Search Results - "Zhong, Wang Zhen"

Cesium Amide‐Catalyzed Selective Deuteration of Benzylic C‐H Bonds with D2 and Application for Tritiation of Pharmaceuticals by Du, Hui‐Zhen, Fan, Jun‐Zhen, Wang, Zhong‐Zhen, Strotman, Neil A., Yang, Haifeng, Guan, Bing‐Tao

“…Hydrogen isotope exchange (HIE) represents one of the most attractive labeling methods to synthesize deuterium‐ and tritium‐labeled compounds. Catalytic HIE…”
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Discovery of C-9 Modified Berberine Derivatives as Novel Lipid-Lowering Agents by Li, Dong-Dong, Yu, Pan, Xu, Hui, Wang, Zhen-Zhong, Xiao, Wei, Zhao, Lin-Guo

“…Berberine (BBR), a kind of quaternary ammonium benzylisoquinoline alkaloids with multiple pharmacological activities, has been regarded as a promising…”
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Diterpene ginkgolides protect against cerebral ischemia/reperfusion damage in rats by activating Nrf2 and CREB through PI3K/Akt signaling by Zhang, Wen, Song, Jun-ke, Yan, Rong, Li, Li, Xiao, Zhi-yong, Zhou, Wen-xia, Wang, Zhen-zhong, Xiao, Wei, Du, Guan-hua

“…Diterpene ginkgolides meglumine injection (DGMI) is a therapeutic extract of Ginkgo biloba L, which has been used for the treatment of cerebral ischemic stroke…”
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Artesunate induces apoptosis of bladder cancer cells by miR-16 regulation of COX-2 expression by Zuo, Wei, Wang, Zhen-Zhong, Xue, Jun

“…Bladder cancer is the most common malignant tumor of the urinary tract and remains one of the major causes of cancer death worldwide. In this study, we…”
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Neuroprotective effects of Ginkgolide B in focal cerebral ischemia through selective activation of prostaglandin E2 receptor EP4 and the downstream transactivation of epidermal growth factor receptor by Yang, Hao, Li, Gui‐Ping, Liu, Qiu, Zong, Shao‐Bo, Li, Liang, Xu, Zhi‐Liang, Zhou, Jun, Cao, Liang, Wang, Zhen‐Zhong, Zhang, Quan‐Chang, Li, Ming, Fan, Qi‐Ru, Hu, Han‐Fei, Xiao, Wei

“…The present study was undertaken to identify whether prostaglandin E2 receptor is the potential receptor/binding site for Ginkgolide A, Ginkgolide B,…”
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Identification of the absorptive constituents and their metabolites in vivo of Ziziphi Spinosae Semen by UPLC–ESI–Q‐TOF–MS/MS by Shang, Jing, Chen, Xia‐Lin, Li, Lu, Zhang, Hong, Yang, Li, Yang, Biao, Cao, Liang, Wang, Zhen‐Zhong, Xiao, Wei

“…In this research, ultra‐performance liquid chromatography coupled with electrospray ionization quadrupole time‐of‐flight mass spectrometry…”
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Illiciumlignans G-O from the leaves of Illicium dunnianum and their anti-inflammatory activities by Ma, Sen-Ju, Li, Hai-Bo, Li, Ting, Su, Zhen-Zhen, Wang, Zhen-Zhong, Yao, Xin-Sheng, Xiao, Wei, Yu, Yang

“…Phytochemical investigations on the dry leaves of have led to the isolation of 24 lignans. Illiciumlignans G-K (1-5) were five undescribed benzofuran lignans,…”
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One undescribed glycoside benzofuran derivative and a new p-hydroxybenzoate glycoside from the leaves of Illicium dunnianum Tutcher by He, Xiao-qing, Li, Hai-bo, Li, Ting, Chen, Xin-yin, Wang, Zhen-zhong, Yao, Xin-sheng, Xiao, Wei, Yu, Yang

“…One undescribed benzofuran derivative (illiciumphenolicacid A, 1) and one new phenolic glycoside (illiciumphenolicacid B, 2), together with six known compounds…”
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Eight new phenolic acids from the leaves of Illicium dunnianum and their osteoprotective activities by Li, Hai-Bo, Ma, Sen-Ju, Shan, Ying-Xin, Li, Ting, Wang, Zhen-Zhong, Xiao, Wei, Qiu, Zuo-Cheng, Yu, Yang

“…Eight previously unreported phenolic acids (1-8), including three new phenylpropenoid glycosides (1-3), and five undescribed shikimic acid derivatives (4-8),…”
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Two new chemical constituents from Lonicera japonica by Geng, Jian-liang, Li, Hai-bo, Liu, Wen-jun, Wang, Zhen-zhong, Ge, Wen, Xiao, Wei

“…Two new chemical constituents, japopenoid D (1), and japopenoid E (2), were isolated and identified from the flower buds of Lonicera japonica Thunb. The…”
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Improved uniformity of deposited metallic layer on hybrid micro/nano-structured Si substrates fabricated by two-step laser ablation for SERS application by Li, Long-fan, Zhou, Rui, Cui, Jing-qin, Yan, Huang-ping, Wang, Zhen-zhong

“…Surface-enhanced Raman scattering (SERS) has been widely used as an effective technique for low-concentration molecules detections in the past decades. This…”
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Two new chemical constituents from the leaves of Illicium dunnianum by Shao, Jun-Ran, Ma, Sen-Ju, Li, Ting, He, Xiao-Qing, Wang, Zhen-Zhong, Xiao, Wei, Yao, Xin-Sheng, Li, Hai-Bo, Yu, Yang

“…One new phenolic glycoside (1) and one new benzofuran derivative (2) were isolated from the leaves of Illicium dunnianum. The structures of these compounds…”
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Quality markers screening of traditional Chinese medicine prescriptions based on the multi-factor analysis strategy: Jin-Zhen oral liquid as a case by Liu, Ling-xian, Li, Hai-bo, Zhang, Jia-ying, Shi, Dan-feng, Wang, Zhen-zhong, Yao, Xin-sheng, Xiao, Wei, Yu, Yang

“…Jin-Zhen oral liquid (JZOL), a well-known traditional Chinese medicine prescription (TCMp), has extensively been used to treat acute bronchitis in children…”
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Molecular Dynamics Analysis of Binding Sites of Epidermal Growth Factor Receptor Kinase Inhibitors by Li, Dong-Dong, Wu, Ting-Ting, Yu, Pan, Wang, Zhen-Zhong, Xiao, Wei, Jiang, Yan, Zhao, Lin-Guo

“…The development of an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) is an ongoing and challenging research field. However, the…”
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The activity-integrated method for quality assessment of reduning injection by on-line DPPH-CE-DAD by Chang, Yan-xu, Liu, Jiao, Bai, Yang, Li, Jin, Liu, Er-wei, He, Jun, Jiao, Xiu-cheng, Wang, Zhen-zhong, Gao, Xiu-Mei, Zhang, Bo-li, Xiao, Wei

“…A sensitive on-line DPPH-CE-DAD method was developed and validated for both screening and determining the concentration of seven antioxidants of Reduning…”
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Metabolic profiles of Jin‐hong tablets in rats by ultra‐performance liquid chromatography coupled with quadrupole time‐of‐flight tandem mass spectrometry by Liu, Ling‐Xian, Cao, Liang, Shi, Dan‐Feng, Wang, Zhen‐Zhong, Xiao, Wei, Yao, Xin‐Sheng, Li, Hai‐Bo, Yu, Yang

“…Jin‐hong tablets (JHTs), a well‐known traditional Chinese patent medicine (TCPM), have been effectively used for the treatment of chronic superficial gastritis…”
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An open-labeled, randomized, multicenter phase IIa study of gambogic acid injection for advanced malignant tumors by Chi, Yihebali, Zhan, Xiao-kai, Yu, Hao, Xie, Guang-ru, Wang, Zhen-zhong, Xiao, Wei, Wang, Yong-gang, Xiong, Fu-xing, Hu, Jun-feng, Yang, Lin, Cui, Cheng-xu, Wang, Jin-wan

“…Gambogic acid is a pure active compound isolated from the traditional Chinese medicinal plant gamboge (Garcinia morella Desv.). Based on the preliminary…”
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Cellular pharmacokinetics and pharmacodynamics mechanisms of ginkgo diterpene lactone and its modulation of P‐glycoprotein expression in human SH‐SY5Y cells by Liu, Jing‐ying, Geng, Ting, Duan, Kun, Gao, Xia, Huang, Chao‐jie, Wang, Jia‐jia, Huang, Wen‐zhe, Huang, Lou‐sheng, Wang, Zhen‐zhong, Xiao, Wei

“…Ginkgo diterpene lactone (GDL) is the raw material for ginkgo diterpene lactone meglumine injection, which is used for treating cerebral ischemia. The aims of…”
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Fine mapping of powdery mildew resistance gene PmTm4 in wheat using comparative genomics by XIE, Jing-zhong, WANG, Li-li, WANG, Yong, ZHANG, Huai-zhi, ZHOU, Sheng-hui, WU, Qiu-hong, CHEN, Yong-xing, WANG, Zhen-zhong, WANG, Guo-xin, ZHANG, De-yun, ZHANG, Yan, HU, Tie-zhu, LIU, Zhi-yong

“…Powdery mildew,caused by Blumeria graminis f.sp.tritici,is one of the most severe wheat diseases.Mining powdery mildew resistance genes in wheat cultivars and…”
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Suppression of NF-κB signaling and P-glycoprotein function by gambogic acid synergistically potentiates adriamycin -induced apoptosis in lung cancer by Wang, Li-Hui, Yang, Jing-Yu, Yang, Sheng-Nan, Li, Yi, Ping, Guan-Fang, Hou, Yue, Cui, Wei, Wang, Zhen-Zhong, Xiao, Wei, Wu, Chun-Fu

“…Gambogic acid (GA) has been approved by the Chinese Food and Drug Administration for the treatment of lung cancer in clinical trials. However, whether GA has…”
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