the nuclear modifier gene MSS1 mutation suppressing neomycin sensitivity of the mitochondrial 15S rRNA C1477G mutation in Saccharomyces cerevisiae by Zhou, Qiyin, Wang, Wei, He, Xiangyu, Zhu, Xiaoyu, Shen, Yaoyao, Yu, Zhe, Wang, Xuexiang, Qi, Xuchen, Zhang, Xuan, Fan, Mingjie, Dai, Yu, Yang, Shuxu, Yan, Qingfeng

“…The phenotypic manifestation of mitochondrial DNA (mtDNA) mutations can be modulated by nuclear genes and environmental factors. However, neither the…”
Get full text

CRL3 E3 ligase regulates glutamine and cystine metabolisms by Zhou, Qiyin, Li, Zhijian, Sun, Yi

Get full text

SLC7A11/xCT in cancer: biological functions and therapeutic implications by Lin, Wenyu, Wang, Chaoqun, Liu, Guangping, Bi, Chao, Wang, Xian, Zhou, Qiyin, Jin, Hongchuan

“…Amino acid transporters mediate substrates across cellular membranes and their fine-tuned regulations are critical to cellular metabolism, growth, and death…”
Get full text

LncRNAs regulate metabolism in cancer by Lin, Wenyu, Zhou, Qiyin, Wang, Chao-Qun, Zhu, Liyuan, Bi, Chao, Zhang, Shuzhen, Wang, Xian, Jin, Hongchuan

“…Metabolic reprogramming is a hallmark of cancer. Mammalian genome is characterized by pervasive transcription, generating abundant non-coding RNAs (ncRNAs)…”
Get full text

The CRL3KCTD10 ubiquitin ligase-USP18 axis coordinately regulates cystine uptake and ferroptosis by modulating SLC7A11 by Zhou, Qiyin, Yu, Hongfei, Chen, Yongxia, Ren, Jiayi, Lu, Yan, Sun, Yi

“…SLC7A11 is a cystine transporter and ferroptosis inhibitor. How the stability of SLC7A11 is coordinately regulated in response to environmental cystine by…”
Get full text

The CRL3 KCTD10 ubiquitin ligase-USP18 axis coordinately regulates cystine uptake and ferroptosis by modulating SLC7A11 by Zhou, Qiyin, Yu, Hongfei, Chen, Yongxia, Ren, Jiayi, Lu, Yan, Sun, Yi

“…SLC7A11 is a cystine transporter and ferroptosis inhibitor. How the stability of SLC7A11 is coordinately regulated in response to environmental cystine by…”
Get full text

New insight on the formation of uneven oxide scales on AFA steel in supercritical CO2: Roles of recrystallization degree on the high temperature corrosion resistance by Zhou, Qiyin, Chen, Jianye, Shi, Huigang, Zhang, Lefu, Huang, Yanping, Zhang, Gen, Zhao, Yongfu, Guo, Xianglong

“…Uneven oxide scale is a common phenomenon in high-temperature corrosion, but the formation mechanism has not been fully uncovered. A new alumina-forming…”
Get full text