Search Results - "Zhong, Jiuchang"

Roles of Growth Differentiation Factor 15 in Atherosclerosis and Coronary Artery Disease by Wang, Juan, Wei, Liqun, Yang, Xinchun, Zhong, Jiuchang

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Targeting Iron Metabolism and Ferroptosis as Novel Therapeutic Approaches in Cardiovascular Diseases by Chen, Yufei, Li, Xueting, Wang, Siyuan, Miao, Ran, Zhong, Jiuchang

“…Iron functions as an essential micronutrient and participates in normal physiological and biochemical processes in the cardiovascular system. Ferroptosis is a…”
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Ferritinophagy activation and sideroflexin1-dependent mitochondria iron overload is involved in apelin-13-induced cardiomyocytes hypertrophy by Tang, Mingzhu, Huang, Zhen, Luo, Xuling, Liu, Meiqing, Wang, Lingzhi, Qi, Zhihao, Huang, Shifang, Zhong, Jiuchang, Chen, Jian-Xiong, Li, Lanfang, Wu, Di, Chen, Linxi

“…Excess iron accumulation and cardiac oxidative stress have been shown as important mediators of cardiac hypertrophy, whereas it remains largely elusive about…”
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Targeting the elabela/apelin-apelin receptor axis as a novel therapeutic approach for hypertension by Song, Jiawei, Tang, Jianqiong, Zhang, Zhenzhou, Liu, Ying, Zhong, Jiuchang

“…Abstract Hypertension is the leading risk factor for global mortality and morbidity and those with hypertension are more likely to develop severe symptoms in…”
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Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction by JIUCHANG ZHONG, BASU, Ratnadeep, OUDIT, Gavin Y, GUO, Danny, CHOW, Fung L, BYRNS, Simon, SCHUSTER, Manfred, LOIBNER, Hans, WANG, Xiu-Hua, PENNINGER, Josef M, KASSIRI, Zamaneh

“…Angiotensin-converting enzyme 2 (ACE2) is a pleiotropic monocarboxypeptidase capable of metabolizing several peptide substrates. We hypothesized that ACE2 is a…”
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Gut-dependent microbial translocation induces inflammation and cardiovascular events after ST-elevation myocardial infarction by Zhou, Xin, Li, Jing, Guo, Junli, Geng, Bin, Ji, Wenjie, Zhao, Qian, Li, Jinlong, Liu, Xinlin, Liu, Junxiang, Guo, Zhaozeng, Cai, Wei, Ma, Yongqiang, Ren, Dong, Miao, Jun, Chen, Shaobo, Zhang, Zhuoli, Chen, Junru, Zhong, Jiuchang, Liu, Wenbin, Zou, Minghui, Li, Yuming, Cai, Jun

“…Post-infarction cardiovascular remodeling and heart failure are the leading cause of myocardial infarction (MI)-driven death during the past decades…”
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miR-17-3p Contributes to Exercise-Induced Cardiac Growth and Protects against Myocardial Ischemia-Reperfusion Injury by Shi, Jing, Bei, Yihua, Kong, Xiangqing, Liu, Xiaojun, Lei, Zhiyong, Xu, Tianzhao, Wang, Hui, Xuan, Qinkao, Chen, Ping, Xu, Jiahong, Che, Lin, Liu, Hui, Zhong, Jiuchang, Sluijter, Joost Pg, Li, Xinli, Rosenzweig, Anthony, Xiao, Junjie

“…Limited microRNAs (miRNAs, miRs) have been reported to be necessary for exercise-induced cardiac growth and essential for protection against pathological…”
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Altered synthesis of genes associated with short-chain fatty acids in the gut of patients with atrial fibrillation by Zhang, Jing, Zuo, Kun, Fang, Chen, Yin, Xiandong, Liu, Xiaoqing, Zhong, Jiuchang, Li, Kuibao, Li, Jing, Xu, Li, Yang, Xinchun

“…The gut microbiota provides health benefits in humans by producing short-chain fatty acids (SCFAs), whose deficiency causes multiple disorders and inflammatory…”
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Prevention of Angiotensin II–Mediated Renal Oxidative Stress, Inflammation, and Fibrosis by Angiotensin-Converting Enzyme 2 by Zhong, JiuChang, Guo, Danny, Chen, Christopher B, Wang, Wang, Schuster, Manfred, Loibner, Hans, Penninger, Josef M, Scholey, James W, Kassiri, Zamaneh, Oudit, Gavin Y

“…Angiotensin-converting enzyme 2 (ACE2) is a monocarboxypeptidase capable of metabolizing angiotensin (Ang) II into Ang 1 to 7. We hypothesized that ACE2 is a…”
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Profile of gut flora in hypertensive patients with insufficient sleep duration by Jiao, Jie, Dong, Ying, Wang, Pan, Zuo, Kun, Han, Chunming, Cai, Jun, Zhong, Jiuchang, Yang, Xinchun, Li, Jing

“…Recently, the contribution of both insufficient sleep duration and gut microbiome dysbiosis to hypertension (HTN) have been revealed, yet the profile of gut…”
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Loss of Angiotensin-Converting Enzyme-2 Exacerbates Diabetic Cardiovascular Complications and Leads to Systolic and Vascular Dysfunction: A Critical Role of the Angiotensin II/AT1 Receptor Axis by Patel, Vaibhav B, Bodiga, Sreedhar, Basu, Ratnadeep, Das, Subhash K, Wang, Wang, Wang, Zuocheng, Lo, Jennifer, Grant, Maria B, Zhong, JiuChang, Kassiri, Zamaneh, Oudit, Gavin Y

“…RATIONALE:Diabetic cardiovascular complications are reaching epidemic proportions. Angiotensin-converting enzyme-2 (ACE2) is a negative regulator of the…”
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Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy by OUDIT, Gavin Y, LIU, George C, HERZENBERG, Andrew M, KASSIRI, Zamaneh, SCHOLEY, James W, JIUCHANG ZHONG, BASU, Ratnadeep, CHOW, Fung L, ZHOU, Joyce, LOIBNER, Hans, JANZEK, Evelyne, SCHUSTER, Manfred, PENNINGER, Josef M

“…Human Recombinant ACE2 Reduces the Progression of Diabetic Nephropathy Gavin Y. Oudit 1 , 2 , George C. Liu 3 , JiuChang Zhong 1 , 2 , Ratnadeep Basu 1 , 2 ,…”
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Inhibition of miR-155 Protects Against LPS-induced Cardiac Dysfunction and Apoptosis in Mice by Wang, Hui, Bei, Yihua, Huang, Peipei, Zhou, Qiulian, Shi, Jing, Sun, Qi, Zhong, Jiuchang, Li, Xinli, Kong, Xiangqing, Xiao, Junjie

“…Sepsis-induced myocardial dysfunction represents a major cause of death in intensive care units. Dysregulated microRNAs (miR)-155 has been implicated in…”
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Association between circulating levels of ACE2-Ang-(1–7)-MAS axis and ACE2 gene polymorphisms in hypertensive patients by Liu, Dan, Chen, Yongyue, Zhang, Ping, Zhong, Jiuchang, Jin, Lijun, Zhang, Caojin, Lin, Shuguang, Wu, Shulin, Yu, Huimin

“…The angiotensin-converting enzyme 2-angiotensin-(1-7)-MAS axis (ACE2-Ang-[1-7]-MAS axis) plays an important role in the control of blood pressure. Some…”
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PAGln, an Atrial Fibrillation-Linked Gut Microbial Metabolite, Acts as a Promoter of Atrial Myocyte Injury by Fang, Chen, Zuo, Kun, Jiao, Kaicheng, Zhu, Xiaoming, Fu, Yuan, Zhong, Jiuchang, Xu, Li, Yang, Xinchun

“…Phenylacetylglutamine (PAGln), a gut microbiota (GM)-derived metabolite, is associated with cardiovascular disease. Studies have shown that disordered GM…”
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Hsa_circ_0046159 is involved in the development of chronic thromboembolic pulmonary hypertension by Miao, Ran, Gong, Juanni, Zhang, Chunyang, Wang, Ying, Guo, Xiaojuan, Li, Jifeng, Yang, Suqiao, Kuang, Tuguang, Zhong, Jiuchang, Feng, Huasong

“…The present study was performed to screen for potential molecular biomarkers and to assess the underlying mechanisms of chronic thromboembolic pulmonary…”
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Increased plasma ACE2 concentration does not mean increased risk of SARS-CoV-2 infection and increased fatality rate of COVID-19 by Li, Xueting, Liu, Ying, Song, Juanjuan, Zhong, Jiuchang

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Cardioprotective Effects Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin 1-7 in Experimental Heart Failure in Angiotensin-Converting Enzyme 2–Null Mice by Patel, Vaibhav B, Bodiga, Sreedhar, Fan, Dong, Das, Subhash K, Wang, Zuocheng, Wang, Wang, Basu, Ratnadeep, Zhong, JiuChang, Kassiri, Zamaneh, Oudit, Gavin Y

“…Loss of angiotensin (Ang)-converting enzyme 2 (ACE2) and inability to metabolize Ang II to Ang 1-7 perpetuate the actions of Ang II after biomechanical stress…”
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Diagnostic value of miRNA expression and right ventricular echocardiographic functional parameters for chronic thromboembolic pulmonary hypertension with right ventricular dysfunction and injury by Miao, Ran, Gong, Juanni, Guo, Xiaojuan, Guo, Dichen, Zhang, Xinyuan, Hu, Huimin, Zhong, Jiuchang, Yang, Yuanhua, Li, Yidan

“…We aimed to establish the relationships between the expression of microRNAs (miRNAs) and echocardiographic right ventricular (RV) function parameters, and to…”
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Circulating exosomal lncRNAs in patients with chronic coronary syndromes by Zheng, Meili, Han, Ruijuan, Yuan, Wen, Chi, Hongjie, Zhang, Yeping, Sun, Kai, Zhong, Jiuchang, Liu, Xiaoyan, Yang, Xinchun

“…The concept of chronic coronary syndrome (CCS) was first presented at the European Society of Cardiology Meeting in 2019. However, the roles of exosomal…”
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