Search Results - "Zhou, Maojun"
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Research on a new method to optimize the thermal characteristics of an engine nacelle cooling module
Published in Journal of mechanical science and technology (01-05-2023)“…Heat reflow in the fan rotation center of a forced convection cooling system has a great influence on heat dissipation. In this research, a calculation model…”
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Insertions and Deletions Play an Important Role in the Diversity of Conotoxins
Published in The Protein Journal (01-04-2020)“…Previous studies have indicated that each conotoxin precursor has a hyperconserved signal region, a rather conserved pro region and a hypervariable mature…”
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A comprehensive study on the impacts of isolation heat exchangers on the energy performance of surface water heat pump systems
Published in Geothermics (01-06-2023)“…•Development of energy performance models for indirect and direct surface water heat pump systems.•A method for energy-saving judgment between indirect and…”
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Combination of mesenchymal stem cell injection with icariin for the treatment of diabetes-associated erectile dysfunction
Published in PloS one (28-03-2017)“…The present study was aimed to examine whether icariin, a traditional Chinese medicine, could improve therapeutic effects of adipose derived mesenchymal stem…”
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Phosphorylation of Bcl-2 plays an important role in glycochenodeoxycholate-induced survival and chemoresistance in HCC
Published in Oncology reports (01-09-2017)“…Hepatocellular carcinoma (HCC) is a highly malignant tumor and can evolve rapidly to resistance to chemotherapies. Glycochenodeoxycholate (GCDA), which is…”
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Suppressing ERK Pathway Impairs Glycochenodeoxycholate-Mediated Survival and Drug-Resistance in Hepatocellular Carcinoma Cells
Published in Frontiers in oncology (13-07-2021)“…Glycochenodeoxycholate (GCDA), a toxic component in bile salts, is involved in carcinogenesis of gastrointestinal tumors. The objective of this research was to…”
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A novel proline-rich M-superfamily conotoxin that can simultaneously affect sodium, potassium and calcium currents
Published in The journal of venomous animals and toxins including tropical diseases (2021)“…Conotoxins have become a research hotspot in the neuropharmacology field for their high activity and specificity in targeting ion channels and neurotransmitter…”
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O1-conotoxin Tx6.7 cloned from the genomic DNA of Conus textile that inhibits calcium currents
Published in The journal of venomous animals and toxins including tropical diseases (2023)“…Conotoxins exhibit great potential as neuropharmacology tools and therapeutic candidates due to their high affinity and specificity for ion channels,…”
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Molecular evolution and diversity of Conus peptide toxins, as revealed by gene structure and intron sequence analyses
Published in PloS one (13-12-2013)“…Cone snails, which are predatory marine gastropods, produce a cocktail of venoms used for predation, defense and competition. The major venom component,…”
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Economic and Environmental Optimization for Distributed Energy System Integrated with District Energy Network
Published in Energies (Basel) (2019)“…The purpose of this research is to develop a mixed integer linear programming model for optimization of a distributed energy system integrated with electricity…”
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Structure–function relationship of conotoxin lt14a, a potential analgesic with low cytotoxicity
Published in Peptides (New York, N.Y. : 1980) (01-02-2011)“…▶ Determined the solution structure of conotoxin lt14a by NMR. ▶ An analog [K7A]-lt14a exhibited higher activity than lt14a as long-lasting analgesic. ▶ Both…”
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Identification of a novel M-superfamily conotoxin with the ability to enhance tetrodotoxin sensitive sodium currents
Published in Archives of toxicology (01-10-2009)“…In this work, a novel M-superfamily conotoxin, designated lt3a, was purified from the crude venom of Conus litteratus. Combined with peptide sequencing,…”
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Isolation and characterization of a T-superfamily conotoxin from Conus litteratus with targeting tetrodotoxin-sensitive sodium channels
Published in Peptides (New York, N.Y. : 1980) (01-12-2007)“…A T-1-conotoxin, lt5d, was purified and characterized from the venom of vermivorous hunting cone snails Conus litteratus. The complete amino acid sequence of…”
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Production and characterization of a novel antimicrobial peptide HKABF by Pichia pastoris
Published in Process biochemistry (1991) (01-10-2008)“…HKABF, Hippocampus kuda antibacterial factor, is a putative antimicrobial peptide identified from the cDNA library of the brooding pouch of H. kuda Bleeker…”
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μ-conotoxin TsIIIA, a peptide inhibitor of human voltage-gated sodium channel hNav1.8
Published in Toxicon (Oxford) (30-10-2020)“…TsIIIA, the first μ-conotoxin from Conus tessulatus, can selectively inhibit rat tetrodotoxin-resistant sodium channels. TsIIIA also shows potent analgesic…”
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“Before Dawn,” Listening to the Voices of Social Media: A Study on the Public’s Response to the COVID-19 Vaccine
Published in Journal of environmental and public health (2022)“…The COVID-19 pandemic is a worldwide catastrophe. In the absence of an effective drug, one effective measure to pull the pandemic to the end is herd immunity…”
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Synthesis and evaluation of a novel analgesic conotoxin Lt7b that inhibits calcium currents and increases sodium currents
Published in Journal of cellular and molecular medicine (01-10-2022)“…Conotoxins are promising neuropharmacological tools and drug candidates due to their high efficiency and specificity in targeting ion channels or…”
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Synthesis and characterization of αM-conotoxin SIIID, a reversible human α7 nicotinic acetylcholine receptor antagonist
Published in Toxicon (Oxford) (30-04-2022)“…α-Conotoxins, a group of small marine peptide toxins that target nAChRs with high potency and selectivity, are valuable pharmacological tools and potential…”
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Gut microbiota regulates the ALK5/NOX1 axis by altering glutamine metabolism to inhibit ferroptosis of intrahepatic cholangiocarcinoma cells
Published in Biochimica et biophysica acta. Molecular basis of disease (01-06-2024)“…Intrahepatic cholangiocarcinoma (ICC) is a kind of hepatobiliary tumor that is increasing in incidence and mortality. The gut microbiota plays a role in the…”
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Inhibitory and anti‐inflammatory effects of two antimicrobial peptides moronecidin and temporin‐1Dra against Propionibacterium acnes in vitro and in vivo
Published in Journal of peptide science (01-07-2020)“…Proliferation of Propionibacterium acnes (P. acnes) is one of the main pathogenetic mechanisms of acne. Antimicrobial peptides with low‐drug resistance and…”
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