Search Results - "Zhou, Mengliang"

Protective Effects of Quercetin on Mitochondrial Biogenesis in Experimental Traumatic Brain Injury via the Nrf2 Signaling Pathway by Li, Xiang, Wang, Handong, Gao, Yongyue, Li, Liwen, Tang, Chao, Wen, Guodao, Zhou, Yuan, Zhou, Mengliang, Mao, Lei, Fan, Youwu

“…The present investigation was carried out to elucidate a possible molecular mechanism related to the protective effect of quercetin administration against…”
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LncRNA NEAT1 Enhances Glioma Progression via Regulating the miR-128-3p/ITGA5 Axis by Chen, Jiakai, Wang, Handong, Wang, Junjun, Niu, Wenhao, Deng, Chulei, Zhou, Mengliang

“…Accumulating evidences indicate that long non-coding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) promotes the progression of glioma. In this study,…”
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Resveratrol Attenuates Early Brain Injury after Experimental Subarachnoid Hemorrhage via Inhibition of NLRP3 Inflammasome Activation by Zhang, Xiangsheng, Wu, Qi, Zhang, Qingrong, Lu, Yue, Liu, Jingpeng, Li, Wei, Lv, Shengyin, Zhou, Mengliang, Zhang, Xin, Hang, Chunhua

“…Previous studies have demonstrated resveratrol (RSV) has beneficial effects in early brain injury (EBI) after subarachnoid hemorrhage (SAH). However, the…”
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Tetrahydrocurcumin provides neuroprotection in rats after traumatic brain injury: Autophagy and the PI3K/AKT pathways as a potential mechanism by Gao, Yongyue, MD, Li, Jie, MD, PhD, Wu, Lingyun, MD, PhD, Zhou, Chenhui, MD, PhD, Wang, Qiang, MD, PhD, Li, Xiang, MD, Zhou, Mengliang, MD, PhD, Wang, Handong, MD, PhD

“…Abstract Background Tetrahydrocurcumin provides neuroprotection in multiple neurological disorders by modulating oxidative stress, inflammatory responses and…”
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Nrf2 is required to maintain the self-renewal of glioma stem cells by Zhu, Jianhong, Wang, Handong, Sun, Qing, Ji, Xiangjun, Zhu, Lin, Cong, Zixiang, Zhou, Yuan, Liu, Huandong, Zhou, Mengliang

“…Glioblastomas are deadly cancers that display a functional cellular hierarchy maintained by self-renewing glioma stem cells (GSCs). Self-renewal is a complex…”
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Valproic Acid Attenuates Traumatic Brain Injury-Induced Inflammation in Vivo : Involvement of Autophagy and the Nrf2/ARE Signaling Pathway by Chen, Xiangrong, Wang, Handong, Zhou, Mengliang, Li, Xiang, Fang, Zhongning, Gao, Hongzhi, Li, Yasong, Hu, Weipeng

“…Microglial activation and the inflammatory response in the central nervous system (CNS) play important roles in secondary damage after traumatic brain injury…”
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dl-3-n-Butylphthalide (NBP) Provides Neuroprotection in the Mice Models After Traumatic Brain Injury via Nrf2-ARE Signaling Pathway by Liu, Zhengwei, Wang, Handong, Shi, Xiaofeng, Li, Liwen, Zhou, Mengliang, Ding, Hui, Yang, Youqing, Li, Xiang, Ding, Ke

“…The present study was aimed to evaluate the neuroprotective effects of NBP in the mice models of TBI, as well as the possible role of Nrf2-ARE pathways in the…”
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Baicalin Protects Mice Brain From Apoptosis in Traumatic Brain Injury Model Through Activation of Autophagy by Fang, Jiang, Zhu, Yihao, Wang, Handong, Cao, Bailu, Fei, Maoxing, Niu, Wenhao, Zhou, Yuan, Wang, Xiaoliang, Li, Xiang, Zhou, Mengliang

“…Autophagy is associated with secondary injury following traumatic brain injury (TBI) and is expected to be a therapeutic target. Baicalin, a neuroprotective…”
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Correction to: Nrf2 is required to maintain the self-renewal of glioma stem cells by Zhu, Jianhong, Wang, Handong, Sun, Qing, Ji, Xiangjun, Zhu, Lin, Cong, Zixiang, Zhou, Yuan, Liu, Huandong, Zhou, Mengliang

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A Modified Treatment Through Point-to-Point Coil Embolization for Direct Carotid Cavernous to Fistula: A Single-Center Result by Zhang, Zihuan, Liu, Jiaqiang, Zhang, Bingbing, Zhou, Mengliang, Zhao, Xintong, Li, Zhenbao

“…This study aims to assess the safety and efficacy of the modified treatment through point-to-point coil embolization of direct carotid cavernous fistula…”
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Cyclosporin A ameliorates early brain injury after subarachnoid hemorrhage through inhibition of a Nur77 dependent apoptosis pathway by Dai, Yuxiang, Sun, Qing, Zhang, Xing, Hu, Yangchun, Zhou, Mengliang, Shi, Jixin

“…Abstract Nur77 is a potent pro-apoptotic member of the orphan nuclear receptor superfamily. It has been demonstrated that can mediate apoptosis in many system…”
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Genetic elimination of Nrf2 aggravates secondary complications except for vasospasm after experimental subarachnoid hemorrhage in mice by Li, Tao, Wang, Handong, Ding, Yu, Zhou, Mengliang, Zhou, Xiaoming, Zhang, Xiangshen, Ding, Ke, He, Jin, Lu, Xinyu, Xu, Jianguo, Wei, Wuting

“…Abstract Nuclear factor erythroid 2-related factor 2 (Nrf2) is a key endogenous protective regulator in the body. This study aimed to explore the role of Nrf2…”
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TREM2 Alleviates Subarachnoid Hemorrhage-Induced Brain Injury through Attenuating Neuroinflammation and Programmed Cell Death in Vivo and in Vitro by Liu, Jiaqiang, Zhang, Zihuan, Zhou, Mengliang, Ling, Shizhang, Zhou, Xiaoming, Yuan, Bin, Zhao, Xintong, Qi, Min, Han, Yanling, Qin, Feiyun, Li, Zhenbao

“…Apoptosis and pyroptosis are two types of programmed cell death related to the neuroinflammatory reaction after subarachnoid hemorrhage (SAH). Research…”
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Glycyrrhizic acid confers neuroprotection after subarachnoid hemorrhage via inhibition of high mobility group box-1 protein: A hypothesis for novel therapy of subarachnoid hemorrhage by Sun, Qing, Wang, Fan, Li, Wei, Li, Weide, Hu, Yang-chun, Li, Song, Zhu, Jian-hong, Zhou, Mengliang, Hang, Chun-hua

“…Abstract Subarachnoid hemorrhage usually results in poor clinical outcome and devastating neurological deficits. The early brain injury and delayed vasospasm…”
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Differential Nrf2 expression between glioma stem cells and non-stem-like cells in glioblastoma by ZHU, JIANHONG, WANG, HANDONG, JI, XIANGJUN, ZHU, LIN, SUN, QING, CONG, ZIXIANG, ZHOU, YUAN, LIU, HUANDONG, ZHOU, MENGLIANG

“…Glioblastoma multiforme (GBM), the most commonly occurring primary intracranial tumor, is associated with a negative outcome, regardless of the availability of…”
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Curcumin provides neuroprotection in model of traumatic brain injury via the Nrf2-ARE signaling pathway by Dai, Wei, Wang, Handong, Fang, Jiang, Zhu, Yihao, Zhou, Jian, Wang, Xiaoliang, Zhou, Yuan, Zhou, Mengliang

“…•Curcumin attenuated secondary brain injury induced by TBI in mice.•Curcumin promoted Nrf2 translocation from cytoplasm to nucleus.•Curcumin enhanced Nrf2…”
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Cognitive assessment in Chinese patients with aneurysmal subarachnoid hemorrhage by Cheng, Huilin, Shi, Jixin, Zhou, Mengliang

“…A subgroup of patients who survive aneurysmal subarachnoid hemorrhage (SAH) may have significant cognitive deficits. The aim of the current study was to…”
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Melatonin stimulates antioxidant enzymes and reduces oxidative stress in experimental traumatic brain injury: the Nrf2–ARE signaling pathway as a potential mechanism by Ding, Ke, Wang, Handong, Xu, Jianguo, Li, Tao, Zhang, Li, Ding, Yu, Zhu, Lin, He, Jin, Zhou, Mengliang

“…The goal of this study was to evaluate the potential involvement of melatonin in the activation of the nuclear factor erythroid 2-related factor 2 and…”
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Podoplanin influences the inflammatory phenotypes and mobility of microglia in traumatic brain injury by Fei, Maoxing, Wang, Handong, Zhou, Mengliang, Deng, Chulei, Zhang, Li, Han, Yanling

“…Traumatic brain injury (TBI) represents a major cause of death and disability worldwide. Exacerbated neuroinflammation following TBI causes secondary injury…”
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Metabotropic glutamate receptor 5 upregulation of γ-aminobutyric acid transporter 3 expression ameliorates cognitive impairment after traumatic brain injury in mice by Xu, Peng, Huang, Xiwen, Niu, Wenhao, Yu, Dong, Zhou, Mengliang, Wang, Hangdong

“…Traumatic brain injury (TBI) causes neurotransmitter disturbances contributing to neuronal cell death and neurological deficits. In humans, brain injuries…”
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