Search Results - "Zhong, Yixi"
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1
Moderate mutation rate in the SARS coronavirus genome and its implications
Published in BMC evolutionary biology (28-06-2004)“…The outbreak of severe acute respiratory syndrome (SARS) caused a severe global epidemic in 2003 which led to hundreds of deaths and many thousands of…”
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2
Global genetic variation at nine short tandem repeat loci and implications on forensic genetics
Published in European journal of human genetics : EJHG (01-01-2003)“…We have studied genetic variation at nine autosomal short tandem repeat loci in 20 globally distributed human populations defined by geographic and ethnic…”
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3
Genetic admixture in three mexican mestizo populations based on D1S80 and HLA-DQA1 Loci
Published in American journal of human biology (01-03-2002)“…This study compares genetic polymorphisms at the D1S80 and HLA‐DQA1 loci in three Mexican Mestizo populations from three large states (Nuevo León, Jalisco, and…”
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4
Nondetectability of restriction fragments and independence of DNA fragment sizes within and between Loci in RFLP typing of DNA
Published in American journal of human genetics (01-08-1994)“…We provide experimental evidence showing that, during the restriction-enzyme digestion of DNA samples, some of the HaeIII-digested DNA fragments are small…”
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5
Patterns of Instability of Expanded CAG Repeats at the ERDA1 Locus in General Populations
Published in American journal of human genetics (01-07-1999)“…A highly polymorphic CAG repeat locus, ERDA1, was recently described on human chromosome 17q21.3, with alleles as large as 50–90 repeats and without any…”
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6
Genetic variation at twentythree microsatellite loci in sixteen human populations
Published in Journal of genetics (01-08-1999)“…We have analysed genetic variation at 23 microsatellite loci in a global sample of 16 ethnically and geographically diverse human populations. On the basis of…”
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7
The utility of short tandem repeat loci beyond human identification: Implications for development of new DNA typing systems
Published in Electrophoresis (01-01-1999)“…Since the first characterization of the population genetic properties of repeat polymorphisms, the number of short tandem repeat (STR) loci validated for…”
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8
Development of a Highly Polymorphic STR Marker for Identity Testing Purposes at the Human Androgen Receptor Gene (HUMARA)
Published in Journal of forensic sciences (01-09-1998)“…We developed a non-isotopic method which improves the technical quality of the X-linked HUMARA locus typing process. The use of formamide and a low…”
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9
Rate and directionality of mutations and effects of allele size constraints at anonymous, gene-associated, and disease-causing trinucleotide loci
Published in Molecular biology and evolution (01-09-1999)“…We studied the patterns of within- and between-population variation at 29 trinucleotide loci in a random sample of 200 healthy individuals from four diverse…”
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10
Distribution and evolution of CTG repeats at the myotonin protein kinase gene in human populations
Published in Genome research (01-02-1996)“…We have analyzed the CTG repeat length and the neighboring Alu insertion/deletion (+/-) polymorphism in DNA samples from 16 ethnically and geographically…”
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11
Statistical power of an exact test of Hardy-Weinberg proportions of genotypic data at a multiallelic locus
Published in Human heredity (01-01-1994)“…A computer algorithm for numerical evaluation of the statistical power of an exact test of Hardy-Weinberg genotypic proportions (HWP), developed here,…”
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12
Paternity evaluation in cases lacking a mother and nondetectable alleles
Published in International journal of legal medicine (01-05-1994)“…In parentage testing the formulae for computing paternity index and exclusion probability generally ignores the presence of nondetectable alleles at the loci…”
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13
A comparative study of genetic variation at five VNTR loci in three ethnic groups of Houston, Texas
Published in Journal of forensic sciences (01-11-1995)“…Following the technique of Southern blot restriction fragment length polymorphisms (RFLP) analysis, we generated a database of DNA profiles at five Variable…”
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14
On allele frequency computation from DNA typing data
Published in International journal of legal medicine (01-03-1993)“…Forensic applications of DNA typing data require the estimation of the frequencies of all observed alleles, which is currently done by a fixed set of groupings…”
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15
Estimation of mutation rates from parentage exclusion data: applications to STR and VNTR loci
Published in Mutation research (05-07-1996)“…Nonpaternity is a common source of bias in estimating mutation rates when they are obtained from family data showing discordance of parental and children's…”
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