Search Results - "Zhiyun Cao"
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Babao Dan induces gastric cancer cell apoptosis via regulating MAPK and NF-κB signaling pathways
Published in Journal of international medical research (01-10-2019)“…Objective The objective was to further investigate apoptosis induction by Babao Dan (BBD), which supports its anti-tumor mechanisms, using two human gastric…”
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Tumor necrosis factor-related apoptosis-inducing ligand modulates angiogenesis and apoptosis to inhibit non-small cell lung carcinoma tumor growth in mice
Published in Journal of international medical research (01-07-2019)“…Objective To investigate the anti-tumor effect and mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in non-small cell lung…”
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Bufalin Inhibits Tumorigenesis, Stemness, and Epithelial–Mesenchymal Transition in Colorectal Cancer through a C-Kit/Slug Signaling Axis
Published in International journal of molecular sciences (01-11-2022)“…Colorectal cancer (CRC) is a major source of morbidity and mortality, characterized by intratumoral heterogeneity and the presence of cancer stem cells (CSCs)…”
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Comparison of Surgical and Colonoscopy Tissue to Establish Colorectal Patient-derived Organoids
Published in Current cancer drug targets (01-01-2024)“…Patient-derived organoids (PDOs) are ex vivo models that retain the functions and characteristics of individualized source tissues, including a simulated tumor…”
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Jiedu Xiaozheng Yin Inhibits the Progression of Colitis Associated Colorectal Cancer by Stimulating Macrophage Polarization Towards an M1 Phenotype via the TLR4 Pathway
Published in Integrative cancer therapies (01-01-2024)“…To investigate the effect of Jiedu Xiaozheng Yin (JXY) on the polarization of macrophages in colitis-associated colon cancer (CAC). An orthotopic model of CAC…”
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Babao Dan inhibits the migration and invasion of gastric cancer cells by suppressing epithelial–mesenchymal transition through the TGF-β/Smad pathway
Published in Journal of international medical research (01-06-2020)“…Objective To investigate the anti-metastatic effects of Babao Dan (BBD) on gastric cancer (GC) cells (AGS and MGC80-3) and explore the underlying molecular…”
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The role of proteomics in understanding biological mechanisms of sepsis
Published in Proteomics. Clinical applications (01-02-2014)“…Sepsis is a systemic inflammatory state caused by infection. Complications of this infection with multiple organ failure lead to more lethal conditions, such…”
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Fuzheng Qingjie Granules Inhibit Growth of Hepatoma Cells via Inducing Mitochondria-Mediated Apoptosis and Enhancing Immune Function
Published in Integrative cancer therapies (01-09-2017)“…Fuzheng Qingjie (FZQJ) granules, a compound Chinese medicine, have been used as an adjuvant therapy for alimentary tract cancers. However, the underlying…”
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Babao Dan, a Traditional Chinese Medicine Formula, Arrests the G1/S Phase Transition in Gastric Cancer Cells by Activating p53 Pathway
Published in International Journal of Gerontology (01-02-2020)“…Background: Clinical studies and biological mechanism research showed that Babao Dan (BBD) exerts strong activity against many types of cancer, including…”
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Active hexose correlated compound potentiates the antitumor effects of low-dose 5-fluorouracil through modulation of immune function in hepatoma 22 tumor-bearing mice
Published in Nutrition research and practice (01-04-2015)“…BACKGROUND/OBJECTIVES: A variety of immunomodulators can improve the efficacy of low-dose chemotherapeutics. Active hexose correlated compound (AHCC), a…”
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Recent progress in the construction and application of patient-derived pancreatic cancer organoid models
Published in Zhongguo ai zheng za zhi (01-06-2024)“…Pancreatic cancer is a worldwide medical and health problem. Due to its high heterogeneity and malignant phenotype, the 5-year survival rate of pancreatic…”
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Additions to the Human Plasma Proteome via a Tandem MARS Depletion iTRAQ-Based Workflow
Published in International Journal of Proteomics (01-01-2013)“…Robust platforms for determining differentially expressed proteins in biomarker and discovery studies using human plasma are of great interest. While increased…”
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The Efficacy of Laughter Therapy on Psychological Symptoms in People With Cancer: A Systematic Review and Meta-Analysis of Randomized Controlled Studies
Published in Psycho-oncology (Chichester, England) (01-11-2024)“…Cancer patients generally have high stress levels, which often leads to depression, anxiety and other psychological problems. Laughter therapy has been used to…”
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The Role of βγ and αγ Complexes in the Assembly of Human Fibrinogen
Published in The Journal of biological chemistry (01-11-1996)“…The role of αγ and βγ dimers as intermediates in the assembly of fibrinogen was examined in cell fusion experiments using stably transfected baby hamster…”
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Jiedu Xiaozheng Yin extract targets cancer stem cells by Wnt signaling pathway in colorectal cancer
Published in Journal of ethnopharmacology (30-01-2025)“…The clinical application of the traditional Chinese medicinal formula Jiedu Xiaozheng Yin (JXY) for gastrointestinal tumors, particularly colorectal cancer…”
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Role of DCLK1 in oncogenic signaling (Review)
Published in International journal of oncology (01-11-2022)“…Doublecortin-like kinase 1 (DCLK1) has been identified as a novel biomarker of cancer stem cells among several different cancer types, including colon, breast,…”
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Tuft cells: an emerging therapeutic target for pancreatitis and pancreatic cancer?
Published in Expert opinion on therapeutic targets (01-12-2020)Get more information
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Tuft and Cancer Stem Cell Marker DCLK1: A New Target to Enhance Anti-Tumor Immunity in the Tumor Microenvironment
Published in Cancers (17-12-2020)“…Microtubule-associated doublecortin-like kinase 1 (DCLK1) is an accepted marker of tuft cells (TCs) and several kinds of cancer stem cells (CSCs), and emerging…”
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Identification of mini‐chromosome maintenance 8 as a potential prognostic marker and its effects on proliferation and apoptosis in gastric cancer
Published in Journal of cellular and molecular medicine (01-12-2020)“…Mini‐chromosome maintenance (MCM) proteins play important roles in initiating eukaryotic genome replication. The MCM family of proteins includes several…”
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Abstract LB219: DCLK1 is a novel therapeutic target for gastric and colorectal cancers as demonstrated by patient-derived organoids assays
Published in Cancer research (Chicago, Ill.) (05-04-2024)“…Abstract Gastrointestinal cancers, including gastric cancer (GC) and colorectal cancer (CRC), continue to be devastating diseases despite advances in…”
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