Search Results - "Zhong, Hongyu"
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1
Cobalt-catalyzed asymmetric hydrogenation of enamides enabled by single-electron reduction
Published in Science (American Association for the Advancement of Science) (25-05-2018)“…Identifying catalyst activation modes that exploit one-electron chemistry and overcome associated deactivation pathways will be transformative for developing…”
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2
Visible light enables catalytic formation of weak chemical bonds with molecular hydrogen
Published in Nature chemistry (01-10-2021)“…The synthesis of weak chemical bonds at or near thermodynamic potential is a fundamental challenge in chemistry, with applications ranging from catalysis to…”
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3
Regio- and Diastereoselective Iron-Catalyzed [4+4]-Cycloaddition of 1,3-Dienes
Published in Journal of the American Chemical Society (29-05-2019)“…A family of single-component iron precatalysts for the [4+4]-cyclodimerization and intermolecular cross-[4+4]-cycloaddition of monosubstituted 1,3-dienes is…”
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4
Neonatal curcumin treatment restores hippocampal neurogenesis and improves autism-related behaviors in a mouse model of autism
Published in Psychopharmacology (01-12-2020)“…Rationale Autism spectrum disorders (ASDs) are highly prevalent neurodevelopmental disorders characterized by deficits in social communication and interaction,…”
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5
Catalytic Hydrogenation of a Manganese(V) Nitride to Ammonia
Published in Journal of the American Chemical Society (20-05-2020)“…The catalytic hydrogenation of a metal nitride to produce free ammonia using a rhodium hydride catalyst that promotes H2 activation and hydrogen-atom transfer…”
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6
Iron-Mediated Coupling of Carbon Dioxide and Ethylene: Macrocyclic Metallalactones Enable Access to Various Carboxylates
Published in Journal of the American Chemical Society (19-09-2018)“…Treatment of (iPrPDI)Fe(N2)2 (iPrPDI, 2,6-(2,6-iPr2C6H3NCMe)2C5H3N) with CO2 and ethylene resulted in the formation of a homologous series of saturated and…”
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7
Synthesis, Electronic Structure, and Reactivity of a Planar Four‐Coordinate, Cobalt–Imido Complex
Published in Angewandte Chemie (International ed.) (21-06-2021)“…A four‐coordinate cobalt–imido complex, (tBumPNP)Co=NMes (tBumPNP=modified PNP pincer ligand) has been synthesized from addition of 2,4,6‐trimethylphenylazide…”
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8
Skeletal metalation of lactams through a carbonyl-to-nickel-exchange logic
Published in Nature communications (29-08-2023)“…Classical metalation reactions such as the metal-halogen exchange have had a transformative impact on organic synthesis owing to their broad applicability in…”
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9
Direct reprogramming of fibroblasts into neural stem cells by single non-neural progenitor transcription factor Ptf1a
Published in Nature communications (20-07-2018)“…Induced neural stem cells (iNSCs) reprogrammed from somatic cells have great potentials in cell replacement therapies and in vitro modeling of neural diseases…”
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10
Synthesis and Reactivity of Organometallic Intermediates Relevant to Cobalt‐Catalyzed Hydroformylation
Published in Angewandte Chemie International Edition (02-06-2020)“…Intermediates relevant to cobalt‐catalyzed alkene hydroformylation have been isolated and evaluated in fundamental organometallic transformations relevant to…”
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11
Upregulation of Endothelial DKK1 (Dickkopf 1) Promotes the Development of Pulmonary Hypertension Through the Sp1 (Specificity Protein 1)/SHMT2 (Serine Hydroxymethyltransferase 2) Pathway
Published in Hypertension (Dallas, Tex. 1979) (01-05-2022)“…Pulmonary hypertension (PH) is a cancer-like proliferative disease, which has no curative treatment options. The dysfunction of pulmonary artery endothelial…”
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12
Diastereoselective B(C6F5)3‑Catalyzed Reductive Carbocyclization of Unsaturated Carbohydrates
Published in Organic letters (19-08-2016)“…A B(C6F5)3-catalyzed method for the selective conversion of unsaturated carbohydrates to cyclopentanes and cyclopropanes is disclosed. Catalyst activation of…”
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13
Loss of liver X receptor β in astrocytes leads to anxiety-like behaviors via regulating synaptic transmission in the medial prefrontal cortex in mice
Published in Molecular psychiatry (01-11-2021)“…Astrocytes are integral components of synaptic transmission, and their dysfunction leads to neuropsychiatric disorders such as anxiety and depression. Liver X…”
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14
Oxidative Addition of Dihydrogen, Boron Compounds, and Aryl Halides to a Cobalt(I) Cation Supported by a Strong-Field Pincer Ligand
Published in Organometallics (11-03-2019)“…Cationic cobalt(I) dinitrogen complexes with a strong-field tridentate pincer ligand were prepared, and the oxidative addition of polar and nonpolar bonds was…”
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15
The Liver X Receptor Agonist TO901317 Ameliorates Behavioral Deficits in Two Mouse Models of Autism
Published in Frontiers in cellular neuroscience (14-05-2019)“…Autism spectrum disorder (ASD) is a developmental disability characterized by social deficits and repetitive stereotyped behaviors. There are currently no…”
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16
Human amniotic epithelial cell transplantation promotes neurogenesis and ameliorates social deficits in BTBR mice
Published in Stem cell research & therapy (31-05-2019)“…Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impairments in social interactions and communication and stereotypical…”
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17
Novel diagnostic indicators for acute angle closure secondary to lens subluxation based on anterior segment and lens parameters
Published in Heliyon (15-02-2024)“…Purpose: To explore stable and sensitive indicators for clinical diagnosis of acute angle closure (AAC) secondary to lens subluxation (LS) through quantitative…”
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18
Efficacy of a New Non-drug Acne Therapy: Aloe Vera Gel Combined With Ultrasound and Soft Mask for the Treatment of Mild to Severe Facial Acne
Published in Frontiers in medicine (21-05-2021)“…Acne is a chronic disorder that affects almost 80% of adolescents and young adults, causing psychological and emotional distress. However, the current…”
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19
Development and preliminary application of a quadruplex real-time PCR assay for differential detection of porcine circovirus 1-4 in Chengdu, China
Published in Frontiers in veterinary science (30-04-2024)“…Porcine circovirus (PCV) typically causes severe immune suppression in pigs, leading to mixed clinical infections with various pathogens that can cause…”
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20
Abnormal Cerebellar Development Is Involved in Dystonia-Like Behaviors and Motor Dysfunction of Autistic BTBR Mice
Published in Frontiers in cell and developmental biology (07-04-2020)“…Motor control and learning impairments are common complications in individuals with autism spectrum disorder (ASD). Abnormal cerebellar development during…”
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