Search Results - "Zhou, Enhua H."

Cell volume change through water efflux impacts cell stiffness and stem cell fate by Guo, Ming, Pegoraro, Adrian F., Mao, Angelo, Zhou, Enhua H., Arany, Praveen R., Han, Yulong, Burnette, Dylan T., Jensen, Mikkel H., Kasza, Karen E., Moore, Jeffrey R., Mackintosh, Frederick C., Fredberg, Jeffrey J., Mooney, David J., Lippincott-Schwartz, Jennifer, Weitz, David A.

“…Cells alter their mechanical properties in response to their local microenvironment; this plays a role in determining cell function and can even influence stem…”
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Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction by Stamer, W. Daniel, Braakman, Sietse T., Zhou, Enhua H., Ethier, C. Ross, Fredberg, Jeffrey J., Overby, Darryl R., Johnson, Mark

“…Ocular hypertension in glaucoma develops due to age-related cellular dysfunction in the conventional outflow tract, resulting in increased resistance to…”
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Propulsion and navigation within the advancing monolayer sheet by Kim, Jae Hun, Serra-Picamal, Xavier, Tambe, Dhananjay T., Zhou, Enhua H., Park, Chan Young, Sadati, Monirosadat, Park, Jin-Ah, Krishnan, Ramaswamy, Gweon, Bomi, Millet, Emil, Butler, James P., Trepat, Xavier, Fredberg, Jeffrey J.

“…As a wound heals, or a body plan forms, or a tumour invades, observed cellular motions within the advancing cell swarm are thought to stem from yet to be…”
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Altered mechanobiology of Schlemm’s canal endothelial cells in glaucoma by Overby, Darryl R., Zhou, Enhua H., Vargas-Pinto, Rocio, Pedrigi, Ryan M., Fuchshofer, Rudolf, Braakman, Sietse T., Gupta, Ritika, Perkumas, Kristin M., Sherwood, Joseph M., Vahabikashi, Amir, Dang, Quynh, Kim, Jae Hun, Ethier, C. Ross, Stamer, W. Daniel, Fredberg, Jeffrey J., Johnson, Mark

“…Increased flow resistance is responsible for the elevated intraocular pressure characteristic of glaucoma, but the cause of this resistance increase is not…”
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Collective cell guidance by cooperative intercellular forces by Tambe, Dhananjay T., Corey Hardin, C., Angelini, Thomas E., Rajendran, Kavitha, Park, Chan Young, Serra-Picamal, Xavier, Zhou, Enhua H., Zaman, Muhammad H., Butler, James P., Weitz, David A., Fredberg, Jeffrey J., Trepat, Xavier

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High-throughput screening for modulators of cellular contractile force by Park, Chan Young, Zhou, Enhua H, Tambe, Dhananjay, Chen, Bohao, Lavoie, Tera, Dowell, Maria, Simeonov, Anton, Maloney, David J, Marinkovic, Aleksandar, Tschumperlin, Daniel J, Burger, Stephanie, Frykenberg, Matthew, Butler, James P, Stamer, W Daniel, Johnson, Mark, Solway, Julian, Fredberg, Jeffrey J, Krishnan, Ramaswamy

“…When cellular contractile forces are central to pathophysiology, these forces comprise a logical target of therapy. Nevertheless, existing high-throughput…”
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Variation of mechanical properties and quantitative proteomics of VSMC along the arterial tree by Dinardo, Carla Luana, Venturini, Gabriela, Zhou, Enhua H, Watanabe, Ii Sei, Campos, Luciene Cristina Gastalho, Dariolli, Rafael, da Motta-Leal-Filho, Joaquim Maurício, Carvalho, Valdemir Melechco, Cardozo, Karina Helena Morais, Krieger, José Eduardo, Alencar, Adriano Mesquita, Pereira, Alexandre Costa

“…Vascular smooth muscle cells (VSMCs) are thought to assume a quiescent and homogeneous mechanical behavior after arterial tree development phase. However,…”
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Hypercompliant Apical Membranes of Bladder Umbrella Cells by Mathai, John C., Zhou, Enhua H., Yu, Weiqun, Kim, Jae Hun, Zhou, Ge, Liao, Yi, Sun, Tung-Tien, Fredberg, Jeffrey J., Zeidel, Mark L.

“…Urinary bladder undergoes dramatic volume changes during filling and voiding cycles. In the bladder the luminal surface of terminally differentiated urothelial…”
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Collective cell guidance by cooperative intercellular forces by Tambe, Dhananjay T., Corey Hardin, C., Angelini, Thomas E., Rajendran, Kavitha, Park, Chan Young, Serra-Picamal, Xavier, Zhou, Enhua H., Zaman, Muhammad H., Butler, James P., Weitz, David A., Fredberg, Jeffrey J., Trepat, Xavier

“…Cells comprising a tissue migrate as part of a collective. How collective processes are coordinated over large multi-cellular assemblies has remained unclear,…”
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Illuminating human health through cell mechanics by Steward, Jr, Robert L, Rosner, Sonia R, Zhou, Enhua H, Fredberg, Jeffrey J

“…Cells reside in mechanically rich and dynamic microenvironments, and the complex interplay between mechanics and biology is widely acknowledged. Recent…”
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Cell rheology: mush rather than machine by Zhou, Enhua H, Martinez, Fernando D, Fredberg, Jeffrey J

“…The cytoplasm of living cells responds to deformation in much the same way as a water-filled sponge does. This behaviour, although intuitive, is connected to…”
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A Compact Whole-Eye Perfusion System to Evaluate Pharmacologic Responses of Outflow Facility by Zhou, Enhua H, Paolucci, Michael, Dryja, Thaddeus P, Manley, Ted, Xiang, Chuanxi, Rice, Dennis S, Prasanna, Ganesh, Chen, Amy

“…To discover novel therapies that lower IOP by increasing aqueous humor outflow facility, ex vivo ocular perfusion systems provide a valuable tool. However,…”
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Multiscale Measurements of the Mechanical Properties of Collagen Matrix by Li, Haiyue, Xu, Bin, Zhou, Enhua H, Sunyer, Raimon, Zhang, Yanhang

“…The underlying mechanisms by which extracellular matrix (ECM) mechanics influences cell and tissue function remain to be elucidated because the events…”
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Assessing the impact of engineered nanoparticles on wound healing using a novel in vitro bioassay by Zhou, Enhua H, Watson, Christa, Pizzo, Richard, Cohen, Joel, Dang, Quynh, Ferreira de Barros, Pedro Macul, Park, Chan Young, Chen, Cheng, Brain, Joseph D, Butler, James P, Ruberti, Jeffrey W, Fredberg, Jeffrey J, Demokritou, Philip

“…As engineered nanoparticles (ENPs) increasingly enter consumer products, humans become increasingly exposed. The first line of defense against ENPs is the…”
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Vascular smooth muscle cells exhibit a progressive loss of rigidity with serial culture passaging by Dinardo, Carla Luana, Venturini, Gabriela, Omae, Samantha Vieira, Zhou, Enhua H, da Motta-Leal-Filho, Joaquim Maurício, Dariolli, Rafael, Krieger, José Eduardo, Alencar, Adriano Mesquita, Costa Pereira, Alexandre

“…One drawback of in vitro cell culturing is the dedifferentiation process that cells experience. Smooth muscle cells (SMC) also change molecularly and…”
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Mush rather than machine by Zhou, Enhua H., Martinez, Fernando D., Fredberg, Jeffrey J.

“…The cytoplasm of living cells responds to deformation in much the same way as a water-filled sponge does. This behaviour, although intuitive, is connected to…”
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High-throughput screening for modulators of cellular contractile forceElectronic supplementary information (ESI) available: Details of any supplementary information available should be included here. See DOI: 10.1039/c5ib00054h by Park, Chan Young, Zhou, Enhua H, Tambe, Dhananjay, Chen, Bohao, Lavoie, Tera, Dowell, Maria, Simeonov, Anton, Maloney, David J, Marinkovic, Aleksandar, Tschumperlin, Daniel J, Burger, Stephanie, Frykenberg, Matthew, Butler, James P, Stamer, W. Daniel, Johnson, Mark, Solway, Julian, Fredberg, Jeffrey J, Krishnan, Ramaswamy

“…When cellular contractile forces are central to pathophysiology, these forces comprise a logical target of therapy. Nevertheless, existing high-throughput…”
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High-throughput screening for modulators of cellular contractile force by Park, Chan Young, Zhou, Enhua H, Tambe, Dhananjay, Chen, Bohao, Lavoie, Tera, Dowell, Maria, Simeonov, Anton, Maloney, David J, Marinkovic, Aleksandar, Tschumperlin, Daniel J, Burger, Stephanie, Frykenberg, Matthew, Butler, James P, Stamer, W. Daniel, Johnson, Mark, Solway, Julian, Fredberg, Jeffrey J, Krishnan, Ramaswamy

“…When cellular contractile forces are central to pathophysiology, these forces comprise a logical target of therapy. Nevertheless, existing high-throughput…”
Get full text