Search Results - "Zhong, Mengjun"

The biomarkers of hyperprogressive disease in PD-1/PD-L1 blockage therapy by Wang, Xueping, Wang, Fang, Zhong, Mengjun, Yarden, Yosef, Fu, Liwu

“…Immune checkpoint inhibitors (ICIs), such as PD-1/PD-L1 antibodies (Abs) and anti-cytotoxic T lymphocyte antigen 4 (CTLA-4) Abs, are effective for patients…”
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2B4 costimulatory domain enhancing cytotoxic ability of anti-CD5 chimeric antigen receptor engineered natural killer cells against T cell malignancies by Xu, Yingxi, Liu, Qian, Zhong, Mengjun, Wang, Zhenzhen, Chen, Zhaoqi, Zhang, Yu, Xing, Haiyan, Tian, Zheng, Tang, Kejing, Liao, Xiaolong, Rao, Qing, Wang, Min, Wang, Jianxiang

“…Chimeric antigen receptor engineered T cells (CAR-T) have demonstrated extraordinary efficacy in B cell malignancy therapy and have been approved by the US…”
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Bond Stress-Slip Model of BFRP Grid to ECC by Deng, Langni, Li, Taisheng, Zhong, Mengjun, Liao, Ling, Li, Hua

“…The bonding performance between a basalt fiber-reinforced composite material (BFRP) grid and an engineering cementitious composite (ECC) is the basis that…”
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A study on the three-dimensional contact quantitative analysis of coarse aggregate in steel slag asphalt mixture based on X-ray CT by Wan, Cheng, Zhong, Mengjun, Yinghao, Zhao

“…The contact points between coarse aggregates in steel slag asphalt mixture are critical areas of stress concentration and weak links in the stress transmission…”
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BET bromodomain inhibition rescues PD-1-mediated T-cell exhaustion in acute myeloid leukemia by Zhong, Mengjun, Gao, Rili, Zhao, Ruocong, Huang, Youxue, Chen, Cunte, Li, Kehan, Yu, Xibao, Nie, Dingrui, Chen, Zheng, Liu, Xin, Liu, Zhuandi, Chen, Shaohua, Lu, Yuhong, Yu, Zhi, Wang, Liang, Li, Peng, Zeng, Chengwu, Li, Yangqiu

“…Sustained expression of programmed cell death receptor-1 (PD-1) is correlated with the exhaustion of T cells, and blockade of the PD-1 pathway is an effective…”
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Visualization and monitoring information management of bridge structure health and safety early warning based on BIM by Deng, Langni, Lai, Shijin, Ma, Jinchao, Lei, Lizhen, Zhong, Mengjun, Liao, Ling, Zhou, Zheng

“…Bridge structure health assessment has become a research hotspot. However, the traditional methods lack unified integrated management of the health monitoring…”
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Efficacy and safety of CD19 CAR T constructed with a new anti-CD19 chimeric antigen receptor in relapsed or refractory acute lymphoblastic leukemia by Gu, Runxia, Liu, Fang, Zou, Dehui, Xu, Yingxi, Lu, Yang, Liu, Bingcheng, Liu, Wei, Chen, Xiaojuan, Liu, Kaiqi, Guo, Ye, Gong, Xiaoyuan, Lv, Rui, Chen, Xia, Zhou, Chunlin, Zhong, Mengjun, Wang, Huijun, Wei, Hui, Mi, Yingchang, Qiu, Lugui, Lv, Lulu, Wang, Min, Wang, Ying, Zhu, Xiaofan, Wang, Jianxiang

“…Recent evidence suggests that resistance to CD19 chimeric antigen receptor (CAR)-modified T cell therapy may be due to the presence of CD19 isoforms that lose…”
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Research on Safety Management Application of Dangerous Sources in Engineering Construction Based on BIM Technology by Peng, Lai, Liao, Ling, Zhong, Mengjun, Deng, Langni, Lai, Shijin

“…The construction industry is a high-risk industry, so many scholars have done research on how to reduce safety accidents at the construction site. However, due…”
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Reversal of ABCB1-related multidrug resistance by ERK5-IN-1 by Wang, Fang, Li, Delan, Zheng, ZongHeng, Kin Wah To, Kenneth, Chen, Zhen, Zhong, Mengjun, Su, Xiaodong, Chen, Likun, Fu, Liwu

“…Inhibition of ABC transporters is considered the most effective way to circumvent multidrug resistance (MDR). In the present study, we evaluated the MDR…”
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Targeting NRF2 uncovered an intrinsic susceptibility of acute myeloid leukemia cells to ferroptosis by Liu, Xin, Zhong, Shuxin, Qiu, Kangjie, Chen, Xi, Wu, Weiyue, Zheng, Jiamian, Liu, Yanwen, Wu, Haolong, Fan, Shiyun, Nie, Dingrui, Wang, Xianfeng, Yu, Zhi, Liao, Ziwei, Zhong, Mengjun, Li, Yangqiu, Zeng, Chengwu

“…Drug resistance and poor treatment response are major obstacles to the effective treatment of acute myeloid leukemia (AML). A deeper understanding of the…”
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BRD4 inhibitor reduces exhaustion and blocks terminal differentiation in CAR-T cells by modulating BATF and EGR1 by Sui, Songnan, Zhong, Mengjun, Zhong, Shuxin, Peng, Xueting, Mao, Lipeng, Chen, Cunte, Zeng, Chengwu, Luo, Oscar Junhong, Li, Yangqiu

“…Exhaustion is a key factor that influences the efficacy of chimeric antigen receptor T (CAR-T) cells. Our previous study demonstrated that a bromodomain…”
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Study on the Flexural Fatigue Performance of CFRP-OFBG Plate Reinforced Damaged Steel Beams by Deng, Langni, Zhong, Mengjun, Liu, Yang, Liao, Ling, Lai, Shijin, Lei, Lizhen, Zhou, Zheng

“…This paper studies the flexural fatigue performance of damaged steel beams strengthened by carbon fiber reinforced plastic-optical fiber bragg grating…”
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High expression of LOC541471, GDAP1, SOD1, and STK25 is associated with poor overall survival of patients with acute myeloid leukemia by Yu, Xibao, Chen, Cunte, Hu, Yanyun, Li, Kehan, Zhang, Yikai, Chen, Zheng, Nie, Dingrui, Gao, Rili, Huang, Youxue, Zhong, Mengjun, Wang, Caixia, Wang, Shunqing, Zeng, Yixin, Li, Yangqiu, Zeng, Chengwu

“…Background Acute myeloid leukemia (AML) is an aggressive heterogeneous hematological malignancy with remarkably heterogeneous outcomes. This study aimed to…”
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Correction to: BET bromodomain inhibition rescues PD-1-mediated T-cell exhaustion in acute myeloid leukemia by Zhong, Mengjun, Gao, Rili, Zhao, Ruocong, Huang, Youxue, Chen, Cunte, Li, Kehan, Yu, Xibao, Nie, Dingrui, Chen, Zheng, Liu, Xin, Liu, Zhuandi, Chen, Shaohua, Lu, Yuhong, Yu, Zhi, Wang, Liang, Li, Peng, Zeng, Chengwu, Li, Yangqiu

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Investigation of Flexural Fatigue Behavior of Concrete Beams Reinforced with Intelligent CFRP-OFBG Plates by Zhong, Mengjun, Huang, Xiaoxia, Xie, Hong, Liao, Ling, Liu, Yang, Deng, Langni, Lai, Shijin

“…The fatigue properties of concrete beams reinforced with carbon fiber-reinforced polymer-optical fiber Bragg grating (CFRP-OFBG) plates under three-point…”
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Lower BCL11B expression is associated with adverse clinical outcome for patients with myelodysplastic syndrome by Huang, Xin, Chen, Cunte, Zhong, Mengjun, Geng, Suxia, Zhao, Yujie, Li, Minming, Deng, Chenxin, Zeng, Lingji, Wu, Ping, Lu, Zesheng, Weng, Jianyu, Du, Xin, Li, Yangqiu

“…Abstract Myelodysplastic syndrome (MDS) is an aggressive and genetically heterogeneous disease with poor prognosis. Cellular immune disorder is a common…”
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Culture and application of conditionally reprogrammed primary tumor cells by Zhong, Mengjun, Fu, Liwu

“…Abstract Cancer is still a major public-health problem that threatens human life worldwide and further study needs to be carried out in the basic and…”
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Anticancer effects of disulfiram in T‐cell malignancies through NPL4‐mediated ubiquitin–proteasome pathway by Chen, Cunte, Nie, Dingrui, Huang, Youxue, Yu, Xibao, Chen, Zheng, Zhong, Mengjun, Liu, Xin, Wang, Xianfeng, Sui, Songnan, Liu, Zhuandi, Tan, Jiaxiong, Yu, Zhi, Li, Yangqiu, Zeng, Chengwu

“…T‐cell malignancies, including T‐cell acute lymphoblastic leukemia (T‐ALL) and T‐cell lymphoma (TCL), are characterized by inferior treatment effects, high…”
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3115 – SINGLE-CELL RNA SEQUECING REVEALS BRD4 INHIBITOR REDUCING CAR-T CELL EXHAUSTION BY MODULATING BATF AND EGR1 by Sui, Songnan, Zhong, Mengjun, Zhong, Shuxin, Zeng, Chengwu, Luo, Oscar Junhong, Li, Yangqiu

“…Exhaustion is a key factor impaired therapeutic efficacy of CAR-T cells. This study aims to uncover the potential mechanism by which bromodomain protein 4…”
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Overexpression of CASP1 triggers acute promyelocytic leukemia cell pyroptosis and differentiation by Yu, Xibao, Liu, Xin, Liu, Xuan, Jin, Shuang, Zhong, Mengjun, Nie, Dingrui, Zeng, Xiangbo, Wang, Xianfeng, Tan, Jiaxiong, Li, Yangqiu, Zeng, Chengwu

“…Caspase-1 (CASP1)-mediated classical pyroptosis plays a key role in cancer development and management, however, the role of CASP1 and its regulation has not…”
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