Search Results - "Zhongjian Chen"

Adapting liposomes for oral drug delivery by He, Haisheng, Lu, Yi, Qi, Jianping, Zhu, Quangang, Chen, Zhongjian, Wu, Wei

“…Liposomes mimic natural cell membranes and have long been investigated as drug carriers due to excellent entrapment capacity, biocompatibility and safety…”
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Metabolism of flavonoids in human: a comprehensive review by Chen, Zhongjian, Zheng, Shirui, Li, Liping, Jiang, Huidi

“…Flavonoids are naturally occurring polyphenols, which are widely taken in diets, supplements and herbal medicines. Epidemiological studies have shown a…”
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Ionic liquids as a useful tool for tailoring active pharmaceutical ingredients by Wu, Xiying, Zhu, Quangang, Chen, Zhongjian, Wu, Wei, Lu, Yi, Qi, Jianping

“…Ionic liquids (ILs) have been widely used in biomedical and pharmaceutical fields as solvents or permeation enhancers. Recently, more and more researchers…”
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Oral delivery of proteins and peptides: Challenges, status quo and future perspectives by Zhu, Quangang, Chen, Zhongjian, Paul, Pijush Kumar, Lu, Yi, Wu, Wei, Qi, Jianping

“…Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules than small molecular drugs due to their high selectivity and efficacy,…”
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Liposome-based delivery of biological drugs by Thapa Magar, Kosheli, Boafo, George Frimpong, Li, Xiaotong, Chen, Zhongjian, He, Wei

“…Biological drugs are attracting tremendous attention in disease treatment. However, their application is significantly limited by their inherent properties,…”
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Utility of Pickering emulsions in improved oral drug delivery by Tai, Zongguang, Huang, Yanping, Zhu, Quangang, Wu, Wei, Yi, Tao, Chen, Zhongjian, Lu, Yi

“…[Display omitted] •Properties of particle stabilizers are crucial to construct Pickering emulsions.•Pickering emulsions enhance bioavailability or…”
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Biological drug and drug delivery-mediated immunotherapy by Xiao, Qingqing, Li, Xiaotong, Li, Yi, Wu, Zhenfeng, Xu, Chenjie, Chen, Zhongjian, He, Wei

“…The initiation and development of major inflammatory diseases, i.e., cancer, vascular inflammation, and some autoimmune diseases are closely linked to the…”
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Pulmonary delivery of siRNA against acute lung injury/acute respiratory distress syndrome by Zoulikha, Makhloufi, Xiao, Qingqing, Boafo, George Frimpong, Sallam, Marwa A., Chen, Zhongjian, He, Wei

“…The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of several unmet medical needs, including acute lung injury/acute…”
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GC–MS-based metabolomic study reveals dynamic changes of chemical compositions during black tea processing by Wu, Hualing, Huang, Wenjie, Chen, Zhongjian, Chen, Zhuang, Shi, Jingfang, Kong, Qian, Sun, Shili, Jiang, Xiaohui, Chen, Dong, Yan, Shijuan

“…The chemical composition of black tea during tea processing is in a state of flux. However, the dynamic changes of this sophisticated metabolic process are far…”
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Current research trends of nanomedicines by Liu, Qiuyue, Zou, Jiahui, Chen, Zhongjian, He, Wei, Wu, Wei

“…Owing to the inherent shortcomings of traditional therapeutic drugs in terms of inadequate therapeutic efficacy and toxicity in clinical treatment,…”
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Overcoming the resistance mechanisms of Smoothened inhibitors by Dong, Xiaochun, Wang, Chenglin, Chen, Zhongjian, Zhao, Weili

“…•The possible mechanism of acquired resistance to Smo inhibitors was reviewed.•Development of second-generation inhibitors is critical to combat Smo…”
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Large-scale targeted metabolomics method for metabolite profiling of human samples by Cao, Guodong, Song, Zhengbo, Hong, Yanjun, Yang, Zhiyi, Song, Yuanyuan, Chen, Zhongjian, Chen, Zhaobin, Cai, Zongwei

“…Targeted metabolomics has significant advantages for quantification but suffers from reduced metabolite coverage. In this study, we developed a large-scale…”
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Integrated proteomics and metabolomics reveals the comprehensive characterization of antitumor mechanism underlying Shikonin on colon cancer patient-derived xenograft model by Chen, Yang, Ni, Juan, Gao, Yun, Zhang, Jinghui, Liu, Xuesong, Chen, Yong, Chen, Zhongjian, Wu, Yongjiang

“…Colorectal cancer (CRC) is a common malignancy occurring in the digestive system. Despite progress in surgery and therapy options, CRC is still a considerable…”
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Improving dermal delivery of hydrophilic macromolecules by biocompatible ionic liquid based on choline and malic acid by Wu, Xiying, Chen, Zhongjian, Li, Yang, Yu, Qin, Lu, Yi, Zhu, Quangang, Li, Ying, An, Duopeng, Qi, Jianping, Wu, Wei

“…[Display omitted] The aim of this work was to develop biocompatible ionic liquids (ILs) for enhancement of dermal delivery of hydrophilic macromolecules. The…”
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Editorial: Epithelial immune microenvironment and inflammatory skin diseases by Chen, Zhongjian, Xu, Xiaowei, Lu, Yi

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Preoperative serum bilirubin is an independent prognostic factor for curatively resected esophageal squamous cell carcinoma by Huang, Xiancong, Chen, Yang, Yang, Huan, Wang, Ruting, Chen, Zhongjian

“…This study examines prognostic value of preoperative serum bilirubin, including unconjugated bilirubin (UCB), conjugated bilirubin (CB), and total bilirubin…”
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Machine learning applied to near-infrared spectra for clinical pleural effusion classification by Chen, Zhongjian, Chen, Keke, Lou, Yan, Zhu, Jing, Mao, Weimin, Song, Zhengbo

“…Lung cancer patients with malignant pleural effusions (MPE) have a particular poor prognosis. It is crucial to distinguish MPE from benign pleural effusion…”
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Lipid carriers for mRNA delivery by Zhang, Wanting, Jiang, Yuxin, He, Yonglong, Boucetta, Hamza, Wu, Jun, Chen, Zhongjian, He, Wei

“…Messenger RNA (mRNA) is the template for protein biosynthesis and is emerging as an essential active molecule to combat various diseases, including viral…”
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Overcoming or circumventing the stratum corneum barrier for efficient transcutaneous immunization by Chen, Zhongjian, Lv, Yongjiu, Qi, Jianping, Zhu, Quangang, Lu, Yi, Wu, Wei

“…•Stratum corneum presents as a barrier to efficient TCI.•Physical devices improve transcutaneous immunization via an invasive manner.•Transfollicular route is…”
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Vascular Endothelial Growth Factor A VEGFA Inhibition: An Effective Treatment Strategy for Psoriasis by Chen, Ya, Tai, Zongguang, Zhu, Congcong, Yu, Qin, Zhu, Quangang, Chen, Zhongjian

“…Psoriasis is an inflammatory skin disease mediated by the immune system and characterized by an inflammatory ring, also known as an epithelial immune…”
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