Search Results - "Zhou, Joseph X."

Single-cell gene expression profiling and cell state dynamics: collecting data, correlating data points and connecting the dots by Marr, Carsten, Zhou, Joseph X, Huang, Sui

“…Graphical abstract…”
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Cell population structure prior to bifurcation predicts efficiency of directed differentiation in human induced pluripotent cells by Bargaje, Rhishikesh, Trachana, Kalliopi, Shelton, Martin N., McGinnis, Christopher S., Zhou, Joseph X., Chadick, Cora, Cook, Savannah, Cavanaugh, Christopher, Huang, Sui, Hood, Leroy

“…Steering the differentiation of induced pluripotent stem cells (iPSCs) toward specific cell types is crucial for patient-specific disease modeling and drug…”
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Cellular network entropy as the energy potential in Waddington's differentiation landscape by Banerji, Christopher R. S., Miranda-Saavedra, Diego, Severini, Simone, Widschwendter, Martin, Enver, Tariq, Zhou, Joseph X., Teschendorff, Andrew E.

“…Differentiation is a key cellular process in normal tissue development that is significantly altered in cancer. Although molecular signatures characterising…”
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Understanding gene circuits at cell-fate branch points for rational cell reprogramming by Zhou, Joseph X, Huang, Sui

“…Cell-type reprogramming, the artificial induction of a switch of cell lineage and developmental stage, holds great promise for regenerative medicine. However,…”
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Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes by Zhou, Joseph X., Taramelli, Roberto, Pedrini, Edoardo, Knijnenburg, Theo, Huang, Sui

“…Many behaviors of cancer, such as progression, metastasis and drug resistance etc., cannot be fully understood by genetic mutations or intracellular signaling…”
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Cell population growth kinetics in the presence of stochastic heterogeneity of cell phenotype by Wang, Yue, Zhou, Joseph X., Pedrini, Edoardo, Rubin, Irit, Khalil, May, Taramelli, Roberto, Qian, Hong, Huang, Sui

“…Recent studies at individual cell resolution have revealed phenotypic heterogeneity in nominally clonal tumor cell populations. The heterogeneity affects cell…”
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Determining Relative Dynamic Stability of Cell States Using Boolean Network Model by Joo, Jae Il, Zhou, Joseph X., Huang, Sui, Cho, Kwang-Hyun

“…Cell state transition is at the core of biological processes in metazoan, which includes cell differentiation, epithelial-to-mesenchymal transition (EMT) and…”
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Processes on the emergent landscapes of biochemical reaction networks and heterogeneous cell population dynamics: differentiation in living matters by Huang, Sui, Li, Fangting, Zhou, Joseph X., Qian, Hong

“…The notion of an attractor has been widely employed in thinking about the nonlinear dynamics of organisms and biological phenomena as systems and as processes…”
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Evaluation of Stein-O'Brien et al.: To See a World in a Grain of Sand-How to Reveal a Common Latent Space through Multiple Platform Omics Data by Zhou, Joseph X

“…One snapshot of the peer review process for "Decomposing Cell Identity for Transfer Learning across Cellular Measurements, Platforms, Tissues, and Species"…”
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Author Correction: Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes by Zhou, Joseph X., Taramelli, Roberto, Pedrini, Edoardo, Knijnenburg, Theo, Huang, Sui

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper…”
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Systematic drug perturbations on cancer cells reveal diverse exit paths from proliferative state by Zhou, Joseph X, Isik, Zerrin, Xiao, Caide, Rubin, Irit, Kauffman, Stuart A, Schroeder, Michael, Huang, Sui

“…During a cell state transition, cells travel along trajectories in a gene expression state space. This dynamical systems framework complements the traditional…”
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Dr. Joseph Zhou by Zhou, Joseph X.

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Cell Population Growth Kinetics in the Presence of Stochastic Heterogeneity of Cell Phenotype by Wang, Yue, Zhou, Joseph X, Pedrini, Edoardo, Rubin, Irit, Khalil, May, Taramelli, Roberto, Qian, Hong, Huang, Sui

“…Recent studies at individual cell resolution have revealed phenotypic heterogeneity in nominally clonal tumor cell populations. The heterogeneity affects cell…”
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Cellular network entropy as the energy potential in Waddington's differentiation landscape by Banerji, Christopher R. S, Miranda-Saavedra, Diego, Severini, Simone, Widschwendter, Martin, Enver, Tariq, Zhou, Joseph X, Teschendorff, Andrew E

“…Scientific Reports (2013) 3, 3039 Differentiation is a key cellular process in normal tissue development that is significantly altered in cancer. Although…”
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