Search Results - "Zhong, Wen Yan"

Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-label, phase 3 study by Diaz, Luis A, Shiu, Kai-Keen, Kim, Tae-Won, Jensen, Benny Vittrup, Jensen, Lars Henrik, Punt, Cornelis, Smith, Denis, Garcia-Carbonero, Rocio, Benavides, Manuel, Gibbs, Peter, de la Fourchardiere, Christelle, Rivera, Fernando, Elez, Elena, Le, Dung T, Yoshino, Takayuki, Zhong, Wen Yan, Fogelman, David, Marinello, Patricia, Andre, Thierry

“…Pembrolizumab has shown improved progression-free survival versus chemotherapy in patients with newly diagnosed microsatellite instability-high or mismatch…”
Get full text

Pembrolizumab versus paclitaxel for previously treated advanced gastric or gastroesophageal junction cancer (KEYNOTE‐063): A randomized, open‐label, phase 3 trial in Asian patients by Chung, Hyun Cheol, Kang, Yoon‐Koo, Chen, Zhendong, Bai, Yuxian, Wan Ishak, Wan Zamaniah, Shim, Byoung Yong, Park, Young Lee, Koo, Dong‐Hoe, Lu, Jianwei, Xu, Jianming, Chon, Hong Jae, Bai, Li‐Yuan, Zeng, Shan, Yuan, Ying, Chen, Yen‐Yang, Gu, Kangsheng, Zhong, Wen Yan, Kuang, Shu, Shih, Chie‐Schin, Qin, Shu‐Kui

“…Background KEYNOTE‐063 (NCT03019588) investigated pembrolizumab versus paclitaxel as second‐line therapy in Asian patients with advanced programmed death…”
Get full text

Prevalence, risk factors and genotype distribution of Toxoplasma gondii DNA in soil in China by Cong, Wei, Zhang, Nian-Zhang, Hu, Rui-Si, Zou, Feng-Cai, Zou, Yang, Zhong, Wen-Yan, Wu, Jing-Jing, Fallaize, Christopher J., Zhu, Xing-Quan, Elsheikha, Hany M.

“…In the present study, we performed a cross-sectional survey to determine the occurrence and genotype distribution of T. gondii DNA in soil samples collected…”
Get full text

Health-related quality of life (HRQoL) impact of pembrolizumab (pembro) plus best supportive care (BSC) versus placebo (PBO) plus BSC as second-line (2L) therapy in patients (pts) in Asia with advanced hepatocellular carcinoma (HCC): Phase 3 KEYNOTE-394 study by Qin, Shukui, Fang, Weijia, Ren, ZhengGang, Shuangyan, Ou, Lim, Ho Yeong, Zhang, Feng, Choi, Hye Jin, Tong, Jiandong, Tao, Min, Xu, Aibing, Cheng, Ashley Chi Kin, Lu, Chang-Hsien, Chiu, Chang-Fang, Wahid, Mohamed Ibrahim A., Kamble, Shital, Norquist, Josephine M., Zhong, Wen Yan, Li, Chen, Chen, Zhendong

“…4088 Background: In the randomized, double-blind, phase 3 KEYNOTE-394 trial (NCT03062358), pembro + BSC vs PBO + BSC as 2L therapy significantly reduced the…”
Get full text

Pembrolizumab plus best supportive care versus placebo plus best supportive care as second-line therapy in patients in Asia with advanced hepatocellular carcinoma (HCC): Phase 3 KEYNOTE-394 study by Qin, Shukui, Chen, Zhendong, Fang, Weijia, Ren, Zhenggang, Xu, Ruocai, Ryoo, Baek-Yeol, Meng, Zhiqiang, Bai, Yuxian, Chen, Xiaoming, Liu, Xiufeng, Xiao, Juxiang, Ho, Gwo Fuang, Mao, Yimin, Ye, Xing, Ying, Jieer, Li, Jianfeng, Zhong, Wen Yan, Zhou, Yu, Siegel, Abby B., Hao, Chunyi

“…Abstract only 383 Background: The anti–PD-1 antibody pembro showed efficacy and manageable safety in the global phase 2 KEYNOTE-224 and phase 3 KEYNOTE-240…”
Get full text

Final overall survival for the phase III KN177 study: Pembrolizumab versus chemotherapy in microsatellite instability-high/mismatch repair deficient (MSI-H/dMMR) metastatic colorectal cancer (mCRC) by Andre, Thierry, Shiu, Kai-Keen, Kim, Tae Won, Jensen, Benny Vittrup, Jensen, Lars Henrik, Punt, Cornelis J. A., Smith, Denis Michel, Garcia-Carbonero, Rocio, Alcaide, Julia, Gibbs, Peter, De La Fouchardiere, Christelle, Rivera, Fernando, Elez, Elena, Bendell, Johanna C., Le, Dung T., Yoshino, Takayuki, Zhong, Wen Yan, Fogelman, David R., Marinello, Patricia, Diaz, Luis A.

“…Abstract only 3500 Background: In the phase III, randomized open-label KEYNOTE-177 (NCT02563002) study 1L pembrolizumab (pembro) versus chemotherapy (chemo)…”
Get full text

Organic Matters and Lipid Biomarkers in Surface Sediments from the Northern South China Sea： Origins and Transport by Xu, Weihai, Yan, Wen, Chen, Zhong, Chen, Han, Huang, Weixia, Lin, Tian

“…In this study, content and distribution of organic matters （OM） and lipid biomarkers in surface sediments from northern South China Sea （SCS） were identified…”
Get full text

Clay mineral distribution in surface sediments of the South China Sea and its significance for in sediment sources and transport by Liu, Jianguo, Chen, Muhong, Chen, Zhong, Yan, Wen

“…Clay minerals of surface sediments in the South China Sea （SCS） are analyzed with X-ray diffraction, and their transport is explored with a grain size trend…”
Get full text

Mn Diffusion at Early Stage of Intercritical Annealing of 5Mn Steel by LUO, Xi-nan, ZHONG, Xiao-yan, LUO, Hai-wen, ZHOU, Hui-hua, WANG, Cun-yu, SHI, Jie

“…Mn distribution and austenite morphology at the early stage of intercritical annealing of 5Mn steel were investigated. It was experimentally demonstrated that…”
Get full text

Massive hemoptysis and hemothorax： a rare but fatal complication of intralobar sequestration by Wang, Hong-Wei, Lu, Jiang-Yang, Sun, Jun-Zhong, Xiao, Yan, Wen, Bo

“…Intralobar sequestration （ILS） is an uncommon abnormality that accounts for 75% of all pulmonary sequestrations. Over the years there have been several reports…”
Get full text

Genetic affinity between the Kam-Sui speaking Chadong and Mulam people by DENG, Qiong-Ying, WANG, Chuan-Chao, WANG, Xiao-Qing, WANG, Ling-Xiang, WANG, Zhong-Yan, WU, Wen-Jun, LI, Hui

“…The origins of Kam-Sui speaking Chadong and Mulam people have been controversial subjects in ethnic history studies and other related fields. Here, we studied…”
Get full text

Inhibitory effects of tetrandrine on the Na^＋ channel of human atrial fibrillation myocardium by Chen, Li, Li, Qi-yong, Yang, Yan, Li, Zhong-wen, Zeng, Xiao-rong

“…Aim： Tetrandrine （Tet） is a Ca^2＋ channel blocker and has antiarrhythmic effects. Less information exists with regard to the mechanisms underlying its…”
Get full text

Rapid Identification and Subtyping of Enterobacter cloacae Clinical Isolates Using Peptide Mass Fingerprinting by Wang, Yi Qian, Xiao, Di, Li, Juan, Zhang, Hui Fang, Fu, Bao Qing, Wang, Xiao Ling, Ai, Xiao Man, Xiong, Yan Wen, Zhang, Jian Zhong, Ye, Chang Yun

“…To establish a domestic database of Enterobacteria cloacae (E. cloacae), and improve the identification efficiency using peptide mass fingerprinting. Peptide…”
Get more information

Analysis Methods of SrTiO3 Ceramic＇s Electricity Performance by HU Yan CHEN Wen ZHONG Luo

“…The effect of oxidizing-heat-treatment conditions on the electricity performance of doped SrTiO3 ceramic is analyzed by using the theory of grey neural…”
Get full text

Hydrosilylation of olefins over rhodium complex anchored over thioether-functionalized MCM-41 by Zha, Lig Fang, Yang, Wei Sen, Hao, Wen Yan, Cai, Ming Zhong

“…The hydrosilylation of alkenes with triethoxysilane has been achieved at 120 C in the presence of 0.01 mol%of thioetherfunctionalized MCM-41 anchored rhodium…”
Get full text

Dynamic energy spectrum and energy deposition in solid target by intense pulsed ion beams by Yu, Xiao, Liu, Zheng, Shen, Jie, Isakova, Yu I., Zhong, Hao-Wen, Zhang, Jie, Yan, Sha, Zhang, Gao-Long, Zhang, Xiao-Fu, Le, Xiao-Yun

“…A method for analyzing the dynamic energy spectrum of intense pulsed ion beam (IPIB) was proposed. Its influence on beam energy deposition in metal target was…”
Get full text

Effect of Thermomechanical Controlled Processing Parameters on Microstructure and Properties of Q460q Steel by WANG, Lei, GAO, Cai-ru, WANG, Yan-feng, JIN, Wen-zhong, ZHAO, De-wen, LIU, Xiang-hua

“…With tensile test, impact test, and optical microscopy, the effect of thermomechanical controlled processing （TMCP） parameters on the microstructure and…”
Get full text

Omethoate-lnduced Changes of （＋）-δ-Cadinene Synthase Activity and Gossypol Content in Cotton Seedlings by YANG Wen-ling SHI Xue-yan ZHONG Li LIANG Pei SONG Dun-lun GAO Xi-wu

“…The gene expression and activity of （＋）-δ-cadinene synthase during cotton development and in response to stress, as well as the spatial and temporal pattern of…”
Get full text

Value of a virtual hepatic segment model in assisting in the ultrasonic localization of intrahepatic lesions by Cheng, Guo, Guo, Yan-li, Zhong, Chun-yan, Tan, Li-wen, Zhang, Shao-xiang

“…Background During scanning of the right hypochondrium and right intercostal regions with an ultrasonic transducer,several ultrasonic images of oblique sections…”
Get full text

SDG714 Regulates Specific Gene Expression and Consequently Affects Plant Growth via H3K9 Dimethylation by Ding, Bo, Zhu, Yan, Bu, Zhong-Yuan, Shen, Wen-Hui, Yu, Yu, Dong, Ai-Wu

“…Histone lysine methylation is known to be involved in the epigenetic regulation of gene expression in all eukaryotes including plants. Here we show that the…”
Get full text