Search Results - "Zhou, Fuyou"
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A signature of saliva-derived exosomal small RNAs as predicting biomarker for esophageal carcinoma: a multicenter prospective study
Published in Molecular cancer (18-01-2022)“…The tRNA-derived small RNAs (tsRNAs) are produced in a nuclease-dependent manner in responses to variety of stresses that are common in cancers. We focus on a…”
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Repurposing dextromethorphan and metformin for treating nicotine-induced cancer by directly targeting CHRNA7 to inhibit JAK2/STAT3/SOX2 signaling
Published in Oncogene (18-03-2021)“…Smoking is one of the most impactful lifestyle-related risk factors in many cancer types including esophageal squamous cell carcinoma (ESCC). As the major…”
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Fusobacterium nucleatum induces MDSCs enrichment via activation the NLRP3 inflammosome in ESCC cells, leading to cisplatin resistance
Published in Annals of medicine (Helsinki) (31-12-2022)“…To analyse the regulatory effect of Fusobacterium nucleatum (Fn) on NOD-like receptor protein 3 (NLRP3) and myeloid-derived suppressor cells (MDSCs) in…”
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Different frequencies of Porphyromonas gingivalis infection in cancers of the upper digestive tract
Published in Cancer letters (28-09-2017)“…The high incidence rate of multiple carcinomas in the upper digestive tract is often explained in terms of involvement of the same underlying risk factors. It…”
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Clinical impact of Fn-induced high expression of KIR2DL1 in CD8 T lymphocytes in oesophageal squamous cell carcinoma
Published in Annals of medicine (Helsinki) (31-12-2022)“…To analyze the correlation between the inducing effect of Fusobacterium nucleatum (Fn) on the surface expression of the inhibitory receptor KIR2DL1 on CD8 + T…”
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Identification of a DNA methylome profile of esophageal squamous cell carcinoma and potential plasma epigenetic biomarkers for early diagnosis
Published in PloS one (22-07-2014)“…DNA methylation is a critical epigenetic mechanism involved in key cellular processes. Its deregulation has been linked to many human cancers including…”
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Alteration of plasma metabolites associated with chemoradiosensitivity in esophageal squamous cell carcinoma via untargeted metabolomics approach
Published in BMC cancer (02-09-2020)“…To investigate the differences in plasma metabolomic characteristics between pathological complete response (pCR) and non-pCR patients and identify biomarker…”
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Clinical significance and prognostic value of Porphyromonas gingivalis infection in lung cancer
Published in Translational oncology (01-01-2021)“…•P. gingivalis can be colonized in lung cancer tissues.•The microenvironment of cancerous tissues is more conducive to the survival of P. gingivalis than…”
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Identification of crucial long non-coding RNAs and mRNAs along with related regulatory networks through microarray analysis in esophageal carcinoma
Published in Functional & integrative genomics (01-07-2021)“…Esophageal carcinoma (EC) is a tremendous threat to human health and life worldwide. Long non-coding RNAs (lncRNAs) have been identified as crucial players in…”
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Porphyromonas gingivalis promotes malignancy and chemo-resistance via GSK3β-mediated mitochondrial oxidative phosphorylation in human esophageal squamous cell carcinoma
Published in Translational oncology (01-06-2023)“…•GSK3β is a key regulator in the enhancement of the mtOXPHOS induced by Pg in ESCC cells;.•GSK3β is a key regulator in the malignancy and chemo-resistance…”
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KDM4C, a H3K9me3 Histone Demethylase, is Involved in the Maintenance of Human ESCC-Initiating Cells by Epigenetically Enhancing SOX2 Expression
Published in Neoplasia (New York, N.Y.) (01-10-2016)“…Abstract Our studies investigating the existence of tumor-initiating cell (TIC) populations in human esophageal squamous cell carcinoma (ESCC) had identified a…”
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TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis
Published in Cell death discovery (01-12-2023)“…The long non-coding RNA (lncRNA) TMEM44-AS1 is a novel lncRNA whose pro-carcinogenic role in gastric cancer and glioma has been demonstrated. However, its…”
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Postoperative serum squamous cell carcinoma antigen and carcinoembryonic antigen predict overall survival in surgical patients with esophageal squamous cell carcinoma
Published in Frontiers in oncology (22-09-2023)“…Background Tumor markers are routinely used in clinical practice. However, for resectable patients with esophageal squamous cell carcinoma (ESCC), they are…”
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Definition and risk factors of early recurrence based on affecting prognosis of esophageal squamous cell carcinoma patients after radical resection
Published in Translational oncology (01-06-2021)“…•21 months was defined as the optimal threshold of RFS for dividing patients into early and late recurrence according to the influence on OS by minimum P-value…”
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Epigenetic silencing of TMEM176A activates ERK signaling in human hepatocellular carcinoma
Published in Clinical epigenetics (06-11-2018)“…The role of TMEM176A in human hepatocellular carcinoma (HCC) is unknown. This study explored the epigenetic regulation and function of TMEM176A in human HCC…”
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Directional Migration in Esophageal Squamous Cell Carcinoma (ESCC) is Epigenetically Regulated by SET Nuclear Oncogene, a Member of the Inhibitor of Histone Acetyltransferase Complex
Published in Neoplasia (New York, N.Y.) (01-11-2017)“…Directional cell migration is of fundamental importance to a variety of biological events, including metastasis of malignant cells. Herein, we specifically…”
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Methylation of ZNF331 is an independent prognostic marker of colorectal cancer and promotes colorectal cancer growth
Published in Clinical epigenetics (18-10-2017)“…ZNF331 was reported to be a transcriptional repressor. Methylation of the promoter region of ZNF331 has been found frequently in human esophageal and gastric…”
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Notch1 is a 5-fluorouracil resistant and poor survival marker in human esophagus squamous cell carcinomas
Published in PloS one (07-02-2013)“…Notch signaling involves the processes that govern cell proliferation, cell fate decision, cell differentiation and stem cell maintenance. Due to its…”
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Chemoradiation versus oesophagectomy for locally advanced oesophageal cancer in Chinese patients: study protocol for a randomised controlled trial
Published in Current controlled trials in cardiovascular medicine (11-04-2019)“…Surgery is the gold standard treatment for local advanced disease, while definitive concurrent chemoradiotherapy (DCRT) is recommended for those who are…”
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