Search Results - "Zhou, Leiji"
-
1
Distance-based microfluidic quantitative detection methods for point-of-care testing
Published in Lab on a chip (07-04-2016)“…Equipment-free devices with quantitative readout are of great significance to point-of-care testing (POCT), which provides real-time readout to users and is…”
Get more information
Journal Article -
2
Recent Progress in Aptamer-Based Functional Probes for Bioanalysis and Biomedicine
Published in Chemistry : a European journal (11-07-2016)“…Nucleic acid aptamers are short synthetic DNA or RNA sequences that can bind to a wide range of targets with high affinity and specificity. In recent years,…”
Get full text
Journal Article -
3
A Novel Label-Free Electrochemical Immunosensor for the Detection of Thyroid Transcription Factor 1 Using Ribbon-like Tungsten Disulfide-Reduced Graphene Oxide Nanohybrids and Gold Nanoparticles
Published in Molecules (Basel, Switzerland) (01-01-2024)“…Thyroid transcription factor 1 (TTF1) is an important cancer-related biomarker for clinical diagnosis, especially for carcinomas of lung and thyroid origin…”
Get full text
Journal Article -
4
A Logical Molecular Circuit for Programmable and Autonomous Regulation of Protein Activity Using DNA Aptamer–Protein Interactions
Published in Journal of the American Chemical Society (26-12-2012)“…Researchers increasingly envision an important role for artificial biochemical circuits in biological engineering, much like electrical circuits in electrical…”
Get full text
Journal Article -
5
DNA-Mediated Morphological Control of Silver Nanoparticles
Published in Small (Weinheim an der Bergstrasse, Germany) (01-10-2016)“…It is demonstrated that DNA can be used to control the synthesis of silver nanoplates with different morphologies using spherical silver seeds. UV–vis…”
Get full text
Journal Article -
6
Quantitative Intracellular Molecular Profiling Using a One-Dimensional Flow System
Published in Analytical chemistry (Washington) (01-09-2006)“…We report on the development of one-dimensional microfluidic bead arrays for rapid and quantitative molecular profiling of human cancer cells. This new…”
Get full text
Journal Article -
7
Detection of single-base mutations using 1-D microfluidic beads array
Published in Electrophoresis (01-12-2007)“…The application of a 1-D microfluidic beads array that is composed of individually addressable functionalized SiO₂ beads has been demonstrated for detection of…”
Get full text
Journal Article -
8
One-dimensional microfluidic beads array for multiple mRNAs expression detection
Published in Biosensors & bioelectronics (15-05-2007)“…A one-dimensional microfluidic beads array for in vitro rapid measurement of multiple mRNAs expression is presented in this paper. Gene specific capture…”
Get full text
Journal Article -
9
Improving the performance of immobilized molecular beacons through cleavage
Published in Analytica chimica acta (17-05-2006)“…Surface-immobilized molecular beacons (MBs) usually have relatively low fluorescence enhancement after hybridization, which causes significant limitations to…”
Get full text
Journal Article -
10
Highly Sensitive and Automated Surface Enhanced Raman Scattering-based Immunoassay for H5N1 Detection with Digital Microfluidics
Published in Analytical chemistry (Washington) (17-04-2018)“…Digital microfluidics (DMF) is a powerful platform for a broad range of applications, especially immunoassays having multiple steps, due to the advantages of…”
Get full text
Journal Article -
11
Design and synthesis of target-responsive hydrogel for portable visual quantitative detection of uranium with a microfluidic distance-based readout device
Published in Biosensors & bioelectronics (15-11-2016)“…Due to uranium's increasing exploitation in nuclear energy and its toxicity to human health, it is of great significance to detect uranium contamination. In…”
Get full text
Journal Article -
12
Sensitive and automated detection of bacteria by CRISPR/Cas12a-assisted amplification with digital microfluidics
Published in Sensors and actuators. B, Chemical (15-04-2023)“…The development of new diagnostic platforms for sensitive and rapid detection of bacterial pathogens is of great significance for improving precision…”
Get full text
Journal Article -
13
A fully integrated distance readout ELISA-Chip for point-of-care testing with sample-in-answer-out capability
Published in Biosensors & bioelectronics (15-10-2017)“…Enzyme-linked immunosorbent assay (ELISA) is a popular laboratory technique for detection of disease-specific protein biomarkers with high specificity and…”
Get full text
Journal Article -
14
Berberine-doped montmorillonite nanosheet for photoenhanced antibacterial therapy and wound healing
Published in Journal of colloid and interface science (15-12-2024)“…Design and synthesis of BBR@MMT for the treatment of bacterial infected wounds. BBR@MMT is used for bacteriostasis through its photodynamic antimicrobial…”
Get full text
Journal Article -
15
A portable visual detection method based on a target-responsive DNA hydrogel and color change of gold nanorods
Published in Chemical communications (Cambridge, England) (08-06-2017)“…A new method based on a functional DNA crosslinked hydrogel as a target-responsive unit and gold nanorods (AuNRs) as a multicolor signal readout circuit was…”
Get more information
Journal Article -
16
Auto-affitech: an automated ligand binding affinity evaluation platform using digital microfluidics with a bidirectional magnetic separation method
Published in Lab on a chip (05-05-2020)“…The dissociation constant (Kd) is a crucial parameter for characterizing binding affinity in molecular recognition, including antigen-antibody, DNA-protein,…”
Get more information
Journal Article -
17
Highly sensitive and selective detection of miRNA: DNase I-assisted target recycling using DNA probes protected by polydopamine nanospheres
Published in Chemical communications (Cambridge, England) (01-01-2015)“…Based on the protective properties of polydopamine nanospheres for DNA probes against nuclease digestion, we have developed a DNase I-assisted target recycling…”
Get more information
Journal Article -
18
Portable visual quantitative detection of aflatoxin B1 using a target-responsive hydrogel and a distance-readout microfluidic chip
Published in Lab on a chip (2016)“…Aflatoxin B1 (AFB1), as the secondary metabolite of molds, is the most predominant and toxic mycotoxin that seriously threatens the health of humans and…”
Get more information
Journal Article -
19
Aptamer‐Assisted Blockade of the Immune Suppressor Sialic Acid‐Binding Immunoglobulin‐Like Lectin‐15 for Cancer Immunotherapy
Published in Angewandte Chemie International Edition (21-12-2023)“…The percentage of low response and adaptive resistance to current antibody‐based immune checkpoint blockade (ICB) therapy requires the development of novel…”
Get full text
Journal Article -
20
Digital-WGS: Automated, highly efficient whole-genome sequencing of single cells by digital microfluidics
Published in Science advances (01-12-2020)“…Single-cell whole-genome sequencing (WGS) is critical for characterizing dynamic intercellular changes in DNA. Current sample preparation technologies for…”
Get full text
Journal Article