Search Results - "Zhou, Bo O."

Leptin-Receptor-Expressing Mesenchymal Stromal Cells Represent the Main Source of Bone Formed by Adult Bone Marrow by Zhou, Bo O., Yue, Rui, Murphy, Malea M., Peyer, James G., Morrison, Sean J.

“…Studies of the identity and physiological function of mesenchymal stromal cells (MSCs) have been hampered by a lack of markers that permit both prospective…”
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Leptin Receptor Promotes Adipogenesis and Reduces Osteogenesis by Regulating Mesenchymal Stromal Cells in Adult Bone Marrow by Yue, Rui, Zhou, Bo O., Shimada, Issei S., Zhao, Zhiyu, Morrison, Sean J.

“…Skeletal stem cells (SSCs) that are the major source of osteoblasts and adipocytes in adult bone marrow express leptin receptor (LepR). To test whether LepR…”
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Tracing the skeletal progenitor transition during postnatal bone formation by Shu, Hui Sophie, Liu, Yiming Liam, Tang, Xinyu Thomas, Zhang, Xinyi Shirley, Zhou, Bin, Zou, Weiguo, Zhou, Bo O.

“…Multiple distinct types of skeletal progenitors have been shown to contribute to endochondral bone development and maintenance. However, the division of labor…”
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A perisinusoidal niche for extramedullary haematopoiesis in the spleen by Inra, Christopher N., Zhou, Bo O., Acar, Melih, Murphy, Malea M., Richardson, James, Zhao, Zhiyu, Morrison, Sean J.

“…Haematopoietic stresses mobilize haematopoietic stem cells (HSCs) from the bone marrow to the spleen and induce extramedullary haematopoiesis (EMH). However,…”
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Bone marrow adipocytes promote the regeneration of stem cells and haematopoiesis by secreting SCF by Zhou, Bo O., Yu, Hua, Yue, Rui, Zhao, Zhiyu, Rios, Jonathan J., Naveiras, Olaia, Morrison, Sean J.

“…Endothelial cells and leptin receptor + (LepR + ) stromal cells are critical sources of haematopoietic stem cell (HSC) niche factors, including stem cell…”
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Hematopoietic stem and progenitor cells regulate the regeneration of their niche by secreting Angiopoietin-1 by Zhou, Bo O, Ding, Lei, Morrison, Sean J

“…Hematopoietic stem cells (HSCs) are maintained by a perivascular niche in bone marrow but it is unclear whether the niche is reciprocally regulated by HSCs…”
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ANGPTL2-containing small extracellular vesicles from vascular endothelial cells accelerate leukemia progression by Huang, Dan, Sun, Guohuan, Hao, Xiaoxin, He, Xiaoxiao, Zheng, Zhaofeng, Chen, Chiqi, Yu, Zhuo, Xie, Li, Ma, Shihui, Liu, Ligen, Zhou, Bo O, Cheng, Hui, Zheng, Junke, Cheng, Tao

“…Small extracellular vesicles (SEVs) are functional messengers of certain cellular niches that permit noncontact cell communications. Whether niche-specific…”
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Perivenous Stellate Cells Are the Main Source of Myofibroblasts and Cancer‐Associated Fibroblasts Formed After Chronic Liver Injuries by Wang, Shan‐Shan, Tang, Xinyu Thomas, Lin, Minghui, Yuan, Jia, Peng, Yi Jacky, Yin, Xiujuan, Shang, GuoGuo, Ge, Gaoxiang, Ren, Zhenggang, Zhou, Bo O.

“…Background and Aims Studies of the identity and pathophysiology of fibrogenic HSCs have been hampered by a lack of genetic tools that permit specific and…”
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Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation by Bian, Chuanbing, Xu, Chao, Ruan, Jianbin, Lee, Kenneth K, Burke, Tara L, Tempel, Wolfram, Barsyte, Dalia, Li, Jing, Wu, Minhao, Zhou, Bo O, Fleharty, Brian E, Paulson, Ariel, Allali-Hassani, Abdellah, Zhou, Jin-Qiu, Mer, Georges, Grant, Patrick A, Workman, Jerry L, Zang, Jianye, Min, Jinrong

“…The SAGA (Spt–Ada–Gcn5 acetyltransferase) complex is an important chromatin modifying complex that can both acetylate and deubiquitinate histones. Sgf29 is a…”
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ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells by Liu, Xiaojing, Liu, Tingting, Shang, Yafang, Dai, Pengfei, Zhang, Wubing, Lee, Brian J., Huang, Min, Yang, Dingpeng, Wu, Qiu, Liu, Liu Daisy, Zheng, Xiaoqi, Zhou, Bo O., Dong, Junchao, Yeap, Leng-Siew, Hu, Jiazhi, Xiao, Tengfei, Zha, Shan, Casellas, Rafael, Liu, X. Shirley, Meng, Fei-Long

“…Programmed DNA recombination in mammalian cells occurs predominantly in a directional manner. While random DNA breaks are typically repaired both by deletion…”
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Microbiota-derived lactate promotes hematopoiesis and erythropoiesis by inducing stem cell factor production from leptin receptor+ niche cells by Lee, Yong-Soo, Kim, Tae-Young, Kim, Yeji, Kim, Seungil, Lee, Su-Hyun, Seo, Sang-Uk, Zhou, Bo O., Eunju, O., Kim, Kwang Soon, Kweon, Mi-Na

“…Although functional interplay between intestinal microbiota and distant sites beyond the gut has been identified, the influence of microbiota-derived…”
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Swc4 positively regulates telomere length independently of its roles in NuA4 and SWR1 complexes by Liu, Jia-Cheng, Li, Qian-Jin, He, Ming-Hong, Hu, Can, Dai, Pengfei, Meng, Fei-Long, Zhou, Bo O, Zhou, Jin-Qiu

“…Abstract Telomeres at the ends of eukaryotic chromosomes are essential for genome integrality and stability. In order to identify genes that sustain telomere…”
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Lepr‐Expressing PDLSCs Contribute to Periodontal Homeostasis and Respond to Mechanical Force by Piezo1 by Zhang, Danting, Lin, Weimin, Jiang, Shuang, Deng, Peng, Liu, Linfeng, Wang, Qian, Sheng, Rui, Shu, Hui Sophie, Wang, Lijun, Zou, Weiguo, Zhou, Bo O., Jing, Junjun, Ye, Ling, Yu, Bo, Zhang, Shiwen, Yuan, Quan

“…Periodontium supports teeth in a mechanically stimulated tissue environment, where heterogenous stem/progenitor populations contribute to periodontal…”
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Histone H3 Lysine 4 Hypermethylation Prevents Aberrant Nucleosome Remodeling at the PHO5 Promoter by Wang, Shan-Shan, Zhou, Bo O., Zhou, Jin-Qiu

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Recent Transcription-induced Histone H3 Lysine 4 (H3K4) Methylation Inhibits Gene Reactivation by Zhou, Bo O., Zhou, Jin-Qiu

“…Recent transcription of GAL genes transiently leaves an H3K4 methylation mark at their promoters, providing an epigenetic memory for the recent transcriptional…”
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The N-terminus of Histone H3 Is Required for de Novo DNA Methylation in Chromatin by Hu, Jia-Lei, Zhou, Bo O., Zhang, Run-Rui, Zhang, Kang-Ling, Zhou, Jin-Qiu, Xu, Guo-Liang, Riggs, Arthur D.

“…DNA methylation and histone modification are two major epigenetic pathways that interplay to regulate transcriptional activity and other genome functions…”
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Histone H4 lysine 12 acetylation regulates telomeric heterochromatin plasticity in Saccharomyces cerevisiae by Zhou, Bo O, Wang, Shan-Shan, Zhang, Yang, Fu, Xiao-Hong, Dang, Wei, Lenzmeier, Brian A, Zhou, Jin-Qiu

“…Recent studies have established that the highly condensed and transcriptionally silent heterochromatic domains in budding yeast are virtually dynamic…”
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C-KIT Expression Distinguishes Fetal from Postnatal Skeletal Progenitors by He, Di Demi, Tang, Xinyu Thomas, Dong, Wenjie, Cui, Guizhong, Peng, Guangdun, Yin, Xiujuan, Chen, Yujie, Jing, Naihe, Zhou, Bo O.

“…Hematopoietic stem cells (HSCs) and skeletal stem cells (SSCs) cohabit in the bone marrow. KITL (C-KIT ligand) from LEPR+ adult bone marrow stromal cells is…”
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Leptin receptor–expressing cells represent a distinct subpopulation of notochord-derived cells and are essential for disc homoeostasis by Gao, Bo, Yin, Jinhua, Xu, Xiaolong, Fan, Jing, Wang, Di, Zheng, Chao, Lu, Weiguang, Cheng, Pengzhen, Sun, Jicheng, Wang, Dong, Li, Lu, Zhou, Bo O., Yang, Liu, Luo, Zhuojing

“…Intervertebral disc degeneration (IDD) remains to be an intractable clinical challenge. Although IDD is characterised by loss of notochordal cells (NCs) and…”
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Histone deacetylase Rpd3 antagonizes Sir2-dependent silent chromatin propagation by Zhou, Jing, Zhou, Bo O, Lenzmeier, Brian A, Zhou, Jin-Qiu

“…In the eukaryotic genome, transcriptionally silent chromatin tends to propagate along a chromosome and encroach upon adjacent active chromatin. The silencing…”
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