Search Results - "Zhou, Fankun"

Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures by Zhou, Fankun, Yin, Guangming, Gao, Yanyan, Liu, Dong, Xie, Jie, Ouyang, Lu, Fan, Ying, Yu, Han, Zha, Zhipeng, Wang, Kai, Shao, Lijian, Feng, Chang, Fan, Guangqin

“…•Early effects of Pb, Cd, and Hg mixtures were evaluated at low levels.•Metal mixtures (MM) caused multiple organ changes in morphology and function.•MM…”
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Interplay and long-lasting effects of maternal low-level Pb, Hg, and Cd exposures on offspring cognition by Ouyang, Lu, Li, Qi, Yang, Shuo, Yan, Lingyu, Li, Jiajun, Wan, Xin, Cheng, Hui, Li, Lingling, Liu, Peishan, Xie, Jie, Du, Guihua, Zhou, Fankun, Feng, Chang, Fan, Guangqin

“…Lead (Pb), mercury (Hg), and cadmium (Cd) are prevalent and persistent environmental contaminants, causing detrimental effects on millions of individuals…”
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Dietary, Nutrient Patterns and Blood Essential Elements in Chinese Children with ADHD by Zhou, Fankun, Wu, Fengyun, Zou, Shipu, Chen, Ying, Feng, Chang, Fan, Guangqin

“…Dietary or nutrient patterns represent the combined effects of foods or nutrients, and elucidate efficaciously the impact of diet on diseases. Because the…”
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Co-exposure to low-dose lead, cadmium, and mercury promotes memory deficits in rats: Insights from the dynamics of dendritic spine pruning in brain development by Zhou, Fankun, Ouyang, Lu, Xie, Jie, Liu, Sisi, Li, Qi, Yang, Shuo, Li, Jiajun, Su, Rui, Rao, Shaoqi, Yan, Lingyu, Wan, Xin, Cheng, Hui, Liu, Peishan, Li, Lingling, Zhu, Yanhui, Du, Guihua, Feng, Chang, Fan, Guangqin

“…Lead (Pb), cadmium (Cd), and mercury (Hg) are environmentally toxic heavy metals that can be simultaneously detected at low levels in the blood of the general…”
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dbMDEGA: a database for meta-analysis of differentially expressed genes in autism spectrum disorder by Zhang, Shuyun, Deng, Libin, Jia, Qiyue, Huang, Shaoting, Gu, Junwang, Zhou, Fankun, Gao, Meng, Sun, Xinyi, Feng, Chang, Fan, Guangqin

“…Autism spectrum disorders (ASD) are hereditary, heterogeneous and biologically complex neurodevelopmental disorders. Individual studies on gene expression in…”
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The effect of the hemochromatosis (HFE) genotype on lead load and iron metabolism among lead smelter workers by Fan, Guangqin, Du, Guihua, Li, Huijun, Lin, Fen, Sun, Ziyong, Yang, Wei, Feng, Chang, Zhu, Gaochun, Li, Yanshu, Chen, Ying, Jiao, Huan, Zhou, Fankun

“…Both an excess of toxic lead (Pb) and an essential iron disorder have been implicated in many diseases and public health problems. Iron metabolism genes, such…”
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Lead-induced ER calcium release and inhibitory effects of methionine choline in cultured rat hippocampal neurons by Fan, Guangqin, Zhou, Fankun, Feng, Chang, Wu, Fengyun, Ye, Weiwei, Wang, Chunhong, Lin, Fen, Yan, Ji, Li, Yanshu, Chen, Ying, Bi, Yongyi

“…► The effects of Pb2+ on [Ca2+]i in cultured rat hippocampal neurons are examined. ► The antagonistic effects of methionine choline are investigated. ► Pb2+…”
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The association between prenatal cadmium exposure and birth weight: A systematic review and meta-analysis of available evidence by Huang, Shouhe, Kuang, Jie, Zhou, Fankun, Jia, Qiyue, Lu, Qi, Feng, Chang, Yang, Wei, Fan, Guangqin

“…We conducted a meta-analysis to evaluate the association between prenatal cadmium (Cd) exposure and birth weight. PubMed, Embase, China National Knowledge…”
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Cognitive outcomes caused by low-level lead, cadmium, and mercury mixture exposure at distinct phases of brain development by Ouyang, Lu, Li, Qi, Rao, Shaoqi, Su, Rui, Zhu, Yanhui, Du, Guihua, Xie, Jie, Zhou, Fankun, Feng, Chang, Fan, Guangqin

“…Contaminated water and food are the main sources of lead, cadmium, and mercury in the human body. Long-term and low-level ingestion of these toxic heavy metals…”
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Insights into cognitive deficits caused by low-dose toxic heavy metal mixtures and their remediation through a postnatal enriched environment in rats by Zhou, Fankun, Yin, Guangming, Gao, Yanyan, Ouyang, Lu, Liu, Sisi, Jia, Qiyue, Yu, Han, Zha, Zhipeng, Wang, Kai, Xie, Jie, Fan, Ying, Shao, Lijian, Feng, Chang, Fan, Guangqin

“…[Display omitted] •Metal mixtures (MM) caused cognitive deficits at human environmental exposure related levels.•MM induced cognitive deficits may be related…”
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Combined exposure of low dose lead, cadmium, arsenic, and mercury in mice by Zhou, Fankun, Feng, Chang, Fan, Guangqin

“…•The study by Cobbina et al. published in Chemosphere in 2015 deserve critiques.•Levels of toxic metals measured in the control mice are extremely…”
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Toxic effects of combined exposure to four heavy metals at low doses by Fan, Guangqin, Zhou, Fankun, Feng, Chang

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RyRs mediate lead-induced neurodegenerative disorders through calcium signaling pathways by Zhou, Fankun, Du, Guihua, Xie, Jie, Gu, Junwang, Jia, Qiyue, Fan, Ying, Yu, Han, Zha, Zhipeng, Wang, Kai, Ouyang, Lu, Shao, Lijian, Feng, Chang, Fan, Guangqin

“…[Display omitted] •Regulation of RyRs upon Pb exposure were studied in animal, tissue and cell models.•RyRs upregulation mediated Pb-induced neurodegenerative…”
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Lead, cadmium, arsenic, and mercury combined exposure disrupted synaptic homeostasis through activating the Snk-SPAR pathway by Zhou, Fankun, Xie, Jie, Zhang, Shuyun, Yin, Guangming, Gao, Yanyan, Zhang, Yuanyuan, Bo, Dandan, Li, Zongguang, Liu, Sisi, Feng, Chang, Fan, Guangqin

“…Lead (Pb), cadmium (Cd), arsenic (As), and mercury (Hg) are among the leading toxic agents detected in the environment, and they have also been detected…”
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Insight into the effect of a heavy metal mixture on neurological damage in rats through combined serum metabolomic and brain proteomic analyses by Xie, Jie, Zhou, Fankun, Ouyang, Lu, Li, Qi, Rao, Shaoqi, Su, Rui, Yang, Shuo, Li, Jiajun, Wan, Xin, Yan, Lingyu, Liu, Peishan, Cheng, Hui, Li, Lingling, Du, Guihua, Feng, Chang, Fan, Guangqin

“…The heavy metals lead (Pb), cadmium (Cd), and mercury (Hg) that cause neurocognitive impairment have been extensively studied. These elements typically do not…”
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Oxidative stress in the neurodegenerative brain following lifetime exposure to lead in rats: Changes in lifespan profiles by Feng, Chang, Liu, Sisi, Zhou, Fankun, Gao, Yanyan, Li, Yanshu, Du, Guihua, Chen, Ying, Jiao, Huan, Feng, Jiangao, Zhang, Yuanyuan, Bo, Dandan, Li, Zongguang, Fan, Guangqin

“…•Rats were exposed to Pb throughout their lifetime from the embryonic stage to old age.•Changes in lifespan profiles of Pb-induced neurodegeneration in rats…”
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Hippocampal LIMK1-mediated Structural Synaptic Plasticity in Neurobehavioral Deficits Induced by a Low-dose Heavy Metal Mixture by Zhou, Fankun, Ouyang, Lu, Li, Qi, Yang, Shuo, Liu, Sisi, Yu, Han, Jia, Qiyue, Rao, Shaoqi, Xie, Jie, Du, Guihua, Feng, Chang, Fan, Guangqin

“…Humans are commonly exposed to the representative neurotoxic heavy metals lead (Pb), cadmium (Cd), and mercury (Hg). These three substances can be detected…”
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Pregnancy and lactation mixed exposure to lead, cadmium, and mercury alters maternal-offspring single heavy metal load: A factorial design by Du, Guihua, Zhou, Fankun, Ouyang, Lu, Wang, Kai, Rao, Shaoqi, Su, Rui, Zhu, Yanhui, Guo, Kechu, Xiao, Jinmei, Xie, Jie, Li, Qi, Feng, Chang, Fan, Guangqin

“…Environmental exposure to heavy metal mixture of lead (Pb), cadmium (Cd), and mercury (Hg) would induce hazardous health effects. However, there is a paucity…”
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Analysis of search strategies for evaluating low-dose heavy metal mixture induced cognitive deficits in rats: An early sensitive toxicological approach by Jia, Qiyue, Zhang, Yuanyuan, Liu, Sisi, Li, Zongguang, Zhou, Fankun, Shao, Lijian, Feng, Chang, Fan, Guangqin

“…Heavy metals such as lead (Pb), cadmium (Cd), and mercury (Hg) are representative neurotoxicological contaminants that can evoke cognitive dysfunctions. Low…”
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Association between multiple metal(loid)s exposure and renal function: a cross-sectional study from southeastern China by Du, Guihua, Song, Xiaoguang, Zhou, Fankun, Ouyang, Lu, Li, Qi, Ruan, Shiying, Yang, Shuo, Rao, Shaoqi, Wan, Xin, Xie, Jie, Feng, Chang, Fan, Guangqin

“…In the real world, humans are exposed to multiple metal(loid)s (designated hereafter metals) that contain essential metals as well as toxic metals. Exposure to…”
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