Search Results - "Zhou, Qiang"
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Structure of the human LAT1–4F2hc heteromeric amino acid transporter complex
Published in Nature (London) (01-04-2019)“…The L-type amino acid transporter 1 (LAT1; also known as SLC7A5) catalyses the cross-membrane flux of large neutral amino acids in a sodium- and pH-independent…”
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Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
Published in Science (American Association for the Advancement of Science) (27-03-2020)“…Angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for severe acute respiratory syndrome-coronavirus (SARS-CoV) and the new coronavirus…”
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3
Historic Yangtze flooding of 2020 tied to extreme Indian Ocean conditions
Published in Proceedings of the National Academy of Sciences - PNAS (23-03-2021)“…Heavy monsoon rainfall ravaged a large swath of East Asia in summer 2020. Severe flooding of the Yangtze River displaced millions of residents in the midst of…”
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Journal Article -
4
Optimization of network flows for rural extension of fruit and vegetable agricultural technologies
Published in Applied mathematics and nonlinear sciences (01-01-2024)“…This paper focuses on the rural promotion of fruit and vegetable agricultural technology and proposes a network flow optimization model based on linear…”
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A Weakly-Supervised Framework for COVID-19 Classification and Lesion Localization From Chest CT
Published in IEEE transactions on medical imaging (01-08-2020)“…Accurate and rapid diagnosis of COVID-19 suspected cases plays a crucial role in timely quarantine and medical treatment. Developing a deep learning-based…”
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Ultrasmall Oxygen‐Deficient Bimetallic Oxide MnWOX Nanoparticles for Depletion of Endogenous GSH and Enhanced Sonodynamic Cancer Therapy
Published in Advanced materials (Weinheim) (01-06-2019)“…Sonodynamic therapy (SDT) triggered by ultrasound (US) has attracted increasing attention owing to its abilities to overcome critical limitations including low…”
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7
Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution
Published in Science (American Association for the Advancement of Science) (03-03-2017)“…Voltage-gated sodium (Na ) channels are responsible for the initiation and propagation of action potentials. They are associated with a variety of…”
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Journal Article -
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The BET bromodomain inhibitor JQ1 activates HIV latency through antagonizing Brd4 inhibition of Tat-transactivation
Published in Nucleic acids research (01-01-2013)“…Latent HIV reservoirs are the primary hurdle to eradication of infection. Identification of agents, pathways and molecular mechanisms that activate latent…”
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Phase-separation mechanism for C-terminal hyperphosphorylation of RNA polymerase II
Published in Nature (London) (01-06-2018)“…Hyperphosphorylation of the C-terminal domain (CTD) of the RPB1 subunit of human RNA polymerase (Pol) II is essential for transcriptional elongation and mRNA…”
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10
Phase separation of TAZ compartmentalizes the transcription machinery to promote gene expression
Published in Nature cell biology (01-04-2020)“…TAZ promotes growth, development and tumorigenesis by regulating the expression of target genes. However, the manner in which TAZ orchestrates the…”
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11
RNA Polymerase II Elongation Control
Published in Annual review of biochemistry (01-01-2012)“…Regulation of the elongation phase of transcription by RNA polymerase II (Pol II) is utilized extensively to generate the pattern of mRNAs needed to specify…”
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12
Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution
Published in Nature (London) (08-09-2016)“…The voltage-gated calcium (Ca v ) channels convert membrane electrical signals to intracellular Ca 2+ -mediated events. Among the ten subtypes of Ca v channel…”
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13
Structure of the Nav1.4-β1 Complex from Electric Eel
Published in Cell (27-07-2017)“…Voltage-gated sodium (Nav) channels initiate and propagate action potentials. Here, we present the cryo-EM structure of EeNav1.4, the Nav channel from electric…”
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14
Detection of COVID-19: A review of the current literature and future perspectives
Published in Biosensors & bioelectronics (15-10-2020)“…The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the coronavirus disease 2019 (COVID-19) worldwide pandemic. This…”
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15
Look at Boundary: A Boundary-Aware Face Alignment Algorithm
Published in 2018 IEEE/CVF Conference on Computer Vision and Pattern Recognition (01-06-2018)“…We present a novel boundary-aware face alignment algorithm by utilising boundary lines as the geometric structure of a human face to help facial landmark…”
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Conference Proceeding -
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Transfer of LncRNA CRNDE in TAM-derived exosomes is linked with cisplatin resistance in gastric cancer
Published in EMBO reports (06-12-2021)“…This study explores the role of the long noncoding RNA (LncRNA) CRNDE in cisplatin (CDDP) resistance of gastric cancer (GC) cells. Here, we show that LncRNA…”
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A neutralizing human antibody binds to the N-terminal domain of the Spike protein of SARS-CoV-2
Published in Science (American Association for the Advancement of Science) (07-08-2020)“…Developing therapeutics against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could be guided by the distribution of epitopes, not only on the…”
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The Control of HIV Transcription: Keeping RNA Polymerase II on Track
Published in Cell host & microbe (17-11-2011)“…Thirteen years ago, human cyclin T1 was identified as part of the positive transcription elongation factor b (P-TEFb) and the long-sought host cofactor for the…”
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Journal Article -
19
It's not mine: Anthropomorphism attenuates the effect of psychological ownership on product‐to‐self judgment
Published in Psychology & marketing (01-06-2023)“…Previous literature has shown that consumers often see themselves as possessing the characteristics of products they own, referring to product‐to‐self judgment…”
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Journal Article -
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Structural basis for the recognition of Sonic Hedgehog by human Patched1
Published in Science (American Association for the Advancement of Science) (10-08-2018)“…The Hedgehog (Hh) pathway involved in development and regeneration is activated by the extracellular binding of Hh to the membrane receptor Patched (Ptch). We…”
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