Search Results - "Zhong, Caigao"

Cr(VI) induces premature senescence through ROS-mediated p53 pathway in L-02 hepatocytes by Zhang, Yujing, Zhang, Yiyuan, Zhong, Caigao, Xiao, Fang

“…Hexavalent Chromium [Cr(VI)], which can be found of various uses in industries such as metallurgy and textile dying, can cause a number of human disease…”
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Cr(VI) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway by Zhang, Yujing, Xiao, Fang, Liu, Xinmin, Liu, Kaihua, Zhou, Xiaoxin, Zhong, Caigao

“…The occupational and environmental toxicant hexavalent chromium [Cr(VI)] can cause severe damage to the liver; however, the exact mechanisms associated with…”
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Cr(VI)-Induced Autophagy Protects L-02 Hepatocytes from Apoptosis Through the ROS-AKT-mTOR Pathway by Liang, Qi, Xiao, Yuanyuan, Liu, Kaihua, Zhong, Caigao, Zeng, Ming, Xiao, Fang

“…Background/Aims: Hexavalent chromium [Cr(VI)] pollution has become a global concern for both ecosystems and human health. Our previous study revealed Cr(VI)…”
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An evaluation of the protective role of vitamin C in reactive oxygen species-induced hepatotoxicity due to hexavalent chromium in vitro and in vivo by Zhong, Xiali, Zeng, Ming, Bian, Huanfeng, Zhong, Caigao, Xiao, Fang

“…Drinking water contamination with hexavalent chromium [Cr (VI)] has become one of the most serious public health problems, thus the investigation of Cr…”
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Activation of Autophagy Protects Against ROS-Mediated Mitochondria-Dependent Apoptosis in L-02 Hepatocytes Induced by Cr(VI) by Xie, Ying, Xiao, Fang, Luo, Lei, Zhong, Caigao

“…Background: Hexavalent chromium (Cr(VI)) overdose causes hepatocellular injuries by inducing mitochondrial damage and subsequent apoptosis in animals and…”
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Mitochondrial Biogenesis in Response to Chromium (VI) Toxicity in Human Liver Cells by Zhong, Xiali, de Cássia da Silveira E Sá, Rita, Zhong, Caigao

“…Hexavalent chromium (Cr(VI)) is a ubiquitous environmental pollutant, which poses a threat to human public health. Recent studies have shown that mitochondrial…”
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CoQ10 Deficiency May Indicate Mitochondrial Dysfunction in Cr(VI) Toxicity by Zhong, Xiali, Yi, Xing, da Silveira E Sá, Rita de Cássia, Zhang, Yujing, Liu, Kaihua, Xiao, Fang, Zhong, Caigao

“…To investigate the toxic mechanism of hexavalent chromium Cr(VI) and search for an antidote for Cr(VI)-induced cytotoxicity, a study of mitochondrial…”
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Role of Mitochondrial Electron Transport Chain Dysfunction in Cr(VI)-Induced Cytotoxicity in L-02 Hepatocytes by Xiao, Fang, Li, Yanhong, Luo, Lei, Xie, Ying, Zeng, Ming, Wang, An, Chen, Hanchun, Zhong, Caigao

“…Background: Hexavalent chromium [Cr(VI)] and its compounds (e.g. chromates), which are extensively used in numerous industrial processes including leather…”
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Desipramine Ameliorates Cr(VI)-Induced Hepatocellular Apoptosis via the Inhibition of Ceramide Channel Formation and Mitochondrial PTP Opening by Luo, Lei, Xie, Ying, Wang, An, Liu, Xinmin, Xiao, Fang, Zhong, Xiali, Zhong, Caigao

“…Background: Hexavalent chromium (Cr(VI)) is a common environmental pollutant. Cr(VI) exposure can lead to severe damage in the liver, but the preventive…”
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Effect of Hexavalent Chromium on Electron Leakage of Respiratory Chain in Mitochondria Isolated from Rat Liver by Xie, Ying, Zhong, Caigao, Zeng, Ming, Guan, Lan, Luo, Lei

“…Background/Aims: In the present study, we explored reactive axygen species (ROS) production in mitochondria, the mechanism of hexavalent chromium (Cr(VI))…”
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Down-regulation of Polη expression leads to increased DNA damage, apoptosis and enhanced S phase arrest in L-02 cells exposed to hydroquinone by Hu, Gonghua, Huang, Haiyan, Yang, Lingqing, Zhong, Caigao, Xia, Bo, Yang, Yuan, Liu, Jianjun, Wu, Desheng, Liu, Qingchen, Zhuang, Zhixiong

“…► A stable cell with knockdown of Polη was successfully constructed. ► Polη deficiency led to a decrease in cell proliferation and an enhanced apoptosis. ►…”
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Expression of Clusterin suppresses Cr(VI)-induced premature senescence through activation of PI3K/AKT pathway by Zhang, Yujing, Zhang, Yiyuan, Xiao, Yuanyuan, Zhong, Caigao, Xiao, Fang

“…Our group found that long-term low-dose exposure to hexavalent chromium [Cr(VI)] in L-02 hepatocytes resulted in premature senescence, which accompanied by the…”
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Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes by Zhang, Yujing, Xiao, Fang, Zhong, Caigao, Zeng, Ming, Zou, Lianhong

“…Previous research has shown that cadmium (Cd), which accumulates primarily in the liver and kidneys, could cause cell cycle arrest in various cell types. In…”
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Retraction: Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes by Zhang, Yujing, Xiao, Fang, Zhong, Caigao, Zeng, Ming, Zou, Lianhong

“…Retraction of 'Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes' by Yujing Zhang et al. ,…”
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Retracted Article: Cd induces G2/M cell cycle arrest by up-regulating miR-133b via directly targeting PPP2R2D in L02 hepatocytes by Zhang, Yujing, Xiao, Fang, Zhong, Caigao, Zeng, Ming, Zou, Lianhong

“…Previous research has shown that cadmium (Cd), which accumulates primarily in the liver and kidneys, could cause cell cycle arrest in various cell types. In…”
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The role of STIM1 in the Cr(vi)-induced [Ca2+]i increase and cell injury in L-02 hepatocytes by Yi, Xing, Zhang, Yujing, Zhong, Caigao, Zhong, Xiali, Xiao, Fang

“…Hexavalent chromium [Cr( vi )] is a potent cytotoxin and carcinogen. In recent years, drinking water contamination with Cr( vi ) has become a worldwide problem…”
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In vitro cytotoxicity assessment of roundup (glyphosate) in L-02 hepatocytes by Luo, Lei, Wang, Fei, Zhang, Yiyuan, Zeng, Ming, Zhong, Caigao, Xiao, Fang

“…The goal of the present study was to elucidate the in vitro cytotoxicity of Roundup and to reveal the possible related mechanisms in L-02 hepatocytes. By…”
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Hexavalent chromium induces energy metabolism disturbance and p53-dependent cell cycle arrest via reactive oxygen species in L-02 hepatocytes by Xiao, Fang, Feng, Xiaotao, Zeng, Ming, Guan, Lan, Hu, Qingqing, Zhong, Caigao

“…Hexavalent chromium [Cr(VI)] has become a non-negligible pollutant in the world. Cr(VI) exposure leads to severe damage to the liver, but the mechanisms…”
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A Ca2+ chelator ameliorates chromium (VI)-induced hepatocyte L-02 injury via down-regulation of Voltage-Dependent Anion Channel 1 (VDAC1) expression by Yi, Xing, Xiao, Fang, Zhong, Xiali, Duan, Yujie, Liu, Kaihua, Zhong, Caigao

“…Abstract Hexavalent chromium could result in cell malfunctions. Intracellular Ca2+ ([Ca2+ ]i ) content and VDAC1 expression are both important features related…”
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Reactive Oxygen Species Play a Central Role in Hexavalent Chromium-Induced Apoptosis in Hep3B Cells without the Functional Roles of p53 and Caspase-3 by Zeng, Ming, Xiao, Fang, Zhong, Xiali, Jin, Feng, Guan, Lan, Wang, An, Liu, Xinmin, Zhong, Caigao

“…Background/Aims: Hexavalent chromium [Cr(VI)] and its compounds, which have the extensive application in diverse industries including metallurgy, textile and…”
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