Search Results - "Zhou, Luwen"
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Microtubule-Mediated Wall Anisotropy Contributes to Leaf Blade Flattening
Published in Current biology (19-10-2020)“…Plant organs can adopt a wide range of shapes, resulting from highly directional cell growth and divisions. We focus here on leaves and leaf-like organs in…”
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Dissipative particle dynamics simulation of cell entry into a micro-channel
Published in Engineering analysis with boundary elements (01-10-2019)“…Cell deformability is an important biomarker which can be used to distinguish and sort between healthy and cancer cells. In this paper, we presented a…”
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Mechanical remodeling of normally sized mammalian cells under a gravity vector
Published in The FASEB journal (01-02-2017)“…ABSTRACT Translocation of the dense nucleus along a gravity vector initiates mechanical remodeling of a cell, but the underlying mechanisms of cytoskeletal…”
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4
Numerical simulation of flow characteristics in a permeable liver sinusoid with leukocytes
Published in Biophysical journal (06-12-2022)“…Double-layered channels of sinusoid lumen and Disse space separated by fenestrated liver sinusoidal endothelial cells (LSECs) endow the unique mechanical…”
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Flow field analyses of a porous membrane-separated, double-layered microfluidic chip for cell co-culture
Published in Acta mechanica Sinica (01-06-2020)“…Organs-on-chips composed of a porous membrane-separated, double-layered channels are used widely in elucidating the effects of cell co-culture and flow shear…”
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Super‐Amphiphilic Na2Ti3O7 Nanofibrous Film Enabling Water–Oil Miscibility
Published in Advanced materials interfaces (14-11-2022)“…Due to their extraordinary affinity for both water and oil, super‐amphiphilic materials have garnered considerable interest. A Na2Ti3O7 (NTO) film with…”
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Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay
Published in Vaccine (29-07-2016)“…Abstract Malaria transmission-blocking vaccines (TBVs) are potentially helpful tools for malaria eradication. The standard membrane-feeding assay (SMFA) is…”
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A human-serum-free medium can induce more infectious P. falciparum gametocytes than a conventional human-serum-containing medium
Published in Scientific reports (27-09-2024)“…Malaria remains a global health problem, and the standard membrane feeding assay (SMFA) is a key functional assay for development of new interventions to stop…”
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9
Salt bridge interactions within the β2 integrin α7 helix mediate force‐induced binding and shear resistance ability
Published in The FEBS journal (01-01-2018)“…The functional performance of the αI domain α7 helix in β2 integrin activation depends on the allostery of the α7 helix, which axially slides down; therefore,…”
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Theoretical modeling of mechanical homeostasis of a mammalian cell under gravity-directed vector
Published in Biomechanics and modeling in mechanobiology (01-02-2018)“…Translocation of dense nucleus along gravity vector initiates mechanical remodeling of a eukaryotic cell. In our previous experiments, we quantified the impact…”
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Elucidating functional epitopes within the N-terminal region of malaria transmission blocking vaccine antigen Pfs230
Published in npj vaccines (13-01-2022)“…Pfs230 is a leading malaria transmission blocking vaccine (TBV) candidate. Comprising 3135 amino acids (aa), the large size of Pfs230 necessitates the use of…”
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12
Reply to ‘Early shaping of a leaf’
Published in Nature plants (01-09-2018)Get full text
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13
Strong concordance between percent inhibition in oocyst and sporozoite intensities in a Plasmodium falciparum standard membrane-feeding assay
Published in Parasites & vectors (06-05-2019)“…Effective malaria transmission-blocking vaccines (TBVs) can support malaria eradication programmes, and the standard membrane-feeding assay (SMFA) has been…”
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Dissipative particle dynamics simulation of flow through periodic arrays of circular micropillar
Published in Applied mathematics and mechanics (01-11-2016)“…Flow through arrays of micropillar embedded inside microfluidic chip systems is important for various microfluidic devices. It is critical to accurately…”
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15
Vaccine co-display of CSP and Pfs230 on liposomes targeting two Plasmodium falciparum differentiation stages
Published in Communications biology (01-08-2022)“…A vaccine targeting multiple stages of the Plasmodium falciparum parasite life cycle is desirable. The sporozoite surface Circumsporozoite Protein (CSP) is the…”
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Epidermal restriction confers robustness to organ shapes
Published in Journal of integrative plant biology (01-12-2020)“…The shape of comparable tissues and organs is consistent among individuals of a given species, but how this consistency or robustness is achieved remains an…”
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Two Complementary Signaling Pathways Depict Eukaryotic Chemotaxis: A Mechanochemical Coupling Model
Published in Frontiers in cell and developmental biology (17-11-2021)“…Many eukaryotic cells, including neutrophils and Dictyostelium cells, are able to undergo correlated random migration in the absence of directional cues while…”
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Identification of domains within Pfs230 that elicit transmission blocking antibody responses
Published in Vaccine (22-03-2019)“…•30 recombinant proteins, which covered the entire Pfs230 molecule, were expressed.•Antibodies against each construct were tested by Western blot, IFA and…”
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Engineering of a plant-produced virus-like particle to improve the display of the Plasmodium falciparum Pfs25 antigen and transmission-blocking activity of the vaccine candidate
Published in Vaccine (23-01-2023)“…Malaria kills around 409,000 people a year, mostly children under the age of five. Malaria transmission-blocking vaccines work to reduce malaria prevalence in…”
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ELISA units, IgG subclass ratio and avidity determined functional activity of mouse anti-Pfs230 antibodies judged by a standard membrane-feeding assay with Plasmodium falciparum
Published in Vaccine (03-04-2019)“…•Multiple mouse anti-Pfs230 antibodies were generated for ELISA and SMFA tests.•There was a significant correlation between ELISA titer and SMFA…”
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