Search Results - "Zhong, Guisheng"

Actin, Spectrin, and Associated Proteins Form a Periodic Cytoskeletal Structure in Axons by Xu, Ke, Zhong, Guisheng, Zhuang, Xiaowei

“…Actin and spectrin play important roles in neurons, but their organization in axons and dendrites remains unclear. We used stochastic optical reconstruction…”
Get full text

Ubiquitin ligase MARCH5 localizes to peroxisomes to regulate pexophagy by Zheng, Jun, Chen, Xi, Liu, Qiang, Zhong, Guisheng, Zhuang, Min

“…Mitochondria and peroxisomes are independent but functionally closely related organelles. A few proteins have been characterized as dual-organelle locating…”
Get full text

Developmental mechanism of the periodic membrane skeleton in axons by Zhong, Guisheng, He, Jiang, Zhou, Ruobo, Lorenzo, Damaris, Babcock, Hazen P, Bennett, Vann, Zhuang, Xiaowei

“…Actin, spectrin, and associated molecules form a periodic sub-membrane lattice structure in axons. How this membrane skeleton is developed and why it…”
Get full text

AAV-ie enables safe and efficient gene transfer to inner ear cells by Tan, Fangzhi, Chu, Cenfeng, Qi, Jieyu, Li, Wenyan, You, Dan, Li, Ke, Chen, Xin, Zhao, Weidong, Cheng, Cheng, Liu, Xiaoyi, Qiao, Yunbo, Su, Bing, He, Shuijin, Zhong, Chao, Li, Huawei, Chai, Renjie, Zhong, Guisheng

“…Hearing loss is the most common sensory disorder. While gene therapy has emerged as a promising treatment of inherited diseases like hearing loss, it is…”
Get full text

Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes by Shim, Sang-Hee, Xia, Chenglong, Zhong, Guisheng, Babcock, Hazen P, Vaughan, Joshua C, Huang, Bo, Wang, Xun, Xu, Cheng, Bi, Guo-Qiang, Zhuang, Xiaowei

“…Imaging membranes in live cells with nanometer-scale resolution promises to reveal ultrastructural dynamics of organelles that are essential for cellular…”
Get full text

The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation by Zhang, Wenjie, Zhangyuan, Guangyan, Wang, Fei, Jin, Kangpeng, Shen, Haiyuan, Zhang, Liansheng, Yuan, Xiang, Wang, Jincheng, Zhang, Haitian, Yu, Weiwei, Huang, Ruyi, Xu, Xiaoliang, Yin, Yin, Zhong, Guisheng, Lin, Anning, Sun, Beicheng

“…Chronic inflammation plays a central role in hepatocellular carcinoma (HCC), but the contribution of hepatocytes to tumor-associated inflammation is not clear…”
Get full text

Laser Shock Peening: Fundamentals and Mechanisms of Metallic Material Wear Resistance Improvement by Cao, Xiaodie, Wu, Jiali, Zhong, Guisheng, Wu, Jiajun, Chen, Xinhui

“…With the rapid development of the advanced manufacturing industry, equipment requirements are becoming increasingly stringent. Since metallic materials often…”
Get full text

Organized cannabinoid receptor distribution in neurons revealed by super-resolution fluorescence imaging by Li, Hui, Yang, Jie, Tian, Cuiping, Diao, Min, Wang, Quan, Zhao, Simeng, Li, Shanshan, Tan, Fangzhi, Hua, Tian, Qin, Ya, Lin, Chao-Po, Deska-Gauthier, Dylan, Thompson, Garth J., Zhang, Ying, Shui, Wenqing, Liu, Zhi-Jie, Wang, Tong, Zhong, Guisheng

“…G-protein-coupled receptors (GPCRs) play important roles in cellular functions. However, their intracellular organization is largely unknown. Through…”
Get full text

Structural basis for CD97 recognition of the decay-accelerating factor CD55 suggests mechanosensitive activation of adhesion GPCRs by Niu, Minghui, Xu, Shengzhao, Yang, Jie, Yao, Deqiang, Li, Na, Yan, Jie, Zhong, Guisheng, Song, Gaojie

“…The adhesion G protein–coupled receptor CD97 and its ligand complement decay-accelerating factor CD55 are important binding partners in the human immune…”
Get full text

In Mice Lacking V2a Interneurons, Gait Depends on Speed of Locomotion by Crone, Steven A, Zhong, Guisheng, Harris-Warrick, Ronald, Sharma, Kamal

“…Many animals are capable of changing gait with speed of locomotion. The neural basis of gait control and its dependence on speed are not fully understood. Mice…”
Get full text

Structural plasticity of actin-spectrin membrane skeleton and functional role of actin and spectrin in axon degeneration by Wang, Guiping, Simon, David J, Wu, Zhuhao, Belsky, Deanna M, Heller, Evan, O'Rourke, Melanie K, Hertz, Nicholas T, Molina, Henrik, Zhong, Guisheng, Tessier-Lavigne, Marc, Zhuang, Xiaowei

“…Axon degeneration sculpts neuronal connectivity patterns during development and is an early hallmark of several adult-onset neurodegenerative disorders…”
Get full text

A PIK3C3-ankyrin-B-dynactin pathway promotes axonal growth and multiorganelle transport by Lorenzo, Damaris Nadia, Badea, Alexandra, Davis, Jonathan, Hostettler, Janell, He, Jiang, Zhong, Guisheng, Zhuang, Xiaowei, Bennett, Vann

“…Axon growth requires long-range transport of organelles, but how these cargoes recruit their motors and how their traffic is regulated are not fully resolved…”
Get full text

Precise regulation of the multicolor spectrum of carbon dots based on the bionic leaf vein ultrasonic microreactor by Rao, Longshi, Sun, Bin, Liu, Yang, Zhang, Qing, Zhong, Guisheng, Wen, Mingfu, Zhang, Jiayang, Fu, Ting, Niu, Xiaodong

“…Carbon dots (CDs) are a fascinating new type of fluorescent carbon nanomaterial with excellent photoelectric properties. However, preparing long-wavelength and…”
Get full text

Recent development of AAV-based gene therapies for inner ear disorders by Lan, Yiyang, Tao, Yong, Wang, Yunfeng, Ke, Junzi, Yang, Qiuxiang, Liu, Xiaoyi, Su, Bing, Wu, Yiling, Lin, Chao-Po, Zhong, Guisheng

“…Gene therapy for auditory diseases is gradually maturing. Recent progress in gene therapy treatments for genetic and acquired hearing loss has demonstrated the…”
Get full text

Structural Basis of the Diversity of Adrenergic Receptors by Qu, Lu, Zhou, Qingtong, Xu, Yueming, Guo, Yu, Chen, Xiaoyu, Yao, Deqiang, Han, Gye Won, Liu, Zhi-Jie, Stevens, Raymond C., Zhong, Guisheng, Wu, Dong, Zhao, Suwen

“…Adrenergic receptors are highly homologous while at the same time display a wide diversity of ligand and G-protein binding, and understanding this diversity is…”
Get full text

Diverse Supramolecular Nanofiber Networks Assembled by Functional Low-Complexity Domains by An, Bolin, Wang, Xinyu, Cui, Mengkui, Gui, Xinrui, Mao, Xiuhai, Liu, Yan, Li, Ke, Chu, Cenfeng, Pu, Jiahua, Ren, Susu, Wang, Yanyi, Zhong, Guisheng, Lu, Timothy K, Liu, Cong, Zhong, Chao

“…Self-assembling supramolecular nanofibers, common in the natural world, are of fundamental interest and technical importance to both nanotechnology and…”
Get full text

A cytoskeleton structure revealed by super-resolution fluorescence imaging in inner ear hair cells by Qi, Jieyu, Liu, Yan, Chu, Cenfeng, Chen, Xin, Zhu, Weijie, Shu, Yilai, He, Shuijin, Chai, Renjie, Zhong, Guisheng

Get full text

AAV-ie-K558R mediated cochlear gene therapy and hair cell regeneration by Tao, Yong, Liu, Xiaoyi, Yang, Liu, Chu, Cenfeng, Tan, Fangzhi, Yu, Zehua, Ke, Junzi, Li, Xiang, Zheng, Xiaofei, Zhao, Xingle, Qi, Jieyu, Lin, Chao-Po, Chai, Renjie, Zhong, Guisheng, Wu, Hao

“…The cochlea consists of multiple types of cells, including hair cells, supporting cells and spiral ganglion neurons, and is responsible for converting…”
Get full text

Correction: Recent development of AAV-based gene therapies for inner ear disorders by Lan, Yiyang, Tao, Yong, Wang, Yunfeng, Ke, Junzi, Yang, Qiuxiang, Liu, Xiaoyi, Su, Bing, Wu, Yiling, Lin, Chao-Po, Zhong, Guisheng

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in FcεRI-activated mast cells by Yu, Jing, Liu, Zaizhou, Liang, Yuanyuan, Luo, Feng, Zhang, Jie, Tian, Cuiping, Motzik, Alex, Zheng, Mengmeng, Kang, Jingwu, Zhong, Guisheng, Liu, Cong, Fang, Pengfei, Guo, Min, Razin, Ehud, Wang, Jing

“…Signal transduction systems enable organisms to monitor their external environments and accordingly adjust the cellular processes. In mast cells, the second…”
Get full text