Search Results - "Zhong, Zhenyu"
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Autophagy, Inflammation, and Immunity: A Troika Governing Cancer and Its Treatment
Published in Cell (14-07-2016)“…Autophagy, a cellular waste disposal process, has well-established tumor-suppressive properties. New studies indicate that, in addition to its cell-autonomous…”
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Screening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinoma
Published in Scientific reports (03-08-2016)“…Circular RNAs (circRNAs), a kind of non-coding RNAs, have shown large capabilities in gene regulation. However, the mechanisms underlying circRNAs remain…”
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3
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
Published in Nature (London) (01-08-2018)“…Dysregulated NLRP3 inflammasome activity results in uncontrolled inflammation, which underlies many chronic diseases. Although mitochondrial damage is needed…”
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4
Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity
Published in Nature (London) (16-11-2017)“…IgA + B cells expressing programmed death ligand 1 (PD-L1) and interleukin 10 accumulate in the inflamed livers of humans and mice with non-alcoholic fatty…”
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p62, Upregulated during Preneoplasia, Induces Hepatocellular Carcinogenesis by Maintaining Survival of Stressed HCC-Initiating Cells
Published in Cancer cell (13-06-2016)“…p62 is a ubiquitin-binding autophagy receptor and signaling protein that accumulates in premalignant liver diseases and most hepatocellular carcinomas (HCCs)…”
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6
A multiple modulation synthesis method with high spatial resolution for noninvasive neurostimulation
Published in PloS one (20-06-2019)“…Noninvasive neurostimulation plays a pivotal role in the direct control of neural circuits and the modulation of neuronal function. However, it is difficult to…”
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Reversing extinction in China's Père David's deer
Published in Science (American Association for the Advancement of Science) (12-02-2021)Get full text
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Molecular mechanisms and topological consequences of drastic chromosomal rearrangements of muntjac deer
Published in Nature communications (25-11-2021)“…Muntjac deer have experienced drastic karyotype changes during their speciation, making it an ideal model for studying mechanisms and functional consequences…”
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9
Comparison of Clinical Features and Visual Outcome between Sympathetic Ophthalmia and Vogt–Koyanagi–Harada Disease in Chinese Patients
Published in Ophthalmology (Rochester, Minn.) (01-09-2019)“…To characterize the clinical features of sympathetic ophthalmia (SO) and compare SO and Vogt–Koyanagi–Harada (VKH) disease in Chinese patients. Retrospective…”
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Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis
Published in Immunity (Cambridge, Mass.) (18-12-2014)“…Interleukin-17A (IL-17A) is a pro-inflammatory cytokine linked to rapid malignant progression of colorectal cancer (CRC) and therapy resistance. IL-17A exerts…”
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11
Advances in Sorptive Removal of Hexavalent Chromium (Cr(VI)) in Aqueous Solutions Using Polymeric Materials
Published in Polymers (11-01-2023)“…Sorptive removal of hexavalent chromium (Cr(VI)) bears the advantages of simple operation and easy construction. Customized polymeric materials are the…”
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Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria
Published in The Journal of biological chemistry (16-08-2019)“…Excessive alcohol consumption induces intestinal dysbiosis of the gut microbiome and reduces gut epithelial integrity. This often leads to portal…”
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Zn/Sr dual ions-collagen co-assembly hydroxyapatite enhances bone regeneration through procedural osteo-immunomodulation and osteogenesis
Published in Bioactive materials (01-04-2022)“…The immune microenvironment induced by biomaterials played vital roles in bone regeneration. Hydroxyapatite (HA) and its ion-substituted derivates represent a…”
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14
The molecular anatomy of cashmere goat hair follicle during cytodifferentiation stage
Published in BMC genomics (15-10-2024)“…Cashmere, named as "soft gold", derives from the secondary hair follicles (SHFs) of cashmere goat which is vital to Northwest China's economy. The…”
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NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice
Published in Gastroenterology (New York, N.Y. 1943) (01-03-2019)“…Although there are associations among oxidative stress, reduced nicotinamide adenine dinucleotide phosphate oxidase (NOX) activation, and hepatocellular…”
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Integrated Analysis of Key Pathways and Drug Targets Associated With Vogt-Koyanagi-Harada Disease
Published in Frontiers in immunology (15-12-2020)“…Vogt-Koyanagi-Harada (VKH) disease is a complex disease associated with multiple molecular immunological mechanisms. As the underlying mechanism for VKH…”
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Potential escalator-related injury identification and prevention based on multi-module integrated system for public health
Published in Machine vision and applications (01-03-2022)“…Escalator-related injuries threaten public health with the widespread use of escalators. The existing studies tend to focus on after-the-fact statistics,…”
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Lychee Fruit Detection Based on Monocular Machine Vision in Orchard Environment
Published in Sensors (Basel, Switzerland) (21-09-2019)“…Due to the change of illumination environment and overlapping conditions caused by the neighboring fruits and other background objects, the simple application…”
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Data augmentation based on multiple oversampling fusion for medical image segmentation
Published in PloS one (18-10-2022)“…A high-performance medical image segmentation model based on deep learning depends on the availability of large amounts of annotated training data. However, it…”
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Assessment of External Properties for Identifying Banana Fruit Maturity Stages Using Optical Imaging Techniques
Published in Sensors (Basel, Switzerland) (01-07-2019)“…The maturity stage of bananas has a considerable influence on the fruit postharvest quality and the shelf life. In this study, an optical imaging based method…”
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