Search Results - "Zhilyaeva, T. V."
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Homocysteine in Schizophrenia: Independent Pathogenetic Factor with Prooxidant Activity or Integral Marker of Other Biochemical Disturbances?
Published in Schizophrenia Research and Treatment (2021)“…A wide range of studies have demonstrated that hyperhomocysteinemia is associated with the risk of schizophrenia, but currently available assumptions about the…”
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Pterin metabolism, inflammation and oxidative stress biochemical markers in schizophrenia: Factor analysis and assessment of clinical symptoms associations
Published in Progress in neuro-psychopharmacology & biological psychiatry (20-12-2023)“…Various aspects of folate and tetrahydrobiopterin (BH4) metabolism disturbances have been detected in patients with schizophrenia.Data were obtained that…”
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Tetrahydrobiopterin deficiency in schizophrenia: Biochemical and clinical aspects
Published in Journal of psychiatric research (01-09-2022)“…It was reported that the levels of tetrahydrobiopterin (BH4) are reduced in schizophrenia. However, mechanisms of BH4 deficiency in schizophrenia had not been…”
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Cognitive impairments in schizophrenia and their impact on oxidative stress
Published in Obozrenie psikhiatrii i medit︠s︡inskoĭ psikhologii imeni V.M. Bekhtereva (15-10-2022)“…The article is devoted to modern concepts of cognitive disorders in schizophrenia. Neurocognitive deficits can be expressed in impaired attention, auditory…”
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Association of affective disorders and MTHFR, MTR, and MTRR gene polymorphisms: preliminary results of a family study
Published in Nevrologii͡a︡, neĭropsikhiatrii͡a︡, psikhosomatika (21-10-2022)“…Genetic polymorphisms associated with impaired one-carbon metabolism (1-CM) can be a risk factor not only for somatic and neurological diseases, but also for…”
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Dysbiosis of intestinal microbiota in autism spectrum disorders: new horizons in search for pathogenetic approaches to therapy. Part 1. Features of intestinal microbiota in autism spectrum disorders
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (04-03-2021)“…The first part of the literature review on the role of intestinal microbiota dysbiosis in the pathogenesis of autism spectrum disorders (ASD) includes recent…”
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Disturbances of intestinal microbiota in autism spectrum disorders: new horizons in search for pathogenetic approaches to therapy. Рart 3. Рotential strategies of influence on gut-brain axis for correction of symptoms of autism spectrum disorders
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (01-07-2021)“…The third part of the literature review on the role of intestinal microbiota disturbances in the pathogenesis of autism spectrum disorders (ASD) is devoted to…”
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Dysbiosis of intestinal microbiota in autism spectrum disorders: new horizons in search for pathogenetic approaches to therapy. Part 2. Gut–brain axis in pathogenesis of autism spectrum disorders
Published in Žurnal mikrobiologii, ėpidemiologii i immunobiologii (01-05-2021)“…The second part of the literature review on the role of intestinal microbiota disturbances in the pathogenesis of autism spectrum disorders (ASD) is devoted to…”
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Interleukin-6 in schizophrenia is associated with negative symptoms, side effects of therapy and smoking: results of a pilot study
Published in Obozrenie psikhiatrii i medit︠s︡inskoĭ psikhologii imeni V.M. Bekhtereva (31-07-2022)“…Interleukin-6 (IL-6) is one of the most important pro-inflammatory markers with immunomodulatory activity associated with schizophrenia. The possible…”
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The interaction of folate cycle enzyme genes and the risk of extrapyramidal side effects of antipsychotics
Published in Nevrologii͡a︡, neĭropsikhiatrii͡a︡, psikhosomatika (2021)“…Personalized medicine means the selection of therapy for patients, taking into account the assessment of genetic risk factors for side effects. A number of…”
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Biochemical disturbances in schizophrenia — a «window of opportunity
Published in Obozrenie psikhiatrii i medit︠s︡inskoĭ psikhologii imeni V.M. Bekhtereva (17-12-2022)“… Introduction: Currently, there is a large amount of data that inflammatory and oxidative stress biomarkers, pterin metabolism disturbances and other…”
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Association between redox imbalance, pterin metabolism markers, and early extrapyramidal side effects of antipsychotics in schizophrenia: pilot study
Published in Nevrologii͡a︡, neĭropsikhiatrii͡a︡, psikhosomatika (17-04-2022)“…Antipsychotics (AP) administration in schizophrenia patients is associated with several side effects (SE), in particular, with extrapyramidal (EP). Data…”
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The double-blind randomized placebo-controlled trial of N-acetylcysteine use in schizophrenia: preliminary results
Published in Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2020)“…Currently, oxidative stress as part of the pathogenesis of schizophrenia attracts much attention. In this regard, it becomes relevant to assess the level of…”
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Genetic markers of One-Carbon Metabolism Disorders in Schizophrenial
Published in Obozrenie psikhiatrii i medit︠s︡inskoĭ psikhologii imeni V.M. Bekhtereva (09-12-2019)“…The paper presents the results of the literature review and the authors’ own studies of the association of several several single-nucleotide genetic…”
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The role of nutrients and probiotics in treatment of depression
Published in Bi͡u︡lletenʹ Sibirskoĭ medit͡s︡iny (04-01-2022)“…Currently, a growing amount of data is emerging on the role of various environmental factors (nutrients, gut microbiota, etc.) on formation of depression. The…”
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New approach to mental disorders systematics: starting point or point of view?
Published in Obozrenie psikhiatrii i medit︠s︡inskoĭ psikhologii imeni V.M. Bekhtereva (11-10-2020)“…The search for new approaches to the mental disordersclassification is one of the priority tasks in modern psychiatry. Current approaches evaluate mental…”
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Tetrahydrobiopterin deficiency in schizophrenia as a new target for personalized medicine
Published in Obozrenie psikhiatrii i medit︠s︡inskoĭ psikhologii imeni V.M. Bekhtereva (17-12-2020)“…Tetrahydrobiopterin (BH4) is an important cofactor, that involved in the synthesis of dopamine, norepinephrine, and serotonin, as well as affecting the…”
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Association study of methylenetetrahydrofolate reductase genetic polymorphism 677C>T with schizophrenia in hospitalized patients in population of European Russia
Published in Asian journal of psychiatry (01-02-2018)“…•Genetic polymorphism MTHFR677C>T among representatives of Russian population is a possible risk factor for schizophrenia.•This genetic factor associated with…”
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Single nucleotide polymorphism MTHFR677C>T and the severity of metabolic side effects of antipsychotics in patients with schizophrenia: the results of a pilot study
Published in Obozrenie psikhiatrii i medit︠s︡inskoĭ psikhologii imeni V.M. Bekhtereva (02-11-2018)“…To predict the development of side effects and personalized selection of drug therapy, it seems relevant to study the association of individual genetic risk…”
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Psychopathological characteristics and social functioning of the schizophrenic patients with the T allele of the MTHFR677C>T polymorphism
Published in Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova (2016)“…To compare the severity of psychopathological symptoms and characteristics of personal and social functioning in patients with schizophrenia, carriers of…”
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