Search Results - "Zhiqiang Han"

Immune checkpoint therapy for solid tumours: clinical dilemmas and future trends by Sun, Qian, Hong, Zhenya, Zhang, Cong, Wang, Liangliang, Han, Zhiqiang, Ma, Ding

“…Immune-checkpoint inhibitors (ICBs), in addition to targeting CTLA-4, PD-1, and PD-L1, novel targeting LAG-3 drugs have also been approved in clinical…”
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Experimental study on the heat transfer behavior and contact pressure at the casting-mold interface in squeeze casting of aluminum alloy by Wang, Feifan, Ma, Qingxian, Meng, Wen, Han, Zhiqiang

“…•Rigorous methods for obtaining casting-mold interfacial heat transfer coefficient.•Direct measurement of the casting-mold interface pressure in direct squeeze…”
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Numerical Modeling of the Macrosegregation Improvement in Continuous Casting Blooms by Using F-EMS by Li, Shaoxiang, Han, Zhiqiang, Zhang, Jiaquan

“…A three-dimensional mathematic model based on segmentation that joins the electromagnetic field, melt flow, heat transfer, solidification and solute transport…”
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The synthetic lethality of targeting cell cycle checkpoints and PARPs in cancer treatment by Li, Shuangying, Wang, Liangliang, Wang, Yuanyuan, Zhang, Changyi, Hong, Zhenya, Han, Zhiqiang

“…Continuous cell division is a hallmark of cancer, and the underlying mechanism is tumor genomics instability. Cell cycle checkpoints are critical for enabling…”
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Phylogeography study of Ammodytes personatus in Northwestern Pacific: Pleistocene isolation, temperature and current conducted secondary contact by Han, Zhiqiang, Yanagimoto, Takashi, Zhang, Yaping, Gao, Tianxiang

“…To assess the role of historical process and contemporary factors in shaping population structures in Northwestern Pacific, mitochondrial control region…”
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PNO1 inhibits autophagy-mediated ferroptosis by GSH metabolic reprogramming in hepatocellular carcinoma by Hu, Xiaomeng, He, Yuchao, Han, Zhiqiang, Liu, Wei, Liu, Dongming, Zhang, Xihao, Chen, Lu, Qi, Lisha, Chen, Liwei, Luo, Yi, Li, Qiang, Chen, Peng, Wu, Qiang, Zhu, Xiaolin, Guo, Hua

“…Effective strategies for hepatocellular carcinoma, which is the second leading cause of death worldwide, remain limited. A growing body of emerging evidence…”
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Recursion Enhanced Random Forest With an Improved Linear Model (RERF-ILM) for Heart Disease Detection on the Internet of Medical Things Platform by Guo, Chunyan, Zhang, Jiabing, Liu, Yang, Xie, Yaying, Han, Zhiqiang, Yu, Jianshe

“…Nowadays, Heart disease is one of the crucial impacts of mortality in the country. In clinical data analysis, predicting cardiovascular disease is a primary…”
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Landscape of Myeloid-derived Suppressor Cell in Tumor Immunotherapy by Hao, Zhaonian, Li, Ruyuan, Wang, Yuanyuan, Li, Shuangying, Hong, Zhenya, Han, Zhiqiang

“…Myeloid-derived suppressor cells (MDSC) are a group of immature cells that produced by emergency myelopoiesis. Emerging evidences have identified the vital…”
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How Oratosquilla oratoria compound eye response to the polarization of light: In the perspective of vision genes and related proteins by Fangrui, Lou, Jiaoli, Zhou, Schunter, Celia, Lin, Wang, Yongzheng, Tang, Zhiqiang, Han, Bin, Kang

“…The special rhabdom structure of the mid-band ommatidium in compound eye contributes to the mantis shrimp being the only animal species known to science that…”
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Macrophage, the potential key mediator in CAR-T related CRS by Hao, Zhaonian, Li, Ruyuan, Meng, Li, Han, Zhiqiang, Hong, Zhenya

“…Chimeric antigen receptor (CAR) T cell therapy is a new frontier in cancer therapy. The toxicity of cytokine release syndrome (CRS) has become one of the major…”
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Metformin combined with cisplatin reduces anticancer activity via ATM/CHK2-dependent upregulation of Rad51 pathway in ovarian cancer by Zhang, Jingjing, Zhou, Ping, Wu, Tiancheng, Zhang, Liping, Kang, Jiaqi, Liao, Jing, Jiang, Daqiong, Hu, Zheng, Han, Zhiqiang, Zhou, Bo

“…Ovarian cancer (OC) is the deadliest malignancy of the female reproductive system. The standard first-line therapy for OC involves cytoreductive surgical…”
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Full-length transcripts facilitates Portunus trituberculatus genome structure annotation by Lou, Fangrui, Han, Zhiqiang

“…Portunus trituberculatus is an ideal model for elucidating crustacean genetic networks. Here we combined single molecule real-time (SMRT) sequencing and…”
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Population genomics provides insights into the population structure and temperature-driven adaptation of Collichthys lucidus by Zhao, Linlin, Qu, Fangyuan, Song, Na, Han, Zhiqiang, Gao, Tianxiang, Zhang, Zhaohui

“…Understanding the genetic structure and local adaptive evolutionary mechanisms of marine organisms is crucial for the management of biological resources. As…”
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The “Hand as Foot” teaching method in the ultrasonographic characteristics of brachial-plexus block anesthesia by Li, Junhui, Han, Zhiqiang, Liu, Rui

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Chromosomal-scale genome assembly and annotation of the land slug (Meghimatium bilineatum) by Sun, Shaolei, Han, Xiaolu, Han, Zhiqiang, Liu, Qi

“…Meghimatium bilineatum is a notorious pest land slug used as a medicinal resource to treat ailments in China. Although this no-model species is unique in terms…”
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Calculation method of spherically expanding flame propagation radius to consider ignition electrode effects by Fan, Likang, Fu, Xin, Hu, Mingjie, Yan, Yan, Zuo, Zinong, Han, Zhiqiang, Fang, Jia, Xiao, Bang

“…Ignition electrodes have an immense impact on the accurate measurement of the flame propagation spherical radius. In this study, a flame-radius calculation…”
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Comparative transcriptome analysis of low- and high-latitude populations of Charybdis japonica under temperature stress by Sun, Shaolei, He, Zhiqi, Zhang, Feijun, Han, Zhiqiang

“…Global climate change has caused rapid temperature changes in marine environments. Understanding how marine organisms respond to temperature changes can help…”
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Genetic differentiation and genetic structure of mixed-ploidy Camellia hainanica populations by Tong, Hailang, Deng, Hongda, Han, Zhiqiang

“…, which is common in China's Hainan Province, is an important woody olive tree species. Due to many years of geographic isolation, has not received the…”
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Cervical cancer heterogeneity: a constant battle against viruses and drugs by Sun, Qian, Wang, Liangliang, Zhang, Cong, Hong, Zhenya, Han, Zhiqiang

“…Cervical cancer is the first identified human papillomavirus (HPV) associated cancer and the most promising malignancy to be eliminated. However, the…”
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Transcriptome Analysis of Marbled Rockfish Sebastiscus marmoratus under Salinity Stress by He, Zhiqi, Shou, Chenyan, Han, Zhiqiang

“…The marbled rockfish, , belongs to the euryhaline fish and is an oviparous scleractinian fish. There are few studies on the adaptation mechanism, functional…”
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