Search Results - "Zhou, De‐Min"

Synthesis and In Vitro Anti-Influenza Virus Evaluation of Novel Sialic Acid (C-5 and C-9)-Pentacyclic Triterpene Derivatives by Han, Xu, Si, Long-Long, Shi, Yong-Ying, Fan, Zi-Bo, Wang, Shou-Xin, Tian, Zhen-Yu, Li, Man, Sun, Jia-Qi, Jiao, Ping-Xuan, Ran, Fu-Xiang, Zhang, Yong-Min, Zhou, De-Min, Xiao, Su-Long

“…The emergence of drug resistant variants of the influenza virus has led to a great need to identify novel and effective antiviral agents. In our previous…”
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The Hydrolysis of RNA:  From Theoretical Calculations to the Hammerhead Ribozyme-Mediated Cleavage of RNA by Zhou, De-Min, Taira, Kazunari

“…Zhou and Taira discuss the most recent reports of theoretical studies on RNA hydrolysis and compare the conclusions from theoretical calculations with the…”
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Synthesis and biological evaluation of echinocystic acid derivatives as HCV entry inhibitors by Yu, Fei, Wang, Qi, Wang, Han, Si, Long-Long, Liu, Jia-Xin, Han, Xu, Xiao, Su-Long, Zhang, Li-He, Zhou, De-Min

“…A series of echinocystic acid （EA） 28-COOH derivatives was synthesized, and their anti-HCV entry activity was evaluated by HCVpp and VSVpp entry assay. It was…”
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Anti-H1N1 virus, cytotoxic and Nrf2 activation activities of chemical constituents from Scutellaria baicalensis by Ji, Shuai, Li, Ru, Wang, Qi, Miao, Wen-juan, Li, Zi-wei, Si, Long-long, Qiao, Xue, Yu, Si-wang, Zhou, De-min, Ye, Min

“…Huang-Qin, derived from the roots of Scutellaria baicalensis Georgi, is a popular Chinese herbal medicine mainly used to treat influenza and cancer. This study…”
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Synthesis of two mono-deoxy β-cyclodextrin derivatives as useful tools for confirming DIBAL-H promoted bis-de-O-methylation mechanism by Xiao, Su Long, Zhou, De Min, Yang, Ming, Yu, Fei, Zhang, Li He, Sinaÿ, Pierre, Zhang, Yong Min

“…Diisobutylaluminium hydride （DIBAL-H） promotes secondary rim regioselective bis-de-O-methylation of permethylated β- cyclodextrin （β-CD） to give diol 2. To…”
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Existence of efficient divalent metal ion-catalyzed and inefficient divalent metal ion-independent channels in reactions catalyzed by a hammerhead ribozyme by Zhou, Jing-Min, Zhou, De-Min, Takagi, Yasuomi, Kasai, Yasuhiro, Inoue, Atsushi, Baba, Tadashi, Taira, Kazunari

“…The hammerhead ribozyme is generally accepted as a well characterized metalloenzyme. However, the precise nature of the interactions of the RNA with metal ions…”
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Elucidation of the pharmacophore of echinocystic acid, a new lead for blocking HCV entry by Wang, Han, Wang, Qi, Xiao, Su-Long, Yu, Fei, Ye, Min, Zheng, Yong-Xiang, Zhao, Chuan-Ke, Sun, Di-An, Zhang, Li-He, Zhou, De-Min

“…To elucidate the pharmacophore of echinocystic acid (EA), an oleanane-type triterpene displaying substantial inhibitory activity on HCV entry, two microbial…”
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Discovery of novel heteroarylmethylcarbamodithioates as potent anticancer agents: Synthesis, structure-activity relationship analysis and biological evaluation by Li, Ying-Bo, Yan, Xu, Li, Ri-Dong, Liu, Peng, Sun, Shao-Qian, Wang, Xin, Cui, Jing-Rong, Zhou, De-Min, Ge, Ze-Mei, Li, Run-Tao

“…A series of new analogs based on the structure of lead compound 10 were designed, synthesized and evaluated for their in vitro anti-cancer activities against…”
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IC-4, a new irreversible EGFR inhibitor, exhibits prominent anti-tumor and anti-angiogenesis activities by Li, Ying-Bo, Wang, Zhong-Qing, Yan, Xu, Chen, Mei-Wan, Bao, Jiao-Lin, Wu, Guo-Sheng, Ge, Ze-Mei, Zhou, De-Min, Wang, Yi-Tao, Li, Run-Tao

“…Highlights • We reported IC-4 as a novel irreversible TKI for EGFR. • IC-4 inhibited proliferation, induced apoptosis and a G2/M arrest in breast cancer cells…”
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Conjugation of cyclodextrin with fullerene as a new class of HCV entry inhibitors by Xiao, Su-long, Wang, Qi, Yu, Fei, Peng, Yi-yun, Yang, Ming, Sollogoub, Matthieu, Sinaÿ, Pierre, Zhang, Yong-min, Zhang, Li-he, Zhou, De-min

“…An α-cyclodextrin–[60]fullerene conjugate with a flexible linker at the secondary face of α-cyclodextrin has been prepared, which displays significant water…”
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Explanation by the Double-Metal-Ion Mechanism of Catalysis for the Differential Metal Ion Effects on the Cleavage Rates of 5′-oxy and 5′-thio Substrates by a Hammerhead Ribozyme by Zhou, D M, Zhang, L H, Taira, K

“…In a previous examination using natural all-RNA substrates that contained either a 5′-oxy or 5′-thio leaving group at the cleavage site, we demonstrated that…”
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Selective oxidation-reduction and esterification of asiatic acid by Pestalotiopsis microspora and anti-HCV activity by Gao, Zhao-Hui, Gao, Ran-Ran, Dong, Xin-Ran, Zou, Zhong-Mei, Wang, Qi, Zhou, De-Min, Sun, Di-An

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GIS SUPPORTED HEDONIC MODEL FOR ASSESSING PROPERTY VALUE IN WEST OAKLAND, CALIFORNIA by Zhou, De-min, Xu, Jian-chun, Gong, Hui-li

“…A hedonic linear regression model is constructed in this paper to estimate property value, In our model, the property value （sales price） is a function of…”
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A model supported by GIS for locating and quantifying PM2.5 emission originated from residential wood burning by Zhou, De-min, Radke, John, Tian, Yong-qian, Xu, Jian-chun, Mu, Lan

“…A research method was presented for spatially quantifying and allocating the potential activity of a fine particle matter emission (PM2.5), which originated…”
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A spatial cluster method supported by GIS for urban-suburban-rural classification by Zhou, De-min, Xu, Jian-chun, Radke, John, Mu, Lan

“…This study was undertaken to construct a preliminary spatial analysis method for building an urban-suburban-rural category in the specific sample area of…”
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Intestinal Absorption of Ergostane and Lanostane Triterpenoids from Antrodia cinnamomea Using Caco-2 Cell Monolayer Model by Wang, Qi, Qiao, Xue, Qian, Yi, Li, Zi-wei, Tzeng, Yew-min, Zhou, De-min, Guo, De-an, Ye, Min

“…Antrodia cinnamomea is a precious medicinal mushroom. It exhibits promising therapeutic effects on cancer, intoxication, hypertension, hepatitis, and…”
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N-9 Alkylation of purines via light-promoted and metal-free radical relay by Mao, Runze, Sun, Lifeng, Wang, Yong-Shi, Zhou, Min-Min, Xiong, De-Cai, Li, Qin, Ye, Xin-Shan

“…A metal-free and light-promoted approach to the synthesis of N-9 alkylated purine nucleoside derivatives, via a CF3 radical triggered radical relay pathway,…”
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Identification of differentially expressed genes related to radioresistance of human esophageal cancer cells by Li, Hong-Zhen, Gao, Xian-Shu, Xiong, Wei, Zhao, Jing, Zhang, Hai, Zhou, De-Min

“…Background and Objective： Radioresistant cells in esophageal cancer is one of the important reasons for the local failure of radiotherapy. In recent years,…”
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Selection of RNA Aptamers that Bind Specifically to the NS3 Protease of Hepatitis C Virus by Urvil, Petri T., Kakiuchi, Nobuko, Zhou, De‐Min, Shimotohno, Kunitada, Kumar, Penmetcha K. R., Nishikawa, Satoshi

“…The RNA genome of human hepatitis C virus (HCV) is translated into a large precursor polyprotein. The NS3 protease of HCV has a crucial role in the processing…”
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Differential gene expression profiles of DNA repair genes in esophageal cancer cells after X-ray irradiation by Zhang, Hai, Gao, Xian-Shu, Zhao, Jing, Xiong, Wei, Zhang, Min, Li, Hong-Zhen, Zhou, De-Min, Jin, Xin, Zhang, Dan-Shen

“…Various factors affect the radioresistance of tumor cells, with unknown molecular mechanism(s). Many genes have been found to associate with the…”
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