Search Results - "Zhirnov, Oleg P"

Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling by Zhirnov, Oleg P, Klenk, Hans-Dieter

“…PI3k-Akt and p53 pathways are known to play anti- and pro-apoptotic roles in cell death, respectively. Whether these pathways are recruited in influenza virus…”
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Cleavage of Influenza A Virus Hemagglutinin in Human Respiratory Epithelium Is Cell Associated and Sensitive to Exogenous Antiproteases by Zhirnov, Oleg P, Ikizler, Mine R, Wright, Peter F

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Avian flu: «for whom the bell tolls»? by Zhirnov, Oleg P., Lvov, Dmitry K.

“…The family Orthomyxoviridae consists of 9 genera, including Alphainfluenza virus, which contains avian influenza viruses. In two subtypes H5 and H7 besides…”
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Modern approaches to treating cancer with oncolytic viruses by Vorobjeva, Irina V., Zhirnov, Oleg P.

“…According to the World Health Organization, cancer is the second leading cause of death in the world. This serves as a powerful incentive to search for new…”
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Method for evaluating the neuraminidase activity of receptor-destroying enzyme (RDE) compounds using the influenza virus by Fedorov, Artem Yu, Zhirnov, Oleg P.

“…Introduction. The classic hemagglutination inhibition reaction (RTGA) is used to determine the level of antiviral antibodies in human and animal serum…”
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Alterations in caspase cleavage motifs of NP and M2 proteins attenuate virulence of a highly pathogenic avian influenza virus by Zhirnov, Oleg P, Klenk, Hans-Dieter

“…Abstract The NP and M2 proteins of influenza A viruses are cleaved by caspases. M2 cleavage occurs with both human and avian viruses, whereas NP cleavage is…”
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Cellular immune response in infected mice to NSP protein encoded by the negative strand NS RNA of influenza A virus by Zhirnov, Oleg P., Konakova, Tatyana E., Anhlan, Darisuren, Ludwig, Stephan, Isaeva, Elena I.

“…Influenza A virus belongs to a family of enveloped viruses with an RNA genome of negative polarity consisting of 8 RNA segments. The transcription of this RNA…”
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Aprotinin, a Protease Inhibitor, Suppresses Proteolytic Activation of Pandemic H1N1v Influenza Virus by Zhirnov, Oleg P, Matrosovich, Tatyana Y, Matrosovich, Mikhail N, Klenk, Hans-Dieter

“…Background: The recent emergence of pandemic influenza virus H1N1v stresses the need for the development of new anti-influenza drugs. Methods: Host proteases…”
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Protection against mouse and avian influenza A strains via vaccination with a combination of conserved proteins NP, M1 and NS1 by Zhirnov, Oleg P., Isaeva, Elena I., Konakova, Tatyana E., Thoidis, Galini, Piskareva, Lyudmila M., Akopova, Irina I., Kartashov, Alex, Altstein, Anatoly D., Ilyinskii, Petr O., Shneider, Alexander M.

“…Background  Experimental data accumulated over more than a decade indicate that cross‐strain protection against influenza may be achieved by immunization with…”
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The in situ Spatial Arrangement of the Influenza A Virus Matrix Protein M1 Assessed by Tritium Bombardment by Shishkov, Alexander V., Goldanskii, Vitalii I., Baratova, Ludmila A., Fedorova, Natalia V., Ksenofontov, Alexander L., Zhirnov, Oleg P., Galkin, Alexander V.

“…Intact influenza A virions were bombarded with thermally activated tritium atoms, and the intramolecular distribution of the label in the matrix protein M1 was…”
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Influenza virus pathogenicity is determined by caspase cleavage motifs located in the viral proteins by Zhirnov, Oleg P, Syrtzev, Vladimir V

“…Almost all influenza virus proteins are found to contain caspase cleavage motifs. Two caspase cleavage consensus sequences, EXD downward arrowY and D/EXXD…”
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The Unique Genome of the Virus and Alternative Strategies for its Realization by Zhirnov, O P

“…Dedicated to the 130th anniversary of Dmitry Ivanovsky's discovery of the virus kingdom as a new form of biological life. The genome of some RNA-containing…”
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Histones as a Target for Influenza Virus Matrix Protein M1 by Zhirnov, Oleg P., Klenk, Hans-Dieter

“…Matrix protein M1 purified from influenza A and B viruses has been analyzed for its ability to specifically interact with cellular proteins by immune…”
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High protection of animals lethally infected with influenza virus by aprotinin-rimantadine combination by Zhirnov, O P

“…The successful therapeutic synergism of aprotinin and rimantadine, which are known to attack different viral targets, was demonstrated in…”
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Suppression of Influenza Virus Replication in Infected Mice by Protease Inhibitors by Zhirnov, Oleg P, Ovcharenko, Alexander V, Bukrinskaya, Alice G

“…The D.I. Ivanovsky Institute of Virology, Moscow, U.S.S.R. Administration of the protease inhibitors, -aminocaproic acid or aprotinins, to mice infected with…”
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Proteolytic Activation of Influenza WSN Virus in Cultured Cells is Performed by Homologous Plasma Enzymes by Zhirnov, Oleg P, Ovcharenko, Alexander V, Bukrinskaya, Alice G

“…The D.I. Ivanovsky Institute of Virology Academy of Medical Sciences, Moscow, U.S.S.R. The effect of chick embryo allantoic fluid, porcine plasma or canine…”
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