Search Results - "Zhou, Chengfang"

Genetic transformation system for Bacillus velezensis NSZ-YBGJ001 and curing of the endogenous plasmid pBV01 by Tian, Hui, Liu, Bo, Yang, Juan, Zhou, Chengfang, Xu, Xinxin, Zhang, Yuhong, Lu, Zhijun, Zhang, Wei

“…Objectives To construct a genetic transformation system for Bacillus velezensis NSZ-YBGJ001 and identify the origin element in an endogenous plasmidpBV01 for…”
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Insufficiency of FZR1 disturbs HSC quiescence by inhibiting ubiquitin-dependent degradation of RUNX1 in aplastic anemia by Zhou, Chengfang, Kuang, Mei, Liu, Zhilong, Jia, Xiaoqin, Chen, Zhe, Liu, Yuanyuan, Li, Zhigang, Wu, Weiru, Ma, Le, Chen, Jieping, Hou, Yu

“…FZR1 has been implicated as a master regulator of the cell cycle and quiescence, but its roles and molecular mechanisms in the pathogenesis of severe aplastic…”
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A Cdh1–FoxM1–Apc axis controls muscle development and regeneration by Chen, Zhe, Li, Lei, Xu, Shuangnian, Liu, Zhilong, Zhou, Chengfang, Li, Zhigang, Liu, Yuanyuan, Wu, Weiru, Huang, Yongxiu, Kuang, Mei, Fan, Shijun, Li, Hui, Li, Xi, Song, Guanbin, Wu, Wen-Shu, Chen, Jieping, Hou, Yu

“…Forkhead box M1 (FoxM1) transcriptional factor has a principal role in regulating cell proliferation, self-renewal, and tumorigenesis. However, whether FoxM1…”
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Alkbh5 plays indispensable roles in maintaining self-renewal of hematopoietic stem cells by Yang, Bijie, Liu, Yuanyuan, Xiao, Feifei, Liu, Zhilong, Chen, Zhe, Li, Zhigang, Zhou, Chengfang, Kuang, Mei, Shu, Yi, Liu, Shan, Zou, Lin

“…is one of the primary demethylases responsible for reversing N6-methyladenosine (m A) modifications on mRNAs, and it plays a crucial role in many physiological…”
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Zfp521 is essential for the quiescence and maintenance of adult hematopoietic stem cells under stress by Li, Zhigang, Fu, Xuemei, Wu, Weiru, Liu, Zhilong, Chen, Zhe, Zhou, Chengfang, Liu, Yuanyuan, Kuang, Mei, Sun, Fangfang, Xiao, Feifei, Huang, Yongxiu, Zhang, Xiaojun, Fan, Shijun, Huang, Xingqin, Zheng, Guangling, Chen, Jieping, Hou, Yu

“…Zinc finger protein 521 (Zfp521), a quiescent hematopoietic stem cell (HSC)-enriched transcription factor, is involved in the self-renewal and differentiation…”
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Nynrin Preserves Hematopoietic Stem Cell Function Via the Ppif-Mediated Mitochondrial Permeability Transition by Zhou, Chengfang, Kuang, Mei, Wang, Jianming, Luo, Yu, Hou, Yu

“…Mitochondria have recently been identified as a critical regulator for homeostasis of hematopoietic stem cells (HSCs). However, the mechanism underlying HSC…”
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Fzr1 Preserves Hematopoietic Stem Cell Quiescence through Inhibiting Runx1 by Zhou, Chengfang, Kuang, Mei, Chen, Jieping, Hou, Yu

“…Regulated blood production is achieved through the hierarchical organization of dormant hematopoietic stem cell (HSC) subsets that differ in self-renewal…”
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Existence of nontrivial solutions for a class of biharmonic equations with singular potential in R N \(\mathbb{R}^{N}\) by Zhou, Chengfang, Ouyang, Zigen

“…In this paper, we study a class of biharmonic equations with a singular potential in RN\(\mathbb{R}^{N}\). Under appropriate assumptions on the nonlinearity,…”
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Existence of nontrivial solutions for a class of biharmonic equations with singular potential in R N $\mathbb{R}^{N} by Zhou, Chengfang, Ouyang, Zigen

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Nynrin preserves hematopoietic stem cell function by inhibiting the mitochondrial permeability transition pore opening by Zhou, Chengfang, Kuang, Mei, Tao, Yin, Wang, Jianming, Luo, Yu, Fu, Yinghao, Chen, Zhe, Liu, Yuanyuan, Li, Zhigang, Wu, Weiru, Wang, Li, Dou, Ying, Wang, Junping, Hou, Yu

“…Mitochondria are key regulators of hematopoietic stem cell (HSC) homeostasis. Our research identifies the transcription factor Nynrin as a crucial regulator of…”
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The role of FZR1 in tumorigenesis: Focus on cell-cycle control by LI, HUI, ZHOU, CHENGFANG, KUANG, MEI, LIU, YUN, CHEN, JIEPING

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Nuclear DEK preserves hematopoietic stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis by Chen, Zhe, Huo, Dawei, Li, Lei, Liu, Zhilong, Li, Zhigang, Xu, Shuangnian, Huang, Yongxiu, Wu, Weiru, Zhou, Chengfang, Liu, Yuanyuan, Kuang, Mei, Wu, Feng, Li, Hui, Qian, Pengxu, Song, Guanbin, Wu, Xudong, Chen, Jieping, Hou, Yu

“…The oncogene DEK is found fused with the NUP214 gene creating oncoprotein DEK-NUP214 that induces acute myeloid leukemia (AML) in patients, and secreted DEK…”
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Preparation, characterization, and pharmacodynamic study on deep second degree burns of total flavonoids composite phospholipids liposome gel of Oxytropis falcata Bunge by Zeng, Qiping, Cai, Xiaohui, Cao, Yixiang, Zhou, Chengfang, Yu, Le, Chen, Jinshan

“…Wound healing is the treatment problem after deep second degree (II°) burns. The p38 mitogen-activated protein kinase (p38 MAPK) and nuclear…”
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Existence of nontrivial solutions for a class of biharmonic equations with singular potential in RN by Zhou, Chengfang, Ouyang, Zigen

“…In this paper, we study a class of biharmonic equations with a singular potential in R N . Under appropriate assumptions on the nonlinearity, we establish some…”
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Existence of nontrivial solutions for a class of biharmonic equations with singular potential in RN $\mathbb{R}^{N} by Chengfang Zhou, Zigen Ouyang

“…Abstract In this paper, we study a class of biharmonic equations with a singular potential in RN $\mathbb{R}^{N}$. Under appropriate assumptions on the…”
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Dissecting the role of cell signaling versus CD8+ T cell modulation in propranolol antitumor activity by Li, Wei, Wan, Jielin, Chen, Cuiyu, Zhou, Chengfang, Liao, Ping, Hu, Qian, Hu, Jiali, Wang, Yang, Zhang, Yu, Peng, Cong, Huang, Yuanfei, Huang, Weihua, Zhang, Wei, Mcleod, Howard L., He, Yijing

“…Preclinical and early clinical mechanistic studies of antitumor activity from the beta-adrenergic receptor (β-AR) blocker propranolol have revealed both cell…”
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Abstract 4567: Immunoclassification of gastric cancer in the context of clinical outcome by Wang, Weili, Liao, Ping, Xie, Shangchen, Shen, Dongya, Zhou, Chengfang, Mcleod, Howard, He, Yijing

“…Background: Gastric cancer (GC) plays a leading role in all cancer deaths especially in Eastern Asia. Current classifications including WHO, Lauren, and TCGA…”
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Propranolol induced G0/G1/S phase arrest and apoptosis in melanoma cells via AKT/MAPK pathway by Zhou, Chengfang, Chen, Xiang, Zeng, Weiqi, Peng, Cong, Huang, Gang, Li, Xian'an, Ouyang, Zhengxiao, Luo, Yi, Xu, Xuezheng, Xu, Biaobo, Wang, Weili, He, Ruohui, Zhang, Xu, Zhang, Liyang, Liu, Jie, Knepper, Todd C, He, Yijing, McLeod, Howard L

“…Both preclinical and epidemiology studies associate β-adrenoceptors-blockers (β-blockers) with activity against melanoma. However, the underlying mechanism is…”
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EBV infection and MSI status significantly influence the clinical outcomes of gastric cancer patients by Shen, Hua, Zhong, Meizuo, Wang, Weili, Liao, Ping, Yin, Xianli, Rotroff, Daniel, Knepper, Todd C., Mcleod, Howard L., Zhou, Chengfang, Xie, Shangchen, Li, Wei, Xu, Biaobo, He, Yijing

“…Epstein-Barr virus (EBV) and microsatellite instability (MSI) are associated with the carcinogenesis of many kinds of tumors, including gastric cancer (GC)…”
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Propranolol enhanced the anti-tumor effect of sunitinib by inhibiting proliferation and inducing G0/G1/S phase arrest in malignant melanoma by Kuang, Xinwei, Qi, Min, Peng, Cong, Zhou, Chengfang, Su, Juan, Zeng, Weiqi, Liu, Hong, Zhang, Jianglin, Chen, Mingliang, Shen, Minxue, Xie, Xiaoyun, Li, Fangfang, Zhao, Shuang, Li, Qingling, Luo, Zhongling, Chen, Junchen, Tao, Juan, He, Yijing, Chen, Xiang

“…Both sunitinib, a multi-target tyrosine kinase inhibitor (TKI) and propranolol, a non-selective β-blocker, have proven therapeutic effects on malignant…”
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