Search Results - "Zhou, Jiangbing"

Targeted Delivery of CRISPR/Cas9‐Mediated Cancer Gene Therapy via Liposome‐Templated Hydrogel Nanoparticles by Chen, Zeming, Liu, Fuyao, Chen, Yanke, Liu, Jun, Wang, Xiaoying, Chen, Ann T., Deng, Gang, Zhang, Hongyi, Liu, Jie, Hong, Zhangyong, Zhou, Jiangbing

“…Due to its simplicity, versatility, and high efficiency, the clustered regularly interspaced short palindromic repeat (CRISPR)/Cas9 technology has emerged as…”
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Thermosensitive Exosome–Liposome Hybrid Nanoparticle‐Mediated Chemoimmunotherapy for Improved Treatment of Metastatic Peritoneal Cancer by Lv, Qijun, Cheng, Lili, Lu, Yao, Zhang, Xiaoge, Wang, Yizhen, Deng, Junfeng, Zhou, Jiangbing, Liu, Bo, Liu, Jie

“…Metastatic peritoneal carcinoma (mPC) is a deadly disease without effective treatment. To improve treatment of this disease, a recently developed hyperthermic…”
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Targeted tumour theranostics in mice via carbon quantum dots structurally mimicking large amino acids by Li, Shuhua, Su, Wen, Wu, Hao, Yuan, Ting, Yuan, Chang, Liu, Jun, Deng, Gang, Gao, Xingchun, Chen, Zeming, Bao, Youmei, Yuan, Fanglong, Zhou, Shixin, Tan, Hongwei, Li, Yunchao, Li, Xiaohong, Fan, Louzhen, Zhu, Jia, Chen, Ann T., Liu, Fuyao, Zhou, Yu, Li, Miao, Zhai, Xingchen, Zhou, Jiangbing

“…Strategies for selectively imaging and delivering drugs to tumours typically leverage differentially upregulated surface molecules on cancer cells. Here, we…”
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Thrombin-Responsive, Brain-Targeting Nanoparticles for Improved Stroke Therapy by Guo, Xing, Deng, Gang, Liu, Jun, Zou, Pan, Du, Fengyi, Liu, Fuyao, Chen, Ann T, Hu, Rui, Li, Miao, Zhang, Shenqi, Tang, Zhishu, Han, Liang, Liu, Jie, Sheth, Kevin N, Chen, Qianxue, Gou, Xingchun, Zhou, Jiangbing

“…Current treatments for ischemic stroke are insufficient. The lack of effective pharmacological approaches can be mainly attributed to the difficulty in…”
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Targeted drug delivery to ischemic stroke via chlorotoxin-anchored, lexiscan-loaded nanoparticles by Han, Liang, PhD, Cai, Qiang, MD, Tian, Daofeng, MD, Kong, Derek K., MS, Gou, Xingchun, PhD, Chen, Zeming, BS, Strittmatter, Stephen M., MD, PhD, Wang, Zuoheng, PhD, Sheth, Kevin N., MD, Zhou, Jiangbing, PhD

“…Abstract Ischemic stroke is a leading cause of disability and death worldwide. Current drug treatment for stroke remains inadequate due to the existence of the…”
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ZNF117 regulates glioblastoma stem cell differentiation towards oligodendroglial lineage by Liu, Jun, Wang, Xiaoying, Chen, Ann T., Gao, Xingchun, Himes, Benjamin T., Zhang, Hongyi, Chen, Zeming, Wang, Jianhui, Sheu, Wendy C., Deng, Gang, Xiao, Yang, Zou, Pan, Zhang, Shenqi, Liu, Fuyao, Zhu, Yong, Fan, Rong, Patel, Toral R., Saltzman, W. Mark, Zhou, Jiangbing

“…Glioblastoma (GBM) is a deadly disease without effective treatment. Because glioblastoma stem cells (GSCs) contribute to tumor resistance and recurrence,…”
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Highly penetrative, drug-loaded nanocarriers improve treatment of glioblastoma by Zhou, Jiangbing, Patel, Toral R., Sirianni, Rachael W., Strohbehn, Garth, Zheng, Ming-Qiang, Duong, Nha, Schafbauer, Thomas, Huttner, Anita J., Huang, Yiyun, Carson, Richard E., Zhang, Ying, Sullivan, David J., Piepmeier, Joseph M., Saltzman, W. Mark

“…Current therapy for glioblastoma multiforme is insufficient, with nearly universal recurrence. Available drug therapies are unsuccessful because they fail to…”
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Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance by Zhou, Jiangbing, Wulfkuhle, Julia, Zhang, Hao, Gu, Peihua, Yang, Yanqin, Deng, Jianghong, Margolick, Joseph B, Liotta, Lance A, Petricoin, Emanuel III, Zhang, Ying

“…Side-population (SP) cells within cancers and cell lines are rare cell populations known to enrich cancer stem-like cells. In this study, we characterized SP…”
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Increased Nanoparticle Delivery to Brain Tumors by Autocatalytic Priming for Improved Treatment and Imaging by Han, Liang, Kong, Derek K, Zheng, Ming-qiang, Murikinati, Sasidhar, Ma, Chao, Yuan, Peng, Li, Liyuan, Tian, Daofeng, Cai, Qiang, Ye, Chunlin, Holden, Daniel, Park, June-Hee, Gao, Xiaobin, Thomas, Jean-Leon, Grutzendler, Jaime, Carson, Richard E, Huang, Yiyun, Piepmeier, Joseph M, Zhou, Jiangbing

“…The blood–brain barrier (BBB) is partially disrupted in brain tumors. Despite the gaps in the BBB, there is an inadequate amount of pharmacological agents…”
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Cancer stem cells: Models, mechanisms and implications for improved treatment by Zhou, Jiangbing, Zhang, Ying

“…Cancer stem cell research has drawn a lot of attention recently. The importance of cancer stem cell research lies in the possibility of providing new…”
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Single small molecule-assembled nanoparticles mediate efficient oral drug delivery by Yang, Xin, Ma, Chao, Chen, Zeming, Liu, Jun, Liu, Fuyao, Xie, Rongbin, Zhao, Haitian, Deng, Gang, Chen, Ann T., Gong, Ningbo, Yao, Lei, Zuo, Pengjian, Zhi, Kangkang, Wang, Jiacheng, Gao, Xiaobin, Wang, Jing, Fan, Louzhen, Zhou, Jiangbing

“…Oral drug delivery, which requires surviving the harsh environment in the gastrointestinal (GI) tract and penetrating the intestinal epithelium, has not been…”
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NF-κB pathway inhibitors preferentially inhibit breast cancer stem-like cells by Zhou, Jiangbing, Zhang, Hao, Gu, Peihua, Bai, Jining, Margolick, Joseph B., Zhang, Ying

“…Accumulating evidence indicates that breast cancer is caused by cancer stem cells and cure of breast cancer requires eradication of breast cancer stem cells…”
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Epigenetic regulation of EIF4A1 through DNA methylation and an oncogenic role of eIF4A1 through BRD2 signaling in prostate cancer by Wang, Chao, Leavenworth, Jonathan, Zhang, Chao, Liu, Zhichao, Yuan, Katherine Y., Wang, Yicun, Zhang, Guangxin, Wang, Shuaibin, Cui, Xuelian, Zhang, Yue, Bae, Sejong, Zhou, Jiangbing, Wang, Lizhong, Liu, Runhua

“…In prostate cancers, elongation initiation factor 4A1 (eIF4A1) supports an oncogenic translation program and is highly expressed, but its role remains elusive…”
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Targeted Delivery of Chemo‐Sonodynamic Therapy via Brain Targeting, Glutathione‐Consumable Polymeric Nanoparticles for Effective Brain Cancer Treatment by Wu, Haoan, Gao, Xingchun, Luo, Yuanyuan, Yu, Jiang, Long, Gretchen, Jiang, Zhaozhong, Zhou, Jiangbing

“…Glioblastoma (GBM) is the most aggressive tumor of the central nervous system and remains universally lethal due to lack of effective treatment options and…”
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Topical Capsaicin in Poly(lactic-co-glycolic)acid (PLGA) Nanoparticles Decreases Acute Itch and Heat Pain by Malewicz, Nathalie M, Rattray, Zahra, Oeck, Sebastian, Jung, Sebastian, Escamilla-Rivera, Vicente, Chen, Zeming, Tang, Xiangjun, Zhou, Jiangbing, LaMotte, Robert H

“…Capsaicin, the hot pepper agent, produces burning followed by desensitization. To treat localized itch or pain with minimal burning, low capsaicin…”
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Betulinic acid self-assembled nanoparticles for effective treatment of glioblastoma by Li, Yong, Wang, Yixuan, Gao, Lun, Tan, Yinqiu, Cai, Jiayang, Ye, Zhang, Chen, Ann T, Xu, Yang, Zhao, Linyao, Tong, Shiao, Sun, Qian, Liu, Baohui, Zhang, Shenqi, Tian, Daofeng, Deng, Gang, Zhou, Jiangbing, Chen, Qianxue

“…Glioblastoma (GBM) is the most common and fatal primary tumor in the central nervous system (CNS). Due to the existence of blood-brain barrier (BBB), most…”
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PLEKHA5 regulates tumor growth in metastatic melanoma by Zhang, Hongyi, Zhu, Huifang, Deng, Gang, Zito, Christopher R., Oria, Victor O., Rane, Chetan K., Zhang, Shenqi, Weiss, Sarah A., Tran, Thuy, Adeniran, Adebowale, Zhang, Fanfan, Zhou, Jiangbing, Kluger, Yuval, Bosenberg, Marcus W., Kluger, Harriet M., Jilaveanu, Lucia B.

“…Background PLEKHA5 has previously been identified as a novel molecule implicated in melanoma brain metastasis, a disease that continues to portend a poor…”
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Nanotechnology approaches to drug delivery for the treatment of ischemic stroke by Peng, Bin, Mohammed, Farrah S., Tang, Xiangjun, Liu, Jia, Sheth, Kevin N., Zhou, Jiangbing

“…Ischemic stroke is a major global public health concern that lacks effective treatment options. A significant challenge lies in delivering therapeutic agents…”
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A PILOT STUDY: SPATIOTEMPORALLY-RESOLVED MOLECULAR MECHANISMS OF ACUTE IMMUNE AND NEUROMODULATORY RESPONSES TO TRAUMATIC BRAIN INJURY by Mohammed, Farrah, Mcguone, Declan, Omay, Sacit, Omay, Zeynep Erson, Zhou, Jiangbing

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Brain-targeting, acid-responsive antioxidant nanoparticles for stroke treatment and drug delivery by Zhang, Shenqi, Peng, Bin, Chen, Zeming, Yu, Jiang, Deng, Gang, Bao, Youmei, Ma, Chao, Du, Fengyi, Sheu, Wendy C., Kimberly, W. Taylor, Simard, J. Marc, Coman, Daniel, Chen, Qianxue, Hyder, Fahmeed, Zhou, Jiangbing, Sheth, Kevin N.

“…Stroke is the leading cause of death and disability. Currently, there is no effective pharmacological treatment for this disease, which can be partially…”
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