Search Results - "Zhou, Fulai"

Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin by Yin, Wanchao, Luan, Xiaodong, Li, Zhihai, Zhou, Ziwei, Wang, Qingxing, Gao, Minqi, Wang, Xiaoxi, Zhou, Fulai, Shi, Jingjing, You, Erli, Liu, Mingliang, Wang, Qingxia, Jiang, Yi, Jiang, Hualiang, Xiao, Gengfu, Zhang, Leike, Yu, Xuekui, Zhang, Shuyang, Eric Xu, H.

“…The COVID-19 pandemic caused by nonstop infections of SARS-CoV-2 has continued to ravage many countries worldwide. Here we report that suramin, a 100-year-old…”
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Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir by Yin, Wanchao, Mao, Chunyou, Luan, Xiaodong, Shen, Dan-Dan, Shen, Qingya, Su, Haixia, Wang, Xiaoxi, Zhou, Fulai, Zhao, Wenfeng, Gao, Minqi, Chang, Shenghai, Xie, Yuan-Chao, Tian, Guanghui, Jiang, He-Wei, Tao, Sheng-Ce, Shen, Jingshan, Jiang, Yi, Jiang, Hualiang, Xu, Yechun, Zhang, Shuyang, Zhang, Yan, Xu, H Eric

“…The pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global crisis…”
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Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor by Liu, Qiufeng, Yang, Dehua, Zhuang, Youwen, Croll, Tristan I., Cai, Xiaoqing, Dai, Antao, He, Xinheng, Duan, Jia, Yin, Wanchao, Ye, Chenyu, Zhou, Fulai, Wu, Beili, Zhao, Qiang, Xu, H. Eric, Wang, Ming-Wei, Jiang, Yi

“…Cholecystokinin A receptor (CCK A R) belongs to family A G-protein-coupled receptors and regulates nutrient homeostasis upon stimulation by cholecystokinin…”
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Genome-wide identification and evolutionary analysis of leucine-rich repeat receptor-like protein kinase genes in soybean by Zhou, Fulai, Guo, Yong, Qiu, Li-Juan

“…Leucine-rich repeat receptor-like kinases (LRR-RLKs) constitute the largest subfamily of receptor-like kinases in plant. A number of reports have demonstrated…”
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Structural mechanism of calcium-mediated hormone recognition and Gβ interaction by the human melanocortin-1 receptor by Ma, Shanshan, Chen, Yan, Dai, Antao, Yin, Wanchao, Guo, Jia, Yang, Dehua, Zhou, Fulai, Jiang, Yi, Wang, Ming-Wei, Xu, H. Eric

“…Melanocortins are peptide hormones critical for the regulation of stress response, energy homeostasis, inflammation, and skin pigmentation. Their functions are…”
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Molecular basis for kinin selectivity and activation of the human bradykinin receptors by Yin, Yu-Ling, Ye, Chenyu, Zhou, Fulai, Wang, Jia, Yang, Dehua, Yin, Wanchao, Wang, Ming-Wei, Xu, H. Eric, Jiang, Yi

“…Bradykinin and kallidin are endogenous kinin peptide hormones that belong to the kallikrein–kinin system and are essential to the regulation of blood pressure,…”
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Structural basis for the tethered peptide activation of adhesion GPCRs by Ping, Yu-Qi, Xiao, Peng, Yang, Fan, Zhao, Ru-Jia, Guo, Sheng-Chao, Yan, Xu, Wu, Xiang, Zhang, Chao, Lu, Yan, Zhao, Fenghui, Zhou, Fulai, Xi, Yue-Tong, Yin, Wanchao, Liu, Feng-Zhen, He, Dong-Fang, Zhang, Dao-Lai, Zhu, Zhong-Liang, Jiang, Yi, Du, Lutao, Feng, Shi-Qing, Schöneberg, Torsten, Liebscher, Ines, Xu, H. Eric, Sun, Jin-Peng

“…Adhesion G-protein-coupled receptors (aGPCRs) are important for organogenesis, neurodevelopment, reproduction and other processes 1 – 6 . Many aGPCRs are…”
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Molecular basis of ligand recognition and activation of human V2 vasopressin receptor by Zhou, Fulai, Ye, Chenyu, Ma, Xiaomin, Yin, Wanchao, Croll, Tristan I., Zhou, Qingtong, He, Xinheng, Zhang, Xiaokang, Yang, Dehua, Wang, Peiyi, Xu, H. Eric, Wang, Ming-Wei, Jiang, Yi

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Structural basis for activation of the growth hormone-releasing hormone receptor by Zhou, Fulai, Zhang, Huibing, Cong, Zhaotong, Zhao, Li-Hua, Zhou, Qingtong, Mao, Chunyou, Cheng, Xi, Shen, Dan-Dan, Cai, Xiaoqing, Ma, Cheng, Wang, Yuzhe, Dai, Antao, Zhou, Yan, Sun, Wen, Zhao, Fenghui, Zhao, Suwen, Jiang, Hualiang, Jiang, Yi, Yang, Dehua, Eric Xu, H., Zhang, Yan, Wang, Ming-Wei

“…Growth hormone-releasing hormone (GHRH) regulates the secretion of growth hormone that virtually controls metabolism and growth of every tissue through its…”
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A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor by Sun, Wen, Chen, Li-Nan, Zhou, Qingtong, Zhao, Li-Hua, Yang, Dehua, Zhang, Huibing, Cong, Zhaotong, Shen, Dan-Dan, Zhao, Fenghui, Zhou, Fulai, Cai, Xiaoqing, Chen, Yan, Zhou, Yan, Gadgaard, Sarina, van der Velden, Wijnand J. C., Zhao, Suwen, Jiang, Yi, Rosenkilde, Mette M., Xu, H. Eric, Zhang, Yan, Wang, Ming-Wei

“…Glucagon-like peptides (GLP-1 and GLP-2) are two proglucagon-derived intestinal hormones that mediate distinct physiological functions through two related…”
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Constitutive signal bias mediated by the human GHRHR splice variant 1 by Cong, Zhaotong, Zhou, Fulai, Zhang, Chao, Zou, Xinyu, Zhang, Huibing, Wang, Yuzhe, Zhou, Qingtong, Cai, Xiaoqing, Liu, Qiaofeng, Li, Jie, Shao, Lijun, Mao, Chunyou, Wang, Xi, Wu, Jihong, Xia, Tian, Zhao, Li-Hua, Jiang, Hualiang, Zhang, Yan, Xu, H. Eric, Cheng, Xi, Yang, Dehua, Wang, Ming-Wei

“…Alternative splicing of G protein–coupled receptors has been observed, but their functions are largely unknown. Here, we report that a splice variant (SV1) of…”
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Structural insights into the ligand binding and Gi coupling of serotonin receptor 5-HT5A by Tan, Yangxia, Xu, Peiyu, Huang, Sijie, Yang, Gong, Zhou, Fulai, He, Xinheng, Ma, Honglei, Xu, H. Eric, Jiang, Yi

“…5-hydroxytryptamine receptor 5A (5-HT 5A ) belongs to the 5-HT receptor family and signals through the G i/o protein. It is involved in nervous system…”
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Application of chemical biology in target identification and drug discovery by Zhu, Yue, Xiao, Ting, Lei, Saifei, Zhou, Fulai, Wang, Ming-Wei

“…Drug discovery and development is vital to the well-being of mankind and sustainability of the pharmaceutical industry. Using chemical biology approaches to…”
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Removal of ammonia nitrogen from black and odorous water by macrophytes based on laboratory microcosm experiments by Huangfu, Shangmin, Zhou, Fulai, Zheng, Xianyun, Zhang, Xiaoping, Hu, Lifang

“…In recent years, the removal mechanism of ammonia nitrogen in black and odorous water (BOW), especially in the process of phytoremediation, has been a research…”
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A Novel Dual-Fc Bispecific Antibody with Enhanced Fc Effector Function by Zhou, Fulai, Ben, Yinyin, Jiang, Hao, Tan, Siwen, Mu, Guangmao, Zha, Zhengxia, Dong, Shuting, Huang, Sheng, Zhou, Yijun, Jin, Ying, Chiu, Mark L.

“…Bispecific antibodies (BsAbs) are undergoing continued development for applications in oncology and autoimmune diseases. While increasing activity by having…”
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Distinct molecular profiles drive multifaceted characteristics of colorectal cancer metastatic seeds by Zhao, Yuanyuan, Zhang, Bing, Ma, Yiming, Guo, Mengmeng, Zhao, Fuqiang, Chen, Jianan, Wang, Bingzhi, Jin, Hua, Zhou, Fulai, Guan, Jiawei, Zhao, Qian, Liu, Qian, Wang, Hongying, Zhao, Fangqing, Wang, Xia

“…Metastasis of primary tumors remains a challenge for early diagnosis and prevention. The cellular properties and molecular drivers of metastatically competent…”
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Gene-based SNP identification and validation in soybean using next-generation transcriptome sequencing by Guo, Yong, Su, Bohong, Tang, Junyong, Zhou, Fulai, Qiu, Li-Juan

“…Gene-based molecular markers are increasingly used in crop breeding programs for marker-assisted selection. However, identification of genetic variants…”
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Colorectal Cancer Patient‐Derived 2D and 3D Models Efficiently Recapitulate Inter‐ and Intratumoral Heterogeneity by Zhao, Yuanyuan, Zhang, Bing, Ma, Yiming, Zhao, Fuqiang, Chen, Jianan, Wang, Bingzhi, Jin, Hua, Zhou, Fulai, Guan, Jiawei, Zhao, Qian, Wang, Hongying, Liu, Qian, Zhao, Fangqing, Wang, Xia

“…Pre‐existing drug resistance and tumorigenicity of cancer cells are highly correlated with therapeutic failure and tumor growth. However, current cancer models…”
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Structural insights into the ligand binding and G i coupling of serotonin receptor 5-HT 5A by Tan, Yangxia, Xu, Peiyu, Huang, Sijie, Yang, Gong, Zhou, Fulai, He, Xinheng, Ma, Honglei, Xu, H Eric, Jiang, Yi

“…5-hydroxytryptamine receptor 5A (5-HT ) belongs to the 5-HT receptor family and signals through the G protein. It is involved in nervous system regulation and…”
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Development and utilization of a new chemically-induced soybean library with a high mutation density by Li, Zhongfeng, Jiang, Lingxue, Ma, Yansong, Wei, Zhongyan, Hong, Huilong, Liu, Zhangxiong, Lei, Jinhui, Liu, Ying, Guan, Rongxia, Guo, Yong, Jin, Longguo, Zhang, Lijuan, Li, Yinghui, Ren, Yulong, He, Wei, Liu, Ming, Htwe, Nang Myint Phyu Sin, Liu, Lin, Guo, Bingfu, Song, Jian, Tan, Bing, Liu, Guifeng, Li, Maiquan, Zhang, Xianli, Liu, Bo, Shi, Xuehui, Han, Sining, Hua, Sunan, Zhou, Fulai, Yu, Lili, Li, Yanfei, Wang, Shuang, Wang, Jun, Chang, Ruzhen, Qiu, Lijuan

“…Mutagenized populations have provided important materials for introducing variation and identifying gene function in plants. In this study, an ethyl…”
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