Search Results - "Zhou, Felix"

Diverse and robust molecular algorithms using reprogrammable DNA self-assembly by Woods, Damien, Doty, David, Myhrvold, Cameron, Hui, Joy, Zhou, Felix, Yin, Peng, Winfree, Erik

“…Molecular biology provides an inspiring proof-of-principle that chemical systems can store and process information to direct molecular activities such as the…”
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Blebs promote cell survival by assembling oncogenic signalling hubs by Weems, Andrew D., Welf, Erik S., Driscoll, Meghan K., Zhou, Felix Y., Mazloom-Farsibaf, Hanieh, Chang, Bo-Jui, Murali, Vasanth S., Gihana, Gabriel M., Weiss, Byron G., Chi, Joseph, Rajendran, Divya, Dean, Kevin M., Fiolka, Reto, Danuser, Gaudenz

“…Most human cells require anchorage for survival. Cell–substrate adhesion activates diverse signalling pathways, without which cells undergo anoikis—a form of…”
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Loop extrusion as a mechanism for formation of DNA damage repair foci by Arnould, Coline, Rocher, Vincent, Finoux, Anne-Laure, Clouaire, Thomas, Li, Kevin, Zhou, Felix, Caron, Pierre, Mangeot, Philippe. E., Ricci, Emiliano P., Mourad, Raphaël, Haber, James E., Noordermeer, Daan, Legube, Gaëlle

“…The repair of DNA double-strand breaks (DSBs) is essential for safeguarding genome integrity. When a DSB forms, the PI3K-related ATM kinase rapidly triggers…”
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A deep learning framework for quality assessment and restoration in video endoscopy by Ali, Sharib, Zhou, Felix, Bailey, Adam, Braden, Barbara, East, James E., Lu, Xin, Rittscher, Jens

“…•Accurate real-time detection and localisation of artifacts in endoscopy videos.•A novel video quality assessment metric based on type, location and area of…”
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Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones by Chauveau, Anne, Pirgova, Gabriela, Cheng, Hung-Wei, De Martin, Angelina, Zhou, Felix Y., Wideman, Sarah, Rittscher, Jens, Ludewig, Burkhard, Arnon, Tal I.

“…Lymphocyte homeostasis and immune surveillance require that T and B cells continuously recirculate between secondary lymphoid organs. Here, we used intravital…”
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Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly by Wong, Siu‐Shing, Wilmott, Zachary M, Saurya, Saroj, Alvarez‐Rodrigo, Ines, Zhou, Felix Y, Chau, Kwai‐Yin, Goriely, Alain, Raff, Jordan W

“…Mitotic centrosomes are formed when centrioles start to recruit large amounts of pericentriolar material (PCM) around themselves in preparation for mitosis…”
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Human ZBP1 induces cell death‐independent inflammatory signaling via RIPK3 and RIPK1 by Peng, Ruoshi, Wang, Chris Kedong, Wang‐Kan, Xuan, Idorn, Manja, Kjær, Majken, Zhou, Felix Y, Fiil, Berthe Katrine, Timmermann, Frederik, Orozco, Susana L, McCarthy, Julia, Leung, Carol S, Lu, Xin, Bagola, Katrin, Rehwinkel, Jan, Oberst, Andrew, Maelfait, Jonathan, Paludan, Søren R, Gyrd‐Hansen, Mads

“…ZBP1 is an interferon‐induced cytosolic nucleic acid sensor that facilitates antiviral responses via RIPK3. Although ZBP1‐mediated programmed cell death is…”
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β-Carotene conversion to vitamin A delays atherosclerosis progression by decreasing hepatic lipid secretion in mice by Zhou, Felix, Wu, Xiaoyun, Pinos, Ivan, Abraham, Benjamin M., Barrett, Tessa J., von Lintig, Johannes, Fisher, Edward A., Amengual, Jaume

“…Atherosclerosis is characterized by the pathological accumulation of cholesterol-laden macrophages in the arterial wall. Atherosclerosis is also the main…”
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An Autonomous Oscillation Times and Executes Centriole Biogenesis by Aydogan, Mustafa G., Steinacker, Thomas L., Mofatteh, Mohammad, Wilmott, Zachary M., Zhou, Felix Y., Gartenmann, Lisa, Wainman, Alan, Saurya, Saroj, Novak, Zsofia A., Wong, Siu-Shing, Goriely, Alain, Boemo, Michael A., Raff, Jordan W.

“…The accurate timing and execution of organelle biogenesis is crucial for cell physiology. Centriole biogenesis is regulated by Polo-like kinase 4 (Plk4) and…”
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Projective light-sheet microscopy with flexible parameter selection by Chen, Bingying, Chang, Bo-Jui, Daetwyler, Stephan, Zhou, Felix, Sharma, Shiv, Lee, Donghoon M., Nayak, Amruta, Noh, Jungsik, Dubrovinski, Konstantin, Chen, Elizabeth H., Glotzer, Michael, Fiolka, Reto

“…Projection imaging accelerates volumetric interrogation in fluorescence microscopy, but for multi-cellular samples, the resulting images may lack contrast, as…”
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Enhanced CHOLESTEROL biosynthesis promotes breast cancer metastasis via modulating CCDC25 expression and neutrophil extracellular traps formation by Tang, Qiqi, Liang, Beibei, Zhang, Lisha, Li, Xuhui, Li, Hengyu, Jing, Wei, Jiang, Yingjie, Zhou, Felix, Zhang, Jian, Meng, Yanchun, Yang, Xinhua, Yang, Hao, Huang, Gang, Zhao, Jian

“…Neutrophil extracellular traps (NETs) has been demonstrated to regulate the metastasis of breast cancer. In this study, we showed that de novo cholesterol…”
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Deposition of 5-Methylcytosine on Enhancer RNAs Enables the Coactivator Function of PGC-1α by Aguilo, Francesca, Li, SiDe, Balasubramaniyan, Natarajan, Sancho, Ana, Benko, Sabina, Zhang, Fan, Vashisht, Ajay, Rengasamy, Madhumitha, Andino, Blanca, Chen, Chih-hung, Zhou, Felix, Qian, Chengmin, Zhou, Ming-Ming, Wohlschlegel, James A., Zhang, Weijia, Suchy, Frederick J., Walsh, Martin J.

“…The Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1α) is a transcriptional co-activator that plays a central role in adapted…”
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Centriole distal-end proteins CP110 and Cep97 influence centriole cartwheel growth at the proximal-end by Aydogan, Mustafa G, Hankins, Laura E, Steinacker, Thomas L, Mofatteh, Mohammad, Saurya, Saroj, Wainman, Alan, Wong, Siu-Shing, Lu, Xin, Zhou, Felix Y, Raff, Jordan W

“…Centrioles are composed of a central cartwheel tethered to nine-fold symmetric microtubule (MT) blades. The centriole cartwheel and MTs are thought to grow…”
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Live cell monitoring of double strand breaks in S. cerevisiae by Waterman, David P, Zhou, Felix, Li, Kevin, Lee, Cheng-Sheng, Tsabar, Michael, Eapen, Vinay V, Mazzella, Allison, Haber, James E

“…We have used two different live-cell fluorescent protein markers to monitor the formation and localization of double-strand breaks (DSBs) in budding yeast…”
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A wild-type mouse-based model for the regression of inflammation in atherosclerosis by Peled, Michael, Nishi, Hitoo, Weinstock, Ada, Barrett, Tessa J, Zhou, Felix, Quezada, Alexandra, Fisher, Edward A

“…Atherosclerosis can be induced by the injection of a gain-of-function mutant of proprotein convertase subtilisin/kexin type 9 (PCSK9)-encoding adeno-associated…”
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ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis by Royer, Christophe, Sandham, Elizabeth, Slee, Elizabeth, Schneider, Falk, Lagerholm, Christoffer B., Godwin, Jonathan, Veits, Nisha, Hathrell, Holly, Zhou, Felix, Leonavicius, Karolis, Garratt, Jemma, Narendra, Tanaya, Vincent, Anna, Jones, Celine, Child, Tim, Coward, Kevin, Graham, Chris, Fritzsche, Marco, Lu, Xin, Srinivas, Shankar

“…During development, pseudostratified epithelia undergo large scale morphogenetic events associated with increased mechanical stress. Using a variety of genetic…”
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Increasing the field-of-view in oblique plane microscopy via optical tiling by Chen, Bingying, Chang, Bo-Jui, Zhou, Felix Y, Daetwyler, Stephan, Sapoznik, Etai, Nanes, Benjamin A, Terrazas, Isabella, Gihana, Gabriel M, Castro, Lizbeth Perez, Chan, Isaac S, Conacci-Sorrell, Maralice, Dean, Kevin M, Millett-Sikking, Alfred, York, Andrew G, Fiolka, Reto

“…Fast volumetric imaging of large fluorescent samples with high-resolution is required for many biological applications. Oblique plane microscopy (OPM) provides…”
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Cell autonomous role of iASPP deficiency in causing cardiocutaneous disorders by Dedeić, Zinaida, Sutendra, Gopinath, Hu, Ying, Chung, Kathryn, Slee, Elizabeth A., White, Michael J., Zhou, Felix Y., Goldin, Robert D., Ferguson, David J. P., McAndrew, Debra, Schneider, Jurgen E., Lu, Xin

“…Desmosome components are frequently mutated in cardiac and cutaneous disorders in animals and humans and enhanced inflammation is a common feature of these…”
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Motion sensing superpixels (MOSES) is a systematic computational framework to quantify and discover cellular motion phenotypes by Zhou, Felix Y, Ruiz-Puig, Carlos, Owen, Richard P, White, Michael J, Rittscher, Jens, Lu, Xin

“…Correct cell/cell interactions and motion dynamics are fundamental in tissue homeostasis, and defects in these cellular processes cause diseases. Therefore,…”
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Characterization of Biological Motion Using Motion Sensing Superpixels by Zhou, Felix Y, Ruiz-Puig, Carlos, Owen, Richard P, White, Michael J, Rittscher, Jens, Lu, Xin

“…Precise spatiotemporal regulation is the foundation for the healthy development and maintenance of living organisms. All cells must correctly execute their…”
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